Interdepartmental Training in Pharmacological Sciences
药理学科学跨部门培训
基本信息
- 批准号:10397983
- 负责人:
- 金额:$ 62.44万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-07-01 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
This new application requests support for the newly re-designed University of Michigan (U-M) Pharmacological
Sciences Training Program (PSTP). The goal of the PSTP is to develop a diverse pool of well-trained biomedical
scientists who have the technical, operational and professional skills to conduct pharmacological research in an
ethically responsible and rigorous manner, and to enter diverse careers in the biomedical research
workforce. Annual support for 12 trainees (6-Year 2 and 6-Year 3 Trainees in any one year) is requested
throughout the five years of funding. The U-M PSTP is a long-standing collaboration between the Medical School
and the College of Pharmacy that provides synergistic, translational education, research training, and career
development for pre-doctoral trainees in four degree-granting programs: Pharmacology, Biological Chemistry,
Medicinal Chemistry, and Pharmaceutical Sciences. The new, competency-based PSTP curriculum, which
includes an experiential program in Real-World Drug Discovery, is designed to provide trainees with a strong
foundational understanding of the pharmacological sciences, to provide training in the performance of rigorous
and reproducible research, and to provide career development, teamwork, and leadership training, all under the
direction of well-trained and dedicated faculty mentors. An extensive and successful alumni base provides
career mentorship, networking, and future employment opportunities. PSTP mentors encourage trainees to think
broadly about research problems in human disease while focusing their thesis research on a critical, unmet gap
in knowledge using rigorous experimental design and methods. This re-designed strong, interdisciplinary, yet
individualized, training in the pharmacological sciences will give trainees a distinct advantage in that they will be
rapidly employable and well positioned to contribute to the NIH mission to discover new medicines. The
development of novel and effective therapeutic agents is a critical, on-going global need that requires rigorously
trained, innovative team players to solve critical problems in health care. It is essential that the US continue to
produce doctoral-level scientists from diverse backgrounds with broad training in pharmacological sciences and
experimental therapeutics who understand basic science and translational medicine. U-M is a premiere
institution in research and training of graduate students in the biomedical sciences on a global scale. Although
U-M has individual graduate programs in the Departments associated with this training program, the PSTP is
the only program at U-M that draws upon the expertise of faculty, alumni, the Michigan Drug Discovery Institute,
and the enthusiasm of students across these units to fertilize interdisciplinary education, collaborative research,
career development, and team-based approaches to innovation and translation in target discovery and
development of experimental therapeutics.
这个新的应用程序要求支持新重新设计的密歇根大学药理学
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Lori L. Isom其他文献
I. Cellular and molecular biology of sodium channel beta-subunits: therapeutic implications for pain?
I. 钠通道 β 亚基的细胞和分子生物学:对疼痛的治疗意义?
- DOI:
- 发表时间:
2000 - 期刊:
- 影响因子:0
- 作者:
Lori L. Isom - 通讯作者:
Lori L. Isom
Na+ channel subunits and Ig domains
钠离子通道亚单位和免疫球蛋白结构域
- DOI:
10.1038/383307b0 - 发表时间:
1996-09-26 - 期刊:
- 影响因子:48.500
- 作者:
Lori L. Isom;William A. Catterall - 通讯作者:
William A. Catterall
Modulation of Kv1 Voltage-Gated Potassium Channels by Sodium Channel Beta Subunits
- DOI:
10.1016/j.bpj.2011.11.3733 - 发表时间:
2012-01-31 - 期刊:
- 影响因子:
- 作者:
Hai M. Nguyen;Jeffrey D. Calhoun;Lori L. Isom;Alan L. Goldin;George K. Chandy - 通讯作者:
George K. Chandy
Dramatic Improvement in Seizures With Phenytoin Treatment in an Individual With Refractory Epilepsy and a <em>SCN1B</em> Variant
- DOI:
10.1016/j.pediatrneurol.2020.03.012 - 发表时间:
2020-07-01 - 期刊:
- 影响因子:
- 作者:
Louis T. Dang;Shane C. Quinonez;Bridget R. Becka;Lori L. Isom;Sucheta M. Joshi - 通讯作者:
Sucheta M. Joshi
Dlg1 gene expression and sexual dimorphism in regulation of heart rate and its variability in a murine model
- DOI:
10.1016/j.bpj.2023.11.2358 - 发表时间:
2024-02-08 - 期刊:
- 影响因子:
- 作者:
Danyal Raza;Shoaib Siddiqui;Ivan Kalla;Roberto Mondragon;Oluwadamola Olaiya;Erika Anderson;Lori L. Isom;Omer Berenfeld;Justus M. Anumonwo - 通讯作者:
Justus M. Anumonwo
Lori L. Isom的其他文献
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{{ truncateString('Lori L. Isom', 18)}}的其他基金
Development and Validation of a Transgenic Rabbit Model of Dravet Syndrome
Dravet 综合征转基因兔模型的开发和验证
- 批准号:
10574719 - 财政年份:2023
- 资助金额:
$ 62.44万 - 项目类别:
Interdepartmental Training in Pharmacological Sciences
药理学科学跨部门培训
- 批准号:
10616678 - 财政年份:2021
- 资助金额:
$ 62.44万 - 项目类别:
Cardiac Mechanisms of Sudden Unexpected Death in Epilepsy
癫痫猝死的心脏机制
- 批准号:
10454393 - 财政年份:2020
- 资助金额:
$ 62.44万 - 项目类别:
Epilepsy Multiplatform Variant Prediction (EpiMVP) - Admin Core
癫痫多平台变异预测 (EpiMVP) - 管理核心
- 批准号:
10670354 - 财政年份:2020
- 资助金额:
$ 62.44万 - 项目类别:
Development of a Rabbit Model of SCN1A-linked Dravet Syndrome
SCN1A 相关 Dravet 综合征兔模型的开发
- 批准号:
10062010 - 财政年份:2020
- 资助金额:
$ 62.44万 - 项目类别:
Cardiac Mechanisms of Sudden Unexpected Death in Epilepsy
癫痫猝死的心脏机制
- 批准号:
10661021 - 财政年份:2020
- 资助金额:
$ 62.44万 - 项目类别:
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