Testing the effect of anti-tobacco message framing on polytobacco use in lesbian, gay, bisexual, and transgender young adults

项目摘要 多种烟草使用，定义为同时使用一种以上烟草产品，包括电子尼古丁 在女同性恋、男同性恋、双性恋和跨性别者（LGBT）的年轻成年人（YA）中，艾滋病传播系统（ENDS）的感染率正在上升。 22-40%的LGBT YA（与非LGBT YA的12-21%相比）报告过去30天使用多烟草， 不太可能认为烟草使用是有害的。低风险观念可能会加强烟草使用， 存在的差距。食品和药物管理局（FDA）烟草制品中心（CTP）被授权 教育公众了解烟草产品的风险，但没有证据说明如何有效地制定反烟草产品的框架。 多烟草风险沟通。建议的培训目标是让申请人发展先进的 健康传播科学技能;生物行为方法，包括心理生理测量; 和随机对照试验。这些技能将用于确定聚烟草的有效传播 使用风险的风险LGBT雅.该提案直接支持FDA教育公众的任务， 解决通信的研究优先领域。虽然研究表明， 虽然宣传可以成功地提高公众对烟草使用风险的认识，但宣传也有局限性， 现有的文献，如下：（1）虽然有效的风险沟通策略是行之有效的， 知道如何框定行为选择（例如，完全戒烟与转换为ENDS），以增加 复合烟草使用者的烟草风险认知和戒烟意向。(2)反烟草运动经常利用 文化定位，这是一项得到广泛支持但成本高昂的宣传战略，目的是增加高危人群 订婚没有研究通过实验测试LGBT文化目标与非文化目标的有效性。 有针对性的反烟草信息。(3)移动的多媒体信息已被用于传播吸烟 停止通信，并可能是可行的分发反多烟草信息，以LGBT雅，但这 尚未被调查。通过形成性和总结性评估，申请人将通过以下方式解决这些差距： 三个具体目标：（1）确定绝对和相对风险的反多烟草信息， 向YA传达多种烟草的风险;（2）确定文化目标对LGBT YA多种烟草的影响 使用者对反多种烟草信息的关注程度和感知效果;（3b）评估 通过短信向LGBT青年发送在目标1和2中制定的反多烟草彩信;以及（3b）估计 随着时间的推移，接触反多种烟草信息对风险认知和烟草使用的影响大小。这些 旨在支持国家癌症研究所（NCI）的烟草控制研究优先事项，以减少烟草差异 通过确定有效的反烟草信息框架和文化目标来增加多种烟草的风险 减少烟草使用的风险人群，LGBT YA。调查结果将提供公共卫生 官员，NCI和FDA CTP关于可能被利用的消息和数字媒体的关键信息 国家卫生通讯，以减少高危人群中的混合烟草使用。

PROJECT SUMMARY Polytobacco use, defined as concurrent use of more than one tobacco product including electronic nicotine delivery systems (ENDS), is rising and high in lesbian, gay, bisexual, and transgender (LGBT) young adults (YA). Between 22-40% of LGBT YA (vs 12-21% of non-LGBT YA) report past 30-day polytobacco use, and LGBT YA are less likely to perceive tobacco use as harmful. Low risk perceptions may reinforce tobacco use and widen existing disparities. The Food and Drug Administration (FDA) Center for Tobacco Products (CTP) is mandated educate the public about tobacco product risks, yet no evidence describes how to effectively frame anti- polytobacco risk communications. The proposed training objectives are for the applicant to develop advanced skills in health communication science; bio-behavioral methods, including psychophysiological measurement; and randomized controlled trials. These skills will be used to determine effective communication of polytobacco use risks to at-risk LGBT YA. This proposal directly supports the FDA’s mandate to educate the public by addressing the research priority area of Communications. While studies indicate that antitobacco communications can successfully increase public knowledge about tobacco use risks, there are limitations to the extant literature, as follows: (1) While strategies for effective risk communication are well-established, less is known about how to frame behavioral choices (e.g., total tobacco cessation vs switching to ENDS) to increase tobacco risk perceptions and intentions to quit in polytobacco users. (2) Antitobacco campaigns often leverage cultural targeting, a broadly supported but costly communications strategy, to increase at-risk population engagement. No studies have experimentally tested the effectiveness of LGBT culturally targeted vs non- targeted anti-tobacco messages. (3) Mobile multimedia messaging has been used to disseminate smoking cessation communications and may be feasible for distributing anti-polytobacco messages to LGBT YA, but this has not been investigated. Using formative and summative evaluation, the applicant will address these gaps with three Specific Aims: (1) Identify absolute and relative risk anti-polytobacco messages that effectively communicate polytobacco risks to YA; (2) Determine the effects of cultural targeting on LGBT YA polytobacco users’ attention to anti-polytobacco messages and perceived effectiveness; (3b) Assess the feasibility of delivering MMS anti-polytobacco messages developed in Aims 1 and 2 to LGBT YA via texting; and (3b) Estimate effect sizes of exposure to anti-polytobacco messages on risk perceptions and tobacco use over time. These aims support the National Cancer Institute’s (NCI) tobacco control research priority to reduce tobacco disparities by determining effective antitobacco message framing and cultural targeting to increase polytobacco risk perceptions and reduce tobacco use in an at-risk population, LGBT YA. Findings will provide public health officials, NCI, and the FDA CTP critical information about messages and digital media that may be leveraged in national health communications to reduce poly-tobacco use in at-risk populations.