SD CFAR EHE IS Consultation Hub

总体项目摘要/摘要 圣地亚哥艾滋病研究中心(SD CFAR)的使命是推动艾滋病毒的发现和促进 圣地亚哥调查人员开展尖端研究，以改善艾滋病毒感染者的生活并阻止新的 当地和全球的感染。我们中心的研究重点与美国国立卫生研究院艾滋病办公室保持一致 研究优先事项，包括预防新感染、优化艾滋病毒护理和开发治疗方法，同时 促进艾滋病毒携带者和高危人群的健康公平。 可持续发展CFAR的具体目标是： 1.通过为跨领域的富有成效的协作提供基础，加快发现的步伐 调查人员、成员机构和艾滋病毒社区。 2.利用我们的社区参与和国际伙伴关系来发展可持续的研究 可以为政策、实践和实施提供信息的计划。 3.向当地和国际调查人员提供培训、灵感、指导和专家指导(时间) 在职业生涯的各个阶段。 4.为CFAR成员机构、调查人员和整个我们的 区域。 结构：SD CFAR是多机构的，成员在拉霍亚过敏和免疫学研究所(LJI)， 圣地亚哥州立大学(SDSU)、斯克里普斯研究(SR)和加州大学圣地亚哥分校(UCSD)。 该中心由我们运营团队的成员共同指导，包括Douglas的Davey Smith博士(联系Pi) 理曼、索尼娅·贾恩、丹尼斯·伯顿和贾米拉·斯托克曼(领导力实习生)。我们的CFAR包括 八个核心和一个科学工作组。我们也继续受到我们的咨询委员会的指导 作为我们的联席董事、核心董事、科学工作组和我们的成员。 进展：自2017年我们续签以来，SD CFAR的努力产生了一批富有成效且不断增长的 研究人员的研究工作从阻碍艾滋病毒复制的细胞限制因素和 传播到行为方法，以改善预防和治疗。我们资助的研究基地 保持在Tier 3状态，并在18-21财年期间稳步增长1190万美元。此外，已经有870个 在上一个周期中，CFAR支持的出版物增加了44.5%，比上次续订增加了44.5%。我们会留下来 致力于支持催化多学科研究，实现从实验室到实验室的突破 患者身边，同时培养新一代创新的独立调查人员。

Overall Project Summary/Abstract The mission of the San Diego Center for AIDS Research (SD CFAR) is to drive HIV discoveries and foster cutting-edge research by San Diego investigators to improve the lives of people with HIV and to stop new infections, both locally and globally. Our Center’s research priorities are aligned with the NIH Office of AIDS Research priorities and include preventing new infections, optimizing HIV care, and developing a cure, while promoting health equity for people with and at risk for HIV. The specific aims of the SD CFAR are to: 1. Accelerate the pace of discovery by providing the foundation for productive collaborations across fields, investigators, member institutions, and the HIV community. 2. Capitalize on our community engagement and international partnerships to develop sustainable research programs that can inform policy, practice, and implementation. 3. Provide Training, Inspiration, Mentoring, and Expert guidance (TIME) to local and international investigators across career stages. 4. Provide scientific and administrative leadership to CFAR member institutions, investigators, and across our region. Structure: The SD CFAR is multi-institutional, with members at La Jolla Institute of Allergy and Immunology (LJI), San Diego State University (SDSU), Scripps Research (SR), and University of California San Diego (UCSD). The Center is co-directed by members of our Operations Team including Drs. Davey Smith (contact PI), Douglas Richman, Sonia Jain, Dennis Burton, and Jamila Stockman (Leadership Trainee). Our CFAR is comprised of eight Cores and one Scientific Working Group. We continue to be guided by our Advisory Committees, as well as our Co-Directors, Core Directors, Scientific Working Groups, and our membership. Progress: Since our renewal in 2017, SD CFAR efforts have yielded a productive and growing group of investigators whose research work extends from cellular restriction factors that impede HIV replication and transmission to behavioral approaches to improve prevention and treatment. Our funded research base remained at Tier 3 status and steadily increased by $11.9M between FY18 - 21. Further, there have been 870 CFAR-supported publications this past cycle, representing a 44.5% increase since the last renewal. We remain committed to supporting catalytic multidisciplinary research, bringing breakthroughs from laboratory bench to patient bedside, while fostering a new generation of innovative, independent investigators.