Genetic Counseling (GC)

遗传咨询（GC）

• 批准号: 9689959
• 负责人: Wendy K Kohlmann
• 金额: $ 1.78万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9689959
• 关键词: Abbreviations; Address; Advanced Malignant Neoplasm; Advisory Committees; Amendment; BRCA1 gene; BRCA2 gene; Back; Basic Science; Behavioral Research; Behavioral trial; Budgets; CDKN2A gene; Cancer Center; Cancer Center Support Grant; Clinical; Clinical Research; Clinical Trials; Communication; Community Health Education; Community Healthcare; Complex; Consultations; Counseling; Data; Distant; Early Diagnosis; Education; Environment; Ethical Issues; Ethics; Faculty; Family; Funding; Genes; Genetic; Genetic Counseling; Genetic Research; Genetic Services; Genetic screening method; Genetic study; Goals; Health Personnel; Hereditary Malignant Neoplasm; Individual; Inheritance Patterns; Inherited; Institutes; Intervention; Investigation; Knowledge; Laboratories; Lead; Legal; Location; Malignant Neoplasms; Medical Genetics; Medical Records; Methodology; Mission; Modeling; Morbidity - disease rate; Outcome; Participant; Patient Education; Patient Recruitments; Patients; Peer Review; Penetrance; Persons; Play; Population Database; Population Research; Predisposition; Professional Education; Professional counselor; Protocols documentation; Provider; Psychosocial Influences; Publications; Recording of previous events; Research; Research Design; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Resources; Risk; Risk Assessment; Role; Sampling; Services; Supervision; Surveys; Syndrome; Training Programs; Translating; Universities; Utah; Work; acronyms; behavioral outcome; behavioral study; cancer genetics; cancer prevention; cancer risk; cancer type; clinical care; clinical practice; cohort; cost; design; ethical legal social implication; experience; flexibility; gene discovery; genetic counselor; implementation research; improved; lectures; member; mortality; neoplasm resource; outreach; personalized cancer therapy; psychosocial; recruit; research study; satisfaction; success; symposium; translational research program

GENETIC COUNSELING SHARED RESOURCE ABSTRACT The Genetic Counseling (GC) Shared Resource provides cutting-edge genetic services and expertise at an affordable cost to University of Utah (U of U) investigators conducting research related to the inherited basis of cancer. The GC Shared Resource has provided clinical genetics services and supported genetic research at Huntsman Cancer Institute (HCI) since 2003. It was first competed for CCSG support in 2009. Wendy Kohlmann, MS, CGC, a senior genetic counselor, has managed the core since 2006; she oversees a team that includes four additional board-certified genetic counselors and support staff. To achieve its goal of advancing cancer genetics research, the GC Shared Resource provides services including: identifying and recruiting appropriate participants and controls for genetic studies, aiding in study design, addressing ethical and psychosocial issues associated with genetic research, collecting and interpreting family histories, stratifying risk, developing and implementing tailored genetic counseling interventions, and interpreting data. The GC team works individually with investigators to inform them about the services, expertise, infrastructure, data, and biospecimens available through the GC Shared Resource for genetic research and to determine the feasibility and appropriate design of potential studies. The Resource supports funded research through the course of the project, from study design to publication stages. Individuals and families with hereditary cancer susceptibilities are rare, and identifying and recruiting participants for genetic research has the potential to be cost prohibitive. The GC Shared Resource adds important value to the Cancer Center by identifying and maintaining cohorts of individuals and families with various cancer risk profiles so samples and data are readily available for investigators. The GC Shared Resource has also expanded research opportunities by providing infrastructure to return genetic findings back to participants. The GC Shared Resource contributes to a robust translational research program in which genetic discoveries lead to subsequent behavioral and clinical studies, thereby contributing to cancer genetic research at the U of U, as well as cancer prevention and personalized cancer treatment at HCI. The GC Shared Resource is a Cancer Center-managed facility with supervision from HCI Directors and a Faculty Advisory Committee. Surveys are used to assess user satisfaction. The Resource is located in HCI and is thus easily accessible to all Cancer Center members and other campus users. In 2013, use of the Resource by Cancer Center members with peer-reviewed funding exceeded 80%, while the CCSG budget request is only 6% ($37,894) of the total proposed budget.

遗传咨询共享资源 抽象的 遗传咨询 (GC) 共享资源提供尖端的遗传服务和专业知识 犹他大学 (U of U) 研究人员进行遗传基础相关研究的费用可承受 癌症。 GC 共享资源提供了临床遗传学服务并支持遗传研究 亨斯迈癌症研究所 (HCI) 自 2003 年成立。它于 2009 年首次竞争 CCSG 支持。 Wendy Kohlmann，MS，CGC，高级遗传咨询师，自 2006 年以来一直管理核心；她管理着一个团队 包括另外四名经董事会认证的遗传咨询师和支持人员。 为了实现推进癌症遗传学研究的目标，GC 共享资源提供服务 包括：确定和招募适当的参与者和基因研究的控制，协助研究 设计、解决与基因研究相关的伦理和社会心理问题、收集和 解读家族史、分层风险、制定和实施量身定制的遗传咨询 干预和解释数据。 GC 团队与调查人员单独合作，告知他们有关 通过 GC 共享资源可获取服务、专业知识、基础设施、数据和生物样本 遗传研究并确定潜在研究的可行性和适当的设计。资源 在项目的整个过程中（从研究设计到出版阶段）支持受资助的研究。 具有遗传性癌症易感性的个人和家庭很少见，识别和招募 基因研究的参与者可能成本过高。 GC 共享资源添加 通过识别和维护患有癌症的个人和家庭群体，对癌症中心具有重要价值 各种癌症风险概况，因此研究人员可以轻松获得样本和数据。 GC 共享 Resource 还通过提供基础设施来返回遗传发现，从而扩大了研究机会 给参与者。 GC 共享资源有助于强大的转化研究计划，其中 遗传发现导致随后的行为和临床研究，从而有助于癌症遗传 犹他大学的研究，以及 HCI 的癌症预防和个性化癌症治疗。 GC 共享资源是一个由癌症中心管理的设施，由 HCI 董事和 教师顾问委员会。调查用于评估用户满意度。该资源位于 HCI 因此，所有癌症中心成员和其他校园用户都可以轻松访问。 2013 年，使用 癌症中心成员提供的同行评审资金超过 80%，而 CCSG 预算 请求仅占拟议预算总额的 6%（37,894 美元）。