Core A: Administrative Core

核心A.行政核心：摘要 ‘在反弹期间恢复蓄水池’(R3)管理核心的任务是提供 对我们的项目进行领导、协调和战略规划，使我们的愿景成为现实。R3 该计划将是一项大型合作科学努力，涉及加州大学的研究人员和工作人员 加州大学圣地亚哥分校(UCSD)、哈佛、布里格姆妇女医院和苏黎世大学。因此， 管理核心旨在： 目标1.在行政协调和科学沟通方面提供有效领导 该计划的机构、调查人员、工作人员和社区。 目标2.提供必要的科学和行政协调以及加强各国之间的沟通 项目调查人员、工作人员、社区和NIH。 目标3.利用现有的当地资源，使当地艾滋病毒感染者和受影响社区参与 程序研究。 目标4.有效管理所有财务和基础设施资源，并监督和评估 所有方案组成部分的绩效，包括行政、报告、实验室、药房、监管 保证、数据管理、质量管理和工作人员培训。 目标5.在整个项目中培养自我评估、自我改进和战略规划。 目标6.向计划内外的相关合作伙伴制定明确的报告程序，包括 伦理委员会(EC)、社区咨询委员会(CAB)、国立卫生研究院(NIH)、方案 调查人员和工作人员。还要确保及时和适当地向科学文献报告结果。 为了实现这些目标，行政核心将由一支经验丰富的团队组成，包括 首席调查员、项目经理、财务经理、监管专家和信息 技术专家。这些人员将共同确保拟议的R3顺利和透明地运行 程序。

Core A. Administrative Core: Abstract The mission of the `Revealing Reservoirs during Rebound' (R3) Administrative Core is to provide the leadership, coordination and strategic planning for our program so that our vision becomes reality. The R3 program will be a large collaborative scientific effort involving investigators and staff at the University of California San Diego (UCSD), Harvard, Brigham and Women's Hospital, and University of Zurich. Thus, the Administrative Core is designed to: Aim 1. Provide effective leadership in the administrative coordination and scientific communication across institutions, investigators, staff, and communities of the program. Aim 2. Deliver essential scientific and administrative coordination and enhanced communication among program investigators, staff, community, and NIH. Aim 3. To leverage existing local resources to engage local HIV –infected and –affected communities in program research. Aim 4. Effectively manage all financial and infrastructure resources, and oversee and evaluate the performance of all program components, including administration, reporting, laboratory, pharmacy, regulatory assurance, data management, quality management and staff training. Aim 5. Cultivate self-evaluation, self-improvement, and strategic planning across the program. Aim 6. Develop clear reporting procedures to relevant partners within and outside the program, including Ethics Committee (EC), Community Advisory Board (CAB), National Institutes of Health (NIH), program investigators, and staff. Also ensure timely and appropriate reporting of results to the scientific literature. To accomplish these aims, the Administrative Core will be comprised of a highly experienced team, including the principal investigator, a program manager, a fiscal manager, a regulatory specialist and an information technologist. Together, these individuals will ensure the smooth and transparent operation of the proposed R3 program.