Core 1. Bioinformatics and statistics.
Core 1. Bioinformatics and statistics.
核心1.生物信息学和统计学。
批准号：
10223111
负责人：
Patrik D'haeseleer
金额：
$10.73万
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
项目状态：
已结题
起止时间：
2019-08-08 至 2024-07-31
关键词：
Amino Acid SequenceBioinformaticsBiologicalBiometryChlamydia trachomatisCodeCollaborationsComplexComputational BiologyComputer AnalysisConsultationsCryoelectron MicroscopyDataData AnalysesData ReportingEpitopesEscherichia coliEvolutionGeneticGoalsHealthImmunologyIn VitroInfectionInvestmentsKnowledgeMapsMeasuresMembrane ProteinsOutcomePathogenesisPreclinical TestingProceduresProcessProtein EngineeringProteinsResearch DesignResearch Project GrantsSequence AlignmentServicesStatistical Data InterpretationStatistical MethodsStructural ModelsSynthetic VaccinesSystemTestingTranslatingTranslationsVaccinesWorkbasecomparativedesigndesign and constructionefficacy outcomesexperimental studyfirst-in-humanin vivoinnovationmajor outer membrane proteinnanonanolipoprotein particlesnoveloverexpressionpreclinical trialpressureprotein expressionsafety outcomesscaffoldstatisticssuccesstechnology developmentthree dimensional structurevaccine evaluation
中文摘要
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英文摘要
Bioinformatics and Statistics Core 1. ABSTRACT: The Center's overall scientific goal is to develop,
validate, and perform pre-clinical testing of a suite of NanoScaffold-based Chlamydia trachomatis (Ct)
vaccines. Successful pre-clinical trials would translate to first-in-human studies, with the potential to mitigate
the health effects associated with Ct infection. The Bioinformatics and Statistics Core (BSC) will support the
Center's goals by providing design and analysis leading to rigorous quantitative assessment of each step of the
in vitro and in vivo studies carried out in Projects 1, 2, and 3, in close collaboration with the Immunology Core.
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Core 1. Bioinformatics and statistics.
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批准号：10458651
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项目类别：
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资助金额：$10.91万
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财政年份：2019
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负责人：Patrik D'haeseleer
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依托单位：
海外基金
