2021 Lung Development, Injury and Repair Gordon Research Conference and Gordon Research Seminar
2021年肺发育、损伤与修复戈登研究会议暨戈登研究研讨会
基本信息
- 批准号:10217714
- 负责人:
- 金额:$ 1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-06-10 至 2022-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAreaAsthmaAutomobile DrivingBiologicalBiologyBiomedical EngineeringCOVID-19 pandemicCareer MobilityCellsCellular biologyCessation of lifeChronicChronic Obstructive Airway DiseaseChronic lung diseaseClinicalCollaborationsDataDevelopmentDiagnosisDisabled PersonsDiseaseEarly DiagnosisEnsureFacultyFosteringFundingGenderGeographyGrowthHealthInjuryInvestmentsLong COVIDLungLung diseasesMedicineMentorsMolecularMolecular BiologyPhysiciansPhysiologyPopulationPositioning AttributePostdoctoral FellowPulmonary FibrosisRaceResearchResearch PersonnelRoleSARS-CoV-2 infectionScientistSenior ScientistStructureTherapeuticTimeTissuesTranslatingTranslationsUnderrepresented MinorityViralWomanWorld Health Organizationcareercohortexperiencegraduate studenthuman diseaseinjury and repairknowledge integrationlung developmentlung injurymeetingsnext generationnovelpeerpeer networksprematurepulmonary functionrepairedrespiratoryrestorationsevere injurysymposiumtranslational scientist
项目摘要
Project Summary:
The 2021 Lung Development, Injury and Repair Gordon Research Conference (GRC) and associated Gordon
Research Seminar (GRS) will be held August 14-20, 2021 in Waterville Valley, NH. The theme for the 2021
Lung GRC is "Biological Discoveries to Transform Respiratory Medicine". This meeting comes at a critical time,
as the prolonged consequences of severe lung injuries associated with the COVID-19 pandemic will be coming
into focus, heightening our need to understand, and ultimately counteract, the dysfunctional repair and
remodeling that follows severe injury. Moreover, the growing global burden of lung disease continues
unabated, with some 4 million premature deaths annually worldwide attributed to chronic respiratory diseases,
including COPD, asthma, and pulmonary fibrosis, according to the World Health Organization. While
investments in basic scientific research continue to accelerate substantial strides forward in understanding
molecular, cellular and tissue level mechanisms driving respiratory diseases, translation of these findings
toward early detection and effective repair and restoration of lung function in chronic respiratory diseases
remains a major barrier. Meeting this challenge requires the integration of knowledge from experts spanning
lung development, molecular and cell biology, physiology, bioengineering, matrix biology as well as physicians
and translational experts immersed in the diagnosis and treatment of human disease. This conference will
bring this diversity of expertise together to disseminate and debate the latest findings in the fields of lung
development, injury and repair, and to formulate the new ideas, collaborations and approaches that will be
needed to translate biologic discoveries toward meaningful advances in respiratory medicine. A major
emphasis of the Lung GRC and GRS is to strengthen the pipeline of scientists and clinicians focused on lung
development, injury and repair. Funds from this R13 will be specifically targeted to promote participation in the
conference by women, under-represented minorities and people with disabilities, particularly graduate
students, postdoctoral fellows, and early career investigators. The unique attributes of the GRC (small,
secluded, unpublished data, abundant time for discussion) and GRS (close trainee interactions with peers and
seniors) formats provide an opportunity for formal and informal interactions and collaborations that are likely to
have significant and sustained impact on the field. The Lung Development, Injury and Repair GRC/GRS will
thus promote accelerated progress in understanding and treating chronic lung diseases, and help to ensure the
vitality and growth of a diverse pipeline of clinicians and scientists capable of addressing the growing burden of
lung diseases.
