Pacific High Schools STEP-UP to Biomedical Research

项目摘要 位于马诺阿的夏威夷大学提议继续发展太平洋加强方案， 研究培训和指导，以代表性不足的少数民族和处境不利的高中学生， 夏威夷州和美国在太平洋的领土：美属萨摩亚、关岛、英联邦 北方马里亚纳群岛、密克罗尼西亚联邦、马歇尔群岛共和国和 帕劳共和国。在过去的5年里，太平洋STEP-UP已经招收了145名实习生， NIDDK STEP-UP暑期课程，并在2015年期间让另外414名学生接触实验室科学。 学校岁月。我们在太平洋学院建立了实验室研究能力（包括人员培训） 在我们之前没有人。我们从2005年开始跟踪了270多名STEP-UP校友，发现 绝大多数人接受了以科学为重点的大学教育，许多人还寻求研究生教育。 培训和终端学位。迄今为止，太平洋STEP-UP仍然是唯一正式的研究培训 美国太平洋地区的高中生计划，迫切需要建立和培养一个管道， 寻求健康研究职业的人数不足的个人，以消除该地区的健康差距 of the world.我们相信Pacific STEP-UP已在该地区扎根，我们将继续 发展和扩大我们的STEP-UP研究培训和指导计划。此外，新战略和 将采用培训和指导以及能力建设的方法，进一步扩大STEP-UP的范围， 太平洋社区。目标是在提供NIDDK授权研究的过程中 通过培训/指导，我们的计划将提高社区对相关健康问题和未来的认识 在“本土”的医疗保健研究人员的价值观，从而吸引与健康有关的研究的支持。 Pacific STEP-UP旨在培养和塑造一种重视科学研究的文化， 这些社区的健康问题。因此，我们提出三个具体目标。1.招聘最优秀的人才 来自美国太平洋七个州和地区的高中生（11年级和12年级）进入 加强夏季研究计划，并跟踪队列的学术进步至少5年。2. 提供个性化的暑期研究经验（以及相关的教育和培训），强调当地 社区或人口的相关性，以太平洋加强实习生。为STEP-UP校友提供后续服务， 以研究为重点，指导为期9个月。3.在实验室培养兴趣 在太平洋高中的科学，同时加强当地学院的能力，使和维持实验室 和基于社区的研究;所有这些都是为了支持太平洋加强培训计划， 应用池和研究机会。

PROJECT SUMMARY The University of Hawaii at Manoa proposes to continue to develop the Pacific STEP-UP Program to provide research training and mentoring to underrepresented minority and disadvantaged high school students in the State of Hawaii, and the US Territories in the Pacific: American Samoa, Guam, the Commonwealth of the Northern Mariana Islands, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau. For the past 5 years, Pacific STEP-UP has enrolled trained 145 student interns in the NIDDK STEP-UP summer program, and exposed another 414 students to laboratory sciences during the school years. We built the capacity for laboratory research in the Pacific colleges (including personnel training) where there were none before us. We tracked over 270 STEP-UP alumni from as early as 2005 to find that a great majority pursued college education with a science emphasis, and many also sought post-graduate training and terminal degrees. To date, Pacific STEP-UP remains the only formalized research training program for high school students in the US Pacific, amid the urgent need to build and foster a pipeline of underrepresented individuals seeking health research careers in order to combat health disparity in this region of the world. With confidence that Pacific STEP-UP has established roots in the region, we will continue to develop and expand our STEP-UP research training and mentoring program. Moreover, new strategies and approach in training and mentoring, as well as in capacity building will be used to further STEP-UP's reach into the Pacific communities. The goal is that in the process of providing the NIDDK mandated research training/mentoring, our Program will raise community awareness of relevant health issues and of the future values in the “home-grown” healthcare researchers; thereby drawing support for health-related research. Pacific STEP-UP aims to seed and shape a culture that values scientific research as the means to address health issues in these communities. Accordingly, we propose three Specific Aims. 1. Recruit best qualified high school students (11th and 12th graders) from the seven US State and Territories in the Pacific into the STEP-UP Summer Research Program, and track the cohort's academic progress for a minimum of 5 years. 2. Provide individualized summer research experience (and related education and training) that stresses local community or population relevance to the Pacific STEP-UP interns. Provide STEP-UP alumni with follow up, and research-focused, mentoring extending for 9 months. 3. Seed and cultivate interests in laboratory sciences in the Pacific high schools while strengthen local colleges' capacity to enable and sustain laboratory and community based research; all in support of the Pacific STEP-UP training program by expanding the application pool and research opportunities.