Testing the effect of anti-tobacco message framing on polytobacco use in lesbian, gay, bisexual, and transgender young adults

项目总结 多种烟草使用，定义为同时使用一种以上烟草产品，包括电子尼古丁 在女同性恋者、男同性恋者、双性恋者和变性人(LGBT)年轻人(YA)中，分娩系统(END)的比例正在上升和上升。 22%-40%的LGBT YA(非LGBT YA的12%-21%)报告过去30天使用多种烟草，LGBT YA 不太可能认为吸烟有害。低风险认知可能会加强烟草使用并扩大范围 存在的差距。食品和药物管理局(FDA)烟草产品中心(CTP)被授权 教育公众烟草产品风险，但没有证据说明如何有效地制定反烟草产品 多种烟草风险沟通。建议的培训目标是为申请者开发高级 健康传播学技能；生物行为方法，包括心理生理测量； 和随机对照试验。这些技能将被用来确定多种烟草的有效沟通 利用风险来应对LGBT YA的风险。这项提案直接支持FDA通过以下方式教育公众的任务 处理通信的研究优先领域。虽然研究表明，抗烟剂 传播可以成功地增加公众对烟草使用风险的了解，但 现有文献如下：(1)虽然有效风险沟通的战略已经确立，但较少 了解如何框定行为选择(例如，完全戒烟与转向戒烟)以增加 多种烟草使用者的烟草风险认知和戒烟意向。(2)反烟草运动经常利用 文化定位，一种得到广泛支持但代价高昂的传播战略，以增加高危人群 订婚。还没有研究通过实验测试LGBT在文化上与非LGBT之间的有效性 有针对性的反烟草信息。(3)使用移动多媒体消息来传播吸烟 戒烟交流，并可能适用于向LGBT YA分发反多种烟草的信息，但这 还没有被调查。使用形成性和终结性评估，申请人将通过以下方式解决这些差距 三个具体目标：(1)确定绝对风险和相对风险有效的反多种烟草宣传 将多种烟草的风险传达给YA；(2)确定文化目标对LGBT YA多种烟草的影响 用户对反多种烟草信息的关注和感知的有效性；(3b)评估 通过短信向LGBT YA发送AIMS 1和AIMS 2中开发的反烟草彩信；以及(3b)估计 长期接触反多种烟草信息对风险认知和烟草使用的影响程度。这些 旨在支持国家癌症研究所(NCI)的烟草控制研究重点，以减少烟草差异 通过确定有效的反烟草信息框架和文化目标来增加多种烟草的风险 在高危人群LGBT YA中感知和减少烟草使用。这些发现将为公众健康提供 官员、NCI和FDA CTP有关可能被利用的消息和数字媒体的关键信息 国家卫生宣传，以减少高危人群中使用多种烟草。

PROJECT SUMMARY Polytobacco use, defined as concurrent use of more than one tobacco product including electronic nicotine delivery systems (ENDS), is rising and high in lesbian, gay, bisexual, and transgender (LGBT) young adults (YA). Between 22-40% of LGBT YA (vs 12-21% of non-LGBT YA) report past 30-day polytobacco use, and LGBT YA are less likely to perceive tobacco use as harmful. Low risk perceptions may reinforce tobacco use and widen existing disparities. The Food and Drug Administration (FDA) Center for Tobacco Products (CTP) is mandated educate the public about tobacco product risks, yet no evidence describes how to effectively frame anti- polytobacco risk communications. The proposed training objectives are for the applicant to develop advanced skills in health communication science; bio-behavioral methods, including psychophysiological measurement; and randomized controlled trials. These skills will be used to determine effective communication of polytobacco use risks to at-risk LGBT YA. This proposal directly supports the FDA’s mandate to educate the public by addressing the research priority area of Communications. While studies indicate that antitobacco communications can successfully increase public knowledge about tobacco use risks, there are limitations to the extant literature, as follows: (1) While strategies for effective risk communication are well-established, less is known about how to frame behavioral choices (e.g., total tobacco cessation vs switching to ENDS) to increase tobacco risk perceptions and intentions to quit in polytobacco users. (2) Antitobacco campaigns often leverage cultural targeting, a broadly supported but costly communications strategy, to increase at-risk population engagement. No studies have experimentally tested the effectiveness of LGBT culturally targeted vs non- targeted anti-tobacco messages. (3) Mobile multimedia messaging has been used to disseminate smoking cessation communications and may be feasible for distributing anti-polytobacco messages to LGBT YA, but this has not been investigated. Using formative and summative evaluation, the applicant will address these gaps with three Specific Aims: (1) Identify absolute and relative risk anti-polytobacco messages that effectively communicate polytobacco risks to YA; (2) Determine the effects of cultural targeting on LGBT YA polytobacco users’ attention to anti-polytobacco messages and perceived effectiveness; (3b) Assess the feasibility of delivering MMS anti-polytobacco messages developed in Aims 1 and 2 to LGBT YA via texting; and (3b) Estimate effect sizes of exposure to anti-polytobacco messages on risk perceptions and tobacco use over time. These aims support the National Cancer Institute’s (NCI) tobacco control research priority to reduce tobacco disparities by determining effective antitobacco message framing and cultural targeting to increase polytobacco risk perceptions and reduce tobacco use in an at-risk population, LGBT YA. Findings will provide public health officials, NCI, and the FDA CTP critical information about messages and digital media that may be leveraged in national health communications to reduce poly-tobacco use in at-risk populations.