Administrative Core

行政核心

• 批准号: 10406866
• 负责人: Mary Sano
• 金额: $ 62.96万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10406866
• 关键词: Accountability; Address; Administrator; Advisory Committees; Alzheimer disease prevention; Alzheimer' s Disease; Animals; Applied Research; Budgets; Calendar; Clinical; Collaborations; Communication; Communities; Data; Data Collection; Dementia; Detection; Development; Diagnosis; Diagnostic; Disease; Education; Ensure; Evaluation; Event; Faculty; Faculty Recruitment; Fostering; Funding; Funding Agency; Goals; Health Insurance Portability and Accountability Act; Health system; Heterogeneity; Infrastructure; Institution; International; Knowledge; Leadership; Location; Mentors; Mission; Monitor; Performance; Process; Productivity; Regulation; Research; Research Personnel; Resources; Sampling; Science; Structure; Technology; Therapeutic; Time; Translational Research; cell repository; cohort; comorbidity; disease heterogeneity; education research; human subject; improved; knowledge of results; medical schools; meetings; outreach; programs; recruit; resilience; resource guides; sample collection; success

Mount Sinai ADRC (Sano): Administrative Core (Core A) – Research Summary The Administrative Core of the MSADRC provides leadership to manage and coordinate the research agenda for the MSADRC to ensure success in our mission to “Understand disease heterogeneity to optimize therapeutic approaches to treat and cure Alzheimer's disease”. The overall aims are as follows. 1) To provide leadership and an operational infrastructure to facilitate communication among cores, and with national entities including NIA program staff, National Alzheimer's Disease Coordinating Center (NACC) and the National Cell Repository for Alzheimer's Disease (NCRAD). The structure includes an Executive Committee (EC) an External Advisory Committee (EAC), and an Internal Advisory Committee. The Core also maintains administrative, financial and regulatory oversight. 2) To ensure that the MSADRC addresses the agenda of the National Alzheimer's Project Act (NAPA). 3) To create a program that supports developmental projects that will stimulate Alzheimer's disease (AD) research around the institution. 4) To evaluate all activities to ensure they generate the planned resources and disseminate them broadly, and to optimize their impact on finding a cure for AD. The Administrative Core oversees activities across two locations, the Icahn School of Medicine at Mount Sinai (ISMMS) and the James J Peters VAMC. Through a clear structure for governance, with a set of advisory and working committees, and a calendar of meetings with prescribed agendas, the Administrative Core assures coordinated interaction among the Directors and the Core Leaders. The Administrative Core assures that the recruitment and retention of a diverse cohort, the data and sample collection, and data distribution all occur in a timely manner. It assists the Research Education Component in its task to identify AD Scholars successfully, enrich their education through mentoring from all of the MSADRC Core Leaders and enhance their research opportunities using resources provided by the Cores. This is achieved through regular meetings with all Core staff to address operational issues and to foster collaboration across MSADRC faculty, and with other AD researchers within ISMMS and beyond. The Administrative Core guarantees that data and samples are provided to NACC and NCRAD in a timely manner; it is responsible for communicating with the funding agency, the NIA Center program leaders and staff, to promote dissemination of research findings and opportