Genetic Counseling (GC)

遗传咨询（GC）

• 批准号: 10611311
• 负责人: Wendy K Kohlmann
• 金额: $ 14.37万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-09 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10611311
• 关键词: Address; Adherence; Applications Grants; Area; Basic Science; Behavioral Research; Cancer Biology; Cancer Center; Cancer Center Support Grant; Catchment Area; Chemoprevention; Clinic; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Collection; Communication; Consultations; Data; Effectiveness; Electronic Health Record; Ensure; Ethics; Familial Adenomatous Polyposis Syndrome; Funding; Genes; Genetic; Genetic Anticipation; Genetic Counseling; Genetic Research; Genetic Services; Goals; Grant; Guidelines; Hereditary Malignant Neoplasm; Hereditary Neoplastic Syndromes; Image; Individual; Inherited; Intervention; Malignant Neoplasms; Medical Genetics; Methods; Mission; National Cancer Institute; Oncology; Outcome; Participant; Patient-Focused Outcomes; Patients; Peer Review; Population; Population Policies; Principal Investigator; Program Research Project Grants; Protocols documentation; Publications; Qualifying; Recording of previous events; Research; Research Design; Research Institute; Research Personnel; Resource Sharing; Resources; Risk; Risk Management; Rural Population; Sampling; Science; Scientific Advances and Accomplishments; Services; Syndrome; Translating; Translations; Utah; Work; anticancer research; cancer care; cancer genetics; cancer predisposition; cancer risk; clinical care; clinical implementation; clinical phenotype; clinically significant; cohort; design; ethical, legal, and social implication; gene discovery; genetic analysis; genetic counselor; genetic information; genetic testing; innovation; member; novel; novel strategies; primary care patient; programs; recruit; screening; tool; translational genetics

GENETIC COUNSELING SHARED RESOURCE ABSTRACT The Genetic Counseling Shared Resource (GC) facilitates basic science, clinical, and behavioral research necessary to translate genetic discoveries into clinical care. GC has provided clinical genetics services and supported genetic research at Huntsman Cancer Institute (HCI) since 2003 (supported by the Cancer Center Support Grant since 2009) and has been directed by Wendy Kohlmann, MS, CGC, since 2006. GC is quintessential to HCI’s mission and builds on HCI’s long history of gene discovery by leading practice-changing research endeavors to determine the clinical utility of genetic testing, optimal methods for risk communication and delivery of genetic counseling, and strategies to manage risk conveyed by inherited cancer predispositions. GC is integral to a major goal of the Cancer Center, bringing scientific discoveries to the clinic and into applications for the population. GC provides several key services necessary for translational genetic research, including identifying cohorts of patients for gene research or studies of syndromes; helping investigators design studies to optimally incorporate genetic information and to anticipate and address ethical, legal, and social issues related to genetic analysis; providing genetic counseling interventions; and collecting clinical phenotypes and longitudinal outcomes data. The aims of GC are 1) to provide cancer genetics expertise, genetic counseling services, and interventions, and 2) to support the scientific research objectives of the Cancer Center, especially in the context of translation of genetics to the clinic and population. Access to research genetic counseling services has allowed Cancer Center members to study novel approaches for providing genetic information and to include participants across our catchment area, the State of Utah. GC adds value to the Cancer Center by ensuring genetics expertise is available to all Cancer Center members and clinical investigators. The broad impact of GC across HCI is indicated by its contribution to 61 publications since 2014. Cancer Center members with peer-reviewed funding comprise 53% of the users, and 100% of GC’s work is cancer-related. HCI’s establishment of a top-quality, research-oriented Genetic Counseling Shared Resource is highly innovative and unique among National Cancer Institute cancer centers. The Director and staff of the Shared Resource participate in national committees, and they extend the impact of HCI research by incorporating findings into guidelines for genetic testing and management of hereditary cancer. GC allows HCI to excel in all areas of hereditary cancer research and to be a leader in genetic discoveries and translation of findings into clinical implementation and population policy.

遗传咨询共享资源 摘要 遗传咨询共享资源(GC)促进基础科学、临床和行为研究 将基因发现转化为临床护理所必需的。GC提供临床遗传学服务和 自2003年起支持亨斯迈癌症研究所(HCI)的基因研究(由癌症中心提供支持 支持赠款)，自2006年以来一直由CGC硕士温迪·科尔曼指导。GC是 HCI使命的精髓，并通过领先的实践变革建立在HCI悠久的基因发现历史基础上 研究致力于确定基因检测的临床效用，即风险沟通的最佳方法 和提供遗传咨询，以及管理遗传性癌症风险的策略 先天倾向。GC是癌症中心的一个主要目标，为临床带来科学发现 并转化为面向大众的应用程序。GC提供翻译基因所需的几项关键服务 研究，包括确定用于基因研究或症状研究的患者队列；帮助 研究人员设计研究，以最佳方式整合遗传信息，并预测和解决伦理问题， 与基因分析有关的法律和社会问题；提供遗传咨询干预；收集 临床表型和纵向结果数据。GC的目标是：1)提供癌症遗传学 专业知识、遗传咨询服务和干预，以及2)支持科学研究目标 癌症中心，特别是在将遗传学转化为临床和人口的背景下。 获得研究遗传咨询服务使癌症中心的成员能够学习新的 提供遗传信息并将参与者包括在我们的集水区、州 犹他州。GC通过确保所有癌症中心都可以获得遗传学专业知识来增加癌症中心的价值 成员和临床研究人员。GC对整个人机界面的广泛影响体现在它对61 自2014年以来的出版物。拥有同行评审资金的癌症中心成员占用户的53%，以及 GC的工作100%都与癌症有关。 HCI建立高质量、研究型遗传咨询共享资源 在国家癌症研究所癌症中心中具有创新性和独特性。共享的董事和工作人员 资源参与国家委员会，他们通过将 遗传性癌症基因检测和治疗指南的研究结果。GC使HCI在所有方面都出类拔萃 在遗传性癌症研究领域，并在基因发现和将发现转化为 临床实施和人口政策。