Clinical Research Design, Epidemiology, and Biostatistics Core

临床研究设计、流行病学和生物统计学核心

• 批准号: 10213753
• 负责人: THOMAS C HULSEY
• 金额: $ 29.35万
• 依托单位: WEST VIRGINIA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10213753
• 关键词: Address; Area; Biometry; Biostatistics Core; Cardiovascular Diseases; Chronic lung disease; Clinic; Clinical; Clinical Research; Clinical Sciences; Communities; Computerized Medical Record; Consult; Consultations; Data; Data Analyses; Data Linkages; Degree program; Development; Educational workshop; Electronic Mail; Epidemic; Epidemiologic Research Design; Epidemiologist; Epidemiology; Faculty; Funding; Goals; Health; Health Priorities; Hepatitis C; Institutes; Institution; Instruction; Light; Malignant Neoplasms; Medical center; Meta-Analysis; Methods; Modality; Osteopathic Medicine; Outcome Study; Participant; Persons; Population; Population Study; Research; Research Design; Research Infrastructure; Research Personnel; Schools; Science; Scientist; Seasons; Services; Statistical Methods; Telephone; Training and Education; Translational Research; United States; Universities; Walking; West Virginia; addiction; analytical method; base; certificate program; data repository; design; epidemiology study; experience; improved; knowledge base; nervous system disorder; novel; outreach; population health; predictive modeling; response; skills; sound; statistics; tool

The overall purpose of the Clinical Research Design, Epidemiology and Biostatistics (CRDEB) Core of the West Virginia Clinical and Translational Science Institute (WVCTSI) is to provide investigators throughout West Virginia (WV) with a centrally coordinated means of analytics support. This expertise will be delivered from a group of scientists that collectively bring a comprehensive set of skills ranging from general to highly specialized expertise in biostatistics and epidemiology. The goal is to enable investigators to rigorously address WVCTSI priority health areas that include: addiction & emerging epidemics (e.g., hepatitis C), cancer, cardiovascular disease, and chronic lung disease. We propose the following three specific aims: 1) effectively engage investigators throughout WV by providing traditional services in biostatistics and epidemiology, 2) implement cutting-edge tools and methods in biostatistics and epidemiology, with a particular focus on the needs of WV researchers, and 3) disseminate current and classical information in biostatistics and epidemiology. Statistics assistance will be provided to researchers via one-on-one consulting as well as walk-in clinics. Given the distance between institutions in WV, these consultations can occur either in-person or via phone, e-mail, Skype, etc. New methods for designing studies and analyzing data will focus on those most relevant to West Virginia and include adaptive response designs, predictive modeling, and clinical and population health epidemiology, making use of new data linkage capabilities. Methods focused on the conduct of “real world” studies that can be conducted quickly and have a direct and immediate impact on the citizens of West Virginia will also be a major priority of this Core. To help achieve this goal, experts from throughout the United States will be invited to share their expertise with WV statisticians who can then apply these methods to locally collected data. To enhance the statistical knowledge base in WV, statisticians included in this project will offer seminars and workshops to investigators conducting research in WV. CRDEB faculty will also provide instruction in certificate and degree programs aimed at improving the research capacity in West Virginia. The ultimate goal of all of these activities is improving the health of all West Virginians.

西方临床研究设计、流行病学和生物统计学（CRDEB）核心的总体目的 弗吉尼亚临床和转化科学研究所（WVCTSI）将为整个西弗吉尼亚州的研究人员提供 弗吉尼亚州（西弗吉尼亚州），具有集中协调的分析支持手段。这些专业知识将由 一组科学家，他们共同带来了从一般到高度专业化的一整套综合技能 生物统计学和流行病学方面的专门知识。其目标是使研究人员能够严格解决WVCTSI 优先保健领域，包括：成瘾和新出现的流行病（例如，丙型肝炎）、癌症、心血管 疾病和慢性肺病。我们提出以下三个具体目标：1）有效参与 通过提供生物统计学和流行病学方面的传统服务，2）实施 生物统计学和流行病学方面的尖端工具和方法，特别关注WV的需求 研究人员，和3）传播生物统计学和流行病学的当前和经典信息。统计 将通过一对一咨询和无预约诊所向研究人员提供援助。考虑到距离 在西弗吉尼亚州的机构之间，这些协商可以亲自进行，也可以通过电话、电子邮件、Skype等进行。 设计研究和分析数据的方法将集中在那些与西弗吉尼亚州最相关的方法上，包括 适应性反应设计，预测建模，临床和人口健康流行病学，利用 新的数据连接能力。方法侧重于开展“真实的世界”研究， 迅速并对西弗吉尼亚州的公民产生直接和直接的影响也将是一个主要的优先事项， 这个核心。为了帮助实现这一目标，来自美国各地的专家将被邀请分享他们的 西弗吉尼亚州统计人员的专业知识，然后可以将这些方法应用于当地收集的数据。增强 在西弗吉尼亚州的统计知识库中，参与该项目的统计人员将举办研讨会和讲习班， 调查人员在西弗吉尼亚州进行研究。CRDEB教师还将提供证书和学位课程 该项目旨在提高西弗吉尼亚州的研究能力。所有这些活动的最终目标 正在改善所有西弗吉尼亚人的健康状况