MOLECULAR AND CELLULAR IMMUNOLOGY CORE

分子和细胞免疫学核心

• 批准号: 8360752
• 负责人: George S Hui
• 金额: $ 31.37万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360752
• 关键词: Biological Assay; Cell Separation; Cellular Immunology; Centers of Research Excellence; Communities; Development; Educational workshop; Emerging Communicable Diseases; Equipment; Extramural Activities; Faculty; Flow Cytometry; Funding; Grant; Health Services Research; Immune; Infectious Diseases Research; Mentors; Methods; Mission; Molecular Immunology; National Center for Research Resources; Principal Investigator; Productivity; Publications; Research; Research Infrastructure; Research Personnel; Resources; Schedule; Services; Source; Students; Techniques; Training; Training and Education; United States National Institutes of Health; Universities; base; cost; experience; improved; meetings; novel; research and development

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. By building on an equipment grant to purchase a research-dedicated FACSCalibur flow cytometer in 2001, COBRE funds were leveraged to develop core services in flow cytometry and other immune-based assays, as part of the overall Technical Support Core during the initial COBRE grant period. High demand for all support services have prompted the proposed development of a stand-alone core for molecular and cellular immunology. The new grant period will witness the maturation of this core to meet the mission of service, research and development, and education and training. As the sole resource for flow cytometry, cell sorting and state-of-the-art immunological services in the westernmost IDeA state, the Molecular and Cellular Immunology Core will accelerate research productivity, in terms of publications and extramural funding. Emphasis will also be applied to developing new or customized immunological methods for COBRE Investigators and other Core users. In addition, regularly scheduled training sessions will be held to enrich the educational and mentoring experience for COBRE Investigators and other faculty and students across the University and broader research community. It is envisioned that by centralizing immunological services and resources to this Core, COBRE Investigators and other researchers will be more efficiently served and the use of expensive equipment will be maximized. Specific Aim 1. Enhance support and services in molecular and cellular immunology. Specific Aim 2. Develop improved immunological assays and explore novel applications for existing techniques. Specific Aim 3. Develop and implement training and education workshops in molecular and cellular immunology.

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 通过2001年购买专门用于研究的FACSCalibur流式细胞仪的设备赠款，Cobre资金被用来开发流式细胞仪和其他基于免疫的分析的核心服务，作为最初Cobre赠款期间整体技术支持核心的一部分。对所有支持服务的高需求促使提议开发一个独立的分子和细胞免疫学核心。新的授权期将见证这一核心的成熟，以满足服务、研究和开发以及教育和培训的使命。分子和细胞免疫学核心作为在最西方的理想状态下提供流式细胞术、细胞分类和最先进的免疫学服务的唯一资源，将在出版物和外部资金方面加快研究生产率。还将把重点放在为Cobre研究人员和其他核心用户开发新的或定制的免疫方法上。此外，还将定期举办培训课程，以丰富Cobre研究人员以及大学和更广泛的研究社区的其他教职员工和学生的教育和指导经验。据设想，通过将免疫服务和资源集中到这一核心，Cobre研究人员和其他研究人员将得到更有效的服务，并将最大限度地使用昂贵的设备。 具体目标1.加强分子和细胞免疫学方面的支持和服务。 具体目标2.开发改进的免疫学分析方法，探索现有技术的新应用。 具体目标3.开发和实施分子和细胞免疫学培训和教育讲习班。