COBRE Phase 2: Center for Neuroplasticity at the University of Puerto Rico

波多黎各大学(UPR)医学校园提议维持和 扩大其科布雷神经可塑性中心。中心运营的第二阶段将 显著加强机构的研究基础设施，并将影响生物医学 在全岛进行调查。科布雷神经可塑性中心的具体目标 在波多黎各大学有：1)促进初级调查人员的发展 有竞争力的研究人员从事具有直接生物医学意义的项目。我们的第一阶段 强化辅导计划将进一步加强，目标是继续 发展具有竞争力的研究文化；2)维护和加强神经成像和 根据科布雷第一阶段建立的电生理设施(NIFF)这一多站点核心设施 为研究社区提供最先进的仪器、培训和专业知识 波多黎各。Nef以分子科学研究中心(MSRC)为中心 重大的普遍定期审议基础设施投资，从战略上定位，以加强协作 各主要普遍定期审议校区之间的合作。MSRC还为许多机构提供服务 与卓越生物医学研究创意网络(INBRE)合作；3) 支持方案活动(Cobre研讨会系列，波多黎各年度神经科学 会议、科布雷研讨会、研讨会)，在 基础研究水平。预计这些活动将大大加强整个 生物医学研究基础设施，并将鼓励合作研究，导致 翻译研究项目。拟议的科布雷第二阶段倡议的主要优势 包括：1)项目总监，既是一名有成就的研究员，又是一名具有广泛经验的研究员 NIH内的资金和咨询活动，以及一位经验丰富的管理人员，有 成功启动研究和培训计划；2)经验丰富且有效 行政核心；3)一支年轻、有进取心、对早期职业生涯高度投入的团队 科学家；4)部署新的MSRC作为集成和协作的集中枢纽 研究；5)普遍定期审议行政当局充分承诺确保实现下列目标 这个项目。波多黎各大学的科布雷神经可塑性中心正在定义 在普遍定期审议系统内进行基础研究和翻译研究的途径和基准。它的 第二阶段将确保计划的持续增长和发展，以推动 波多黎各未来几十年具有竞争力的生物医学研究的轨迹。

The University of Puerto Rico (UPR) Medical Sciences Campus proposes to sustain and expand its COBRE Center for Neuroplasticity. The second phase of Center operation will significantly strengthen the research infrastructure of the institution and will impact biomedical investigation throughout the island. The specific aims of the COBRE Center for Neuroplasticity at the University of Puerto Rico are: 1) Foster development of junior investigators into competitive researchers working on projects with direct biomedical significance. Our Phase I intensive mentoring program will be further strengthened with the goal of continued development of a competitive research culture; 2) Maintain and augment the NeuroImaging and Electrophysiology Facility (NIEF) established under COBRE Phase I. This multi-site core facility provides state-of-the-art instrumentation, training, and expertise to the research community of Puerto Rico. The NIEF is centered at the Molecular Sciences Research Center (MSRC) a major UPR infrastructure investment that is strategically positioned to enhance collaborative efforts between the major UPR campuses. The MSRC also serves numerous institutions associated with partnering IDeA Networks of Biomedical Research Excellence (INBRE); 3) Support programmatic activities (COBRE Seminar Series, Annual Puerto Rico Neuroscience Conference, COBRE Symposia, Workshops) that increase interdisciplinary collaborations at the basic research level. It is anticipated that these activities will significantly strengthen the entire biomedical research infrastructure and will stimulate collaborative investigation leading to translational research projects. The major strengths of this proposed COBRE Phase II initiative include: 1) the Program Director, who is both an accomplished researcher with extensive funding and advisory activities within the NIH and an experienced administrator with a history of successful initiation of research and training programs; 2) an experienced and effective Administrative Core; 3) a team of young, aggressive and highly committed early career scientists; 4) deployment of the new MSRC as a centralized hub for integrated and collaborative research; 5) the full commitment of the UPR Administration toward assuring the stated goals of the project. The COBRE Center for Neuroplasticity at the University of Puerto Rico is defining pathways and benchmarks for basic and translational research across the UPR system. Its second phase will ensure the sustained growth and evolution of a program that will advance the trajectory of competitive biomedical research in Puerto Rico over the next decades.