Developing Diverse Physician-Investigator Leaders for the Future of Child Health

摘要 早期儿科教师，即使是那些有潜力成为学术研究者的人 基于在基础研究方面的丰富经验，将需要在基础研究方面进行进一步的强化培训和指导。 研究，以成功地走上独立的研究生涯。儿童健康研究 职业发展奖（CHRCDA）计划，题为“发展多样化的医生-研究者领导者 “儿童健康的未来”将提供一个前沿的研究机会，结合精心设计的 建立了指导和职业发展途径，使我们的学者成为领导者， 儿科学术研究者的行列。大学的基础生物医学研究培训社区 加州圣地亚哥分校（UCSD）拥有悠久的卓越声誉，UCSD儿科现在排名 在全国所有儿科的NIH研究经费中排名前五。值得注意的是，过去5-10年 已经目睹了令人印象深刻的学术扩张内的儿科和加州大学圣地亚哥分校 它进行的研究，加上与圣地亚哥拉迪儿童医院的正式合作， 加州最大的儿童医院我们的CHRCDA的主要目标如下：（1）增加 从事儿童健康基础研究的儿科医生-科学家人数;（2）吸引 优秀的年轻儿科医生到UCSD，并促进他们的职业发展的指导下，世界 类，建立了教师导师;（3）培养妇女和少数民族的早期职业生涯 儿童健康调查员。随着我们部门的计划先驱的密切投入，CHRCDA 学者将充分参与UCSD国家学术医学领导中心的计划 （NCLAM），一个长期和非常成功的初级教师辅导计划在加州大学健康科学， 提供研讨会和纵向辅导，在学术成功发展所需的各个方面 医学和多样性丰富模块，包括边境健康和医生的一天方案。所有 CHRCDA计划教师导师都是备受推崇的科学研究者，每个人都领导着一个充满活力和 与儿科医学密切相关的尖端基础或基础/转化研究计划。研究 CHRCDA学者的培训机会分为六个研究主题，每个主题五名成员， 在程序结构，课程和指导方法中发挥不可或缺的作用：（1）基因组学，大数据和 系统生物学;（2）感染、免疫和炎症;（3）器官生理学和代谢;（4）神经科学 和大脑发育;（5）人类微生物组和儿童健康;和（6）发育和干细胞生物学。一 CHRCDA的指导思想是支持尽可能多的年轻医生-科学家 在该计划中，在K12的三年中增加了一年的部门资助支持 支持创建一个充满活力的计划，每年有一名新学者和四名研究员处于稳定状态。

ABSTRACT Early stage pediatric faculty members, even those who have potential for success as academic investigators based upon substantial experience in basic research, will require further intensive training and mentoring in basic research to successfully embark upon an independent research career. Our proposed Child Health Research Career Development Award (CHRCDA) Program entitled “Developing Diverse Physician-Investigator Leaders for the Future of Child Health” will provide a cutting-edge research opportunities, combined with a carefully constructed mentoring and career development pathway, to enable our Scholars to emerge as leaders among the ranks of pediatric academic investigators. The basic biomedical research training community at the University of California San Diego (UCSD) has a long-established reputation of excellence, and UCSD Pediatrics now ranks in the top five in NIH research funding of all Pediatric Departments in the country. Notably, the last 5-10 years have witnessed an impressive academic expansion within of the UCSD Department of Pediatrics and the research it conducts, coupled with the formalization of its partnership with Rady Children's Hospital San Diego, the largest Children's Hospital in California. The key objectives of our CHRCDA are as follows: (1) To increase the number Pediatrician-Scientists engaged in basic research as applied to children's health; (2) to attract outstanding young pediatricians to UCSD and to facilitate their career development under the guidance of world class, established investigator-faculty mentors; and (3) to cultivate the early careers of women and minority investigators in children's health. With close input from the program pioneers in our Department, CHRCDA Scholars will participate fully in the program of UCSD National Center for Leadership in Academic Medicine (NCLAM), a longstanding and highly successful junior faculty mentoring program in UC Health Sciences that provides workshops and longitudinal mentoring in all facets required for successful advancement in academic medicine, and diversity enrichment modules including the Border Health and Doc-for-A-Day programs. All CHRCDA program faculty mentors are highly regarded scientific investigators, each leading a vibrant and cutting-edge basic or basic/translational research program of strong relevance to pediatric medicine. Research training opportunities for CHRCDA Scholars are organized into six research themes of five members each, which an integral role in the program structure, curriculum and mentorship approach: (1) Genomics, Big Data & Systems Biology; (2) Infection, Immunity & Inflammation; (3) Organ Physiology & Metabolism; (4) Neuroscience & Brain Development; (5) Human Microbiome & Child Health; and (6) Developmental & Stem Cell Biology. A guiding philosophy of this CHRCDA will be to support the greatest possible number of young physician-scientists within this Program, and an additional year of Department-funded support has been added to three years of K12 support to create a vibrant program with one new Scholar per year and four fellows total in the steady state.