SD CFAR EHE IS Consultation Hub

项目概要/摘要 圣地亚哥艾滋病研究中心（SD CFAR）的使命是推动艾滋病毒的发现， 圣地亚哥研究人员的前沿研究，以改善艾滋病毒感染者的生活，并阻止新的 感染，包括本地和全球。我们中心的研究重点与NIH艾滋病办公室保持一致 研究优先事项包括预防新的感染，优化艾滋病毒护理和开发治疗方法， 促进艾滋病毒感染者和高危人群的健康公平。 SD CFAR的具体目标是： 1.通过为跨领域的高效协作提供基础，加快发现的步伐， 调查人员、成员机构和艾滋病毒社区。 2.利用我们的社区参与和国际伙伴关系来发展可持续研究 可以为政策、实践和实施提供信息的计划。 3.为当地和国际研究者提供培训、启发、指导和专家指导（TIME） 跨职业阶段。 4.为CFAR成员机构、调查人员和我们的整个团队提供科学和行政领导 地区 结构：SD CFAR是多机构的，成员来自拉霍亚过敏和免疫学研究所（LJI）， 圣地亚哥州立大学（SDSU）、斯克里普斯研究所（SR）和加州圣地亚哥大学（UCSD）。 该中心由我们的运营团队成员共同指导，包括Davey Smith博士（联系PI）、道格拉斯博士 Richman，Sonia Jain，Dennis Burton，and Jamila Stockman（Leadership Trainee）.我们的CFAR包括 八个核心和一个科学工作组。我们也继续接受我们的咨询委员会的指导， 作为我们的联合董事，核心董事，科学工作组和我们的会员。 进展：自2017年更新以来，SD CFAR的努力已经产生了一个富有成效和不断增长的群体， 其研究工作从阻碍HIV复制的细胞限制因子， 传播到行为方法，以改善预防和治疗。我们资助的研究基地 保持在Tier 3的地位，并在18 - 21财年之间稳步增长了1190万美元。此外，还有870 在过去的一个周期中，CFAR支持的出版物比上次更新增加了44.5%。我们仍然 致力于支持催化多学科研究，从实验室工作台， 患者床边，同时培养新一代的创新，独立的研究人员。

Overall Project Summary/Abstract The mission of the San Diego Center for AIDS Research (SD CFAR) is to drive HIV discoveries and foster cutting-edge research by San Diego investigators to improve the lives of people with HIV and to stop new infections, both locally and globally. Our Center’s research priorities are aligned with the NIH Office of AIDS Research priorities and include preventing new infections, optimizing HIV care, and developing a cure, while promoting health equity for people with and at risk for HIV. The specific aims of the SD CFAR are to: 1. Accelerate the pace of discovery by providing the foundation for productive collaborations across fields, investigators, member institutions, and the HIV community. 2. Capitalize on our community engagement and international partnerships to develop sustainable research programs that can inform policy, practice, and implementation. 3. Provide Training, Inspiration, Mentoring, and Expert guidance (TIME) to local and international investigators across career stages. 4. Provide scientific and administrative leadership to CFAR member institutions, investigators, and across our region. Structure: The SD CFAR is multi-institutional, with members at La Jolla Institute of Allergy and Immunology (LJI), San Diego State University (SDSU), Scripps Research (SR), and University of California San Diego (UCSD). The Center is co-directed by members of our Operations Team including Drs. Davey Smith (contact PI), Douglas Richman, Sonia Jain, Dennis Burton, and Jamila Stockman (Leadership Trainee). Our CFAR is comprised of eight Cores and one Scientific Working Group. We continue to be guided by our Advisory Committees, as well as our Co-Directors, Core Directors, Scientific Working Groups, and our membership. Progress: Since our renewal in 2017, SD CFAR efforts have yielded a productive and growing group of investigators whose research work extends from cellular restriction factors that impede HIV replication and transmission to behavioral approaches to improve prevention and treatment. Our funded research base remained at Tier 3 status and steadily increased by $11.9M between FY18 - 21. Further, there have been 870 CFAR-supported publications this past cycle, representing a 44.5% increase since the last renewal. We remain committed to supporting catalytic multidisciplinary research, bringing breakthroughs from laboratory bench to patient bedside, while fostering a new generation of innovative, independent investigators.