Pacific High Schools STEP-UP to One Health

项目摘要 约翰A。夏威夷大学伯恩斯医学院提出继续开发太平洋 向代表性不足和处境不利的高等教育机构提供研究培训和指导的STEP-UP方案 夏威夷州和美国在太平洋的六个附属领土（E区）的学校学生。为 在过去的5年里，太平洋STEP-UP已经招收了104名学生参加NIDDK STEP-UP暑期课程， 在学年中让其他学生接触实验室科学。我们继续建设能力， 在太平洋学院的实验室研究，在我们之前没有。我们追踪了375名STEP-UP校友 早在2005年，我们就发现大多数人追求的是以科学为重点的大学教育， 还寻求研究生培训和最终学位。太平洋STEP-UP仍然是唯一正式的手- 在美国太平洋地区的高中研究培训计划，在迫切需要建立和培养一个 寻求健康研究职业的代表性不足的个人的管道，以消除健康差距， 世界的这个地区。我们相信Pacific STEP-UP已在该地区扎根， 继续我们的研究培训和指导计划，但在一个框架下制定新的课程 健康在研究培训、指导和能力建设方面的新战略和方法将进一步 NIDDK STEP-UP通过提高人们对太平洋地区相互依存关系的认识， 人类、动物和生态环境的福祉;及其对健康相关问题的影响。目标是 培育和塑造一种文化，将One Health研究视为解决相关健康问题的手段 在这些社区，培养一批“土生土长”的科学家，准备研究解决方案。做 因此，我们将完成NIDDK的STEP-UP使命，建立一个未来科学家的管道，并使其多样化， 从跨部门和跨部门的多个角度解决与NIDDK有关的健康和疾病问题， 在一个健康下的纪律方法。因此，我们提出三个具体目标。（一）.招聘最佳 来自美国太平洋地区七个州和地区的合格高中生（11年级和12年级）进入 加强夏季研究计划，并跟踪队列的学术进展至少5 年（二）、提供个性化的研究经验（以及相关的教育和培训），强调一个 健康方法和当地社区或人口相关性。为STEP-UP校友提供跟进，以及 以研究为重点，指导为期9个月。（三）、种子和培养利益在一个健康的高 学校的学生，同时加强地方学院的能力，使实验室，实地和社区为基础的 研究重点是一个健康概念，所有这些都是为了支持太平洋STEP-UP计划， 申请库和研究机会，并加强研究培训计划。

PROJECT SUMMARY The John A. Burns School of Medicine of the University of Hawaii proposes to continue to develop the Pacific STEP-UP Program to provide research training and mentoring to underrepresented and disadvantaged high school students in the State of Hawaii, and the six US and US affiliated territories in the Pacific (Region E). For the past 5 years, Pacific STEP-UP has enrolled 104 students in the NIDDK STEP-UP summer program, and exposed other students to laboratory sciences during the school year. We continued to build capacity for laboratory research in the Pacific colleges where there was none before us. We tracked 375 STEP-UP alumni from as early as 2005 to find that a majority pursued college education with a science emphasis, and many also sought post-graduate training and terminal degrees. Pacific STEP-UP remains the only formalized hands- on research training program for high schools in the US Pacific, amid the urgent need to build and foster a pipeline of underrepresented individuals seeking health research careers in order to combat health disparity in this region of the world. With confidence that Pacific STEP-UP has established roots in the region, we will continue our research training and mentoring program but charting a new course under framework of One Health. The new strategy and approach in research training, mentoring, and in capacity building will further NIDDK STEP-UP’s reach into the Pacific communities by bringing awareness of the interdependency of the well beings of humans, animals, and the eco-environment; and its impact on health-related issues. The goal is to seed and shape a culture that values One Health research as the means to address pertinent health issues in these communities, and grow a cadre of “home-grown” scientists readied to research for solutions. In doing so, we will fulfill NIDDK’s STEP-UP mission to build and diversify a pipeline of future scientists interested in tackling health and disease questions related to NIDDK from multiple angles of trans-sectorial and trans- disciplinary approach under One Health. Accordingly, we propose three Specific Aims. (1). Recruit best qualified high school students (11th and 12th grade) from the seven US State and Territories in the Pacific into the STEP-UP Summer Research Program, and track the cohort’s academic progress for a minimum of 5 years. (2). Provide individualized research experience (and related education and training) that stresses One Health approach, and local community or population relevance. Provide STEP-UP alumni with follow up, and research-focused, mentoring extending for 9 months. (3). Seed and nurture interests in One Health in high school students while strengthening local colleges’ capacity to enable laboratory-, field-, and community-based research with a focus on One Health concepts, all in support of the Pacific STEP-UP program by expanding application pool and research opportunities, and strengthening the research training program.