UPR Center for Incubator and Technology Transfer (UPRCITT)

UPR 孵化器和技术转让中心 (UPRCITT)

• 批准号: 10793133
• 负责人: JOSE Antonio LASALDE-DOMINICCI
• 金额: $ 789.8万
• 依托单位: UNIVERSITY OF PUERTO RICO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10793133
• 关键词: Area; Basic Science; Biosensor; Biotechnology; Businesses; Cellular biology; Chemistry; Clinical; Collaborations; Core Facility; Cyclic GMP; Development; Discipline; Economic Development; Economics; Ecosystem; Entrepreneurship; Floor; Fostering; Funding; Future; Goals; Growth; HIV vaccine; Heart; Incubated; Incubators; Industry; Interdisciplinary Study; Island; Laboratories; Licensing; Molecular; Nanotechnology; National Institute of Neurological Disorders and Stroke; Natural Products; Occupations; Pharmacologic Substance; Postdoctoral Fellow; Puerto Rico; Research; Research Personnel; Science; Scientist; Services; Teacher Professional Development; Technology; Technology Transfer; Time; Training; Underrepresented Students; United States National Institutes of Health; Universities; Work; Workforce Development; animal facility; commercialization; flexibility; graduate student; innovation; instrumentation; laboratory facility; manufacture; prophylactic; research facility; structural biology; undergraduate student; vaccine development

UPR Center for Incubator and Technology Transfer (UPRCITT) We propose establishing the UPR Center for Incubator and Technology Transfer (UPRCITT) at the University of Puerto Rico (UPR) for entrepreneurial collaborative scientific research across multiple disciplines. In our endeavors for the UPRCITT, we will fit out an entire floor (20,000 ft2) in our eight-story UPR Molecular Sciences Research Center (MSRC), in the heart of San Juan, Puerto Rico (PR). With the establishment of the MSRC, the UPR has sought to foster an innovative and technologically driven economy that will generate businesses and jobs in PR (manufacturing or otherwise). Situating the UPRCITT in the MSRC would go a long way toward making this a reality. The UPRCITT floor would provide future collaborators with access to many of the Island’s best scientists, as well as much of the most sophisticated instrumentation available; and our GLP-compliant animal facilities. Furthermore, scientists accepted into the incubator space will have the opportunity of interacting within multidisciplinary research groups currently conducting research in nanotechnology, chemistry, biosensors, vaccine development, cell biology, natural products, structural biology, and other areas. The MSRC's ongoing efforts will provide leverage to the UPRCITT in attracting new researchers, small businesses, and Biotech and Pharmaceutical collaborators. An example of this being the creation of the Clinical Bioreagent Center (CBC), an NIH-NINDS-funded collaboration between UPR and local Biotech companies in PR for the development of a prophylactic HIV vaccine, and other new start-ups. The UPRCITT floor will include GLP/cGMP research facilities as well as flexible laboratory spaces for transitioning basic research concepts into pilot commercial projects. These projects could flourish for a time within the MSRC while de-risking the technology. The main goals of the UPRCITT are: (1) to enhance PR’s economic development by founding an innovation ecosystem that will stimulate the creation and incubation of start-up companies by providing cGMP state-of-the-art laboratories and CORE facilities, (2) to promote collaborations among Biotech and Pharmaceutical companies and UPR researchers, and (3) to provide workforce development by training for faculty, underrepresented undergraduate/graduate students and postdoctoral fellows to work in teams in an innovation ecosystem which will promote the culture of entrepreneurship in PR. The UPRCITT will promote PR's economic development in three ways: (1) Research conducted in these facilities will be critical to PR's economic development, in terms of both job creation on the island and spinoff projects that could be licensed and commercialized nationally. (2) The cGMP facilities will be used to form strategic alliances with industry, provide services to industry, and assist in capitalizing on new discoveries both within and outside of PR. (3) The facility will serve as an entrepreneurship and innovation training facility for underrepresented students aspiring to join the US scientific workforce. This application represents an unprecedented transformation in the UPR's research enterprise that will propel scientific discoveries into commercialization and economic growth.

孵化器和技术转让中心(UPRCITT) 我们建议在以下地点建立普遍定期审议孵化器和技术转让中心(UPRCITT) 波多黎各大学(UPR)跨多个领域的创业型协作科学研究 纪律。在我们为UPRCITT所做的努力中，我们将在我们的八层楼中布置一整层楼(20,000平方英尺) UPR分子科学研究中心(MSRC)，位于波多黎各圣胡安(PR)的中心。与 自MSRC成立以来，普遍定期审议一直致力于促进创新和科技驱动的经济 这将在公关(制造业或其他领域)创造业务和就业机会。将UPRCITT设在 MSRC将在实现这一目标方面大有作为。UPRCITT下层将提供未来 与岛上许多最好的科学家以及许多最复杂的科学家接触的合作者 提供仪器；以及我们符合GLP标准的动物设施。此外，科学家们接受了 孵化器空间目前将有机会在多学科研究小组内互动 从事纳米技术、化学、生物传感器、疫苗开发、细胞生物学、天然 产品、结构生物学等领域。MSRC正在进行的努力将为 UPRCITT在吸引新的研究人员、小企业以及生物技术和制药合作者方面发挥了重要作用。一个 这方面的例子是临床生物反应剂中心(CBC)的创建，该中心是由NIH-NINDS资助的 UPR与当地生物技术公司在PR方面的合作，以开发预防性艾滋病毒 疫苗和其他新的初创企业。UPRCITT楼层将包括GLP/cGMP研究设施以及 灵活的实验室空间，用于将基本研究概念转化为试点商业项目。这些 项目可能会在MSRC内蓬勃发展一段时间，同时降低技术风险。会议的主要目标是 UPRCITT是：(1)通过建立创新生态系统促进公关经济发展 通过提供cGMP最先进的实验室和 核心设施，(2)促进生物技术和制药公司与普遍定期审议之间的合作 研究人员，以及(3)通过培训任职人数不足的教师来提供劳动力发展 本科生/研究生和博士后研究员在创新生态系统中团队合作 将在公关中推广创业文化。UPRCITT将在#年促进PR的经济发展 三种方式：(1)在这些设施中进行的研究将在以下方面对公关的经济发展至关重要 在岛上创造就业机会，以及可以在全国范围内获得许可和商业化的衍生项目。 (2)cGMP设施将用于与行业建立战略联盟，为行业提供服务，以及 协助利用公关内外的新发现。(3)该设施将作为 为有志加入美国的代表不足的学生提供创业和创新培训设施 科学工作者。这一应用代表了普遍定期审议研究中前所未有的转变 将推动科学发现商业化和经济增长的企业。