项目概要:
2021年肺发育,损伤和修复戈登研究会议(GRC)和相关的戈登
研究研讨会(GRS)将于2021年8月14日至20日在沃特维尔山谷,NH举行。2021年的主题
肺GRC是“改变呼吸医学的生物发现”。这次会议是在一个关键时刻召开的,
由于与COVID-19大流行相关的严重肺损伤的长期后果即将到来,
聚焦,提高我们理解的需要,并最终抵消,功能失调的修复,
严重损伤后的重塑。此外,全球肺部疾病的负担仍在继续增加,
全球每年约有400万人因慢性呼吸道疾病而过早死亡,
包括慢性阻塞性肺病、哮喘和肺纤维化。而
对基础科研的投资继续加速认识的重大进步
分子、细胞和组织水平的机制驱动呼吸系统疾病,这些发现的转化
致力于慢性呼吸系统疾病的早期检测和有效修复及肺功能恢复
仍然是一个主要障碍。应对这一挑战需要整合来自不同领域的专家的知识,
肺发育,分子和细胞生物学,生理学,生物工程,基质生物学以及医生
以及致力于人类疾病诊断和治疗的翻译专家。本次大会将
将这种多样性的专业知识聚集在一起,传播和辩论肺部领域的最新发现,
发展,损伤和修复,并制定新的想法,合作和方法,将
需要将生物学发现转化为呼吸医学的有意义的进步。一个主要
肺GRC和GRS的重点是加强专注于肺的科学家和临床医生的管道
发育、损伤和修复。R13的资金将专门用于促进参与
妇女、代表人数不足的少数民族和残疾人,特别是研究生
学生、博士后研究员和早期职业调查人员。GRC的独特属性(小,
隐蔽的、未发表的数据、充足的讨论时间)和GRS(学员与同行的密切互动,
老年人)的形式提供了一个机会,正式和非正式的互动和合作,可能会
对实地产生重大和持续的影响。肺发育、损伤和修复GRC/GRS将
从而促进对慢性肺部疾病的理解和治疗的加速进展,并有助于确保
一个多样化的临床医生和科学家管道的活力和增长,能够解决日益增长的负担,
肺部疾病
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Daniel J. Tschumperlin其他文献
788 – Microrna Let-7F is Overexpressed in Colonic Smooth Muscle from Patients with Slow Transit Constipation, Reduces Voltage-Gated Sodium Channel Na<sub>v</sub>1.5 Current Density and Gastrointestinal Smooth Muscle Contractility
- DOI:
10.1016/s0016-5085(19)37205-1 - 发表时间:
2019-05-01 - 期刊:
- 影响因子:
- 作者:
Amelia Mazzone;Peter R. Strege;Constanza Alcaino;Andrew J. Haak;Daniel J. Tschumperlin;Mona El Refaey;Peter J. Mohler;Yujiro Hayashi;Tamas Ordog;Stefan S. Calder;Peng Du;Simon J. Gibbons;Gianrico Farrugia;Arthur Beyder - 通讯作者:
Arthur Beyder
EVALUATION OF THE IN VIVO EFFICACY OF THE JAK INHIBITOR AZD1480 AGAINST UTERINE LEIOMYOMAS IN A PATIENT-DERIVED XENOGRAFT MOUSE MODEL
- DOI:
10.1016/j.fertnstert.2023.05.015 - 发表时间:
2023-07-01 - 期刊:
- 影响因子:
- 作者:
Michael F. Neblett;Merrick T. Ducharme;Jeffrey A. Meridew;Andrew J. Haak;Daniel J. Tschumperlin;Elizabeth A. Stewart - 通讯作者:
Elizabeth A. Stewart
SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis
SOCS 结构域靶向肺成纤维细胞和实验性肺纤维化中的细胞外基质组装
- DOI:
10.1038/s41598-024-83187-9 - 发表时间:
2024-12-30 - 期刊:
- 影响因子:3.900
- 作者:
Carina Magdaleno;Daniel J. Tschumperlin;Narendiran Rajasekaran;Archana Varadaraj - 通讯作者:
Archana Varadaraj
Daniel J. Tschumperlin的其他文献
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{{ truncateString('Daniel J. Tschumperlin', 18)}}的其他基金
Fibrogenic activation and memory in the lung mesenchyme
肺间质的纤维化激活和记忆
- 批准号:
10558822 - 财政年份:2022
- 资助金额:
$ 1万 - 项目类别:
Therapeutic ECM Resorption in Cellular Systems and Precision Cut Lung Slices.
细胞系统中的治疗性 ECM 吸收和精密切割肺切片。
- 批准号:
10530660 - 财政年份:2020
- 资助金额:
$ 1万 - 项目类别:
Therapeutic ECM Resorption in Cellular Systems and Precision Cut Lung Slices.
细胞系统中的治疗性 ECM 吸收和精密切割肺切片。
- 批准号:
10318078 - 财政年份:2020
- 资助金额:
$ 1万 - 项目类别:
Therapeutic ECM Resorption in Cellular Systems and Precision Cut Lung Slices.
细胞系统中的治疗性 ECM 吸收和精密切割肺切片。
- 批准号:
10025548 - 财政年份:2020
- 资助金额:
$ 1万 - 项目类别:
Screening Fibroblast-Matrix Stiffness Interactions to ID New Fibrosis Therapies
筛选成纤维细胞-基质硬度相互作用以识别新的纤维化疗法
- 批准号:
8445051 - 财政年份:2013
- 资助金额:
$ 1万 - 项目类别:
Screening Fibroblast-Matrix Stiffness Interactions to ID New Fibrosis Therapies
筛选成纤维细胞-基质硬度相互作用以识别新的纤维化疗法
- 批准号:
8712545 - 财政年份:2013
- 资助金额:
$ 1万 - 项目类别:
Epithelial-Mesenchymal Interactions in Fibrosis Resolution
纤维化消退中的上皮-间质相互作用
- 批准号:
10655172 - 财政年份:2009
- 资助金额:
$ 1万 - 项目类别:
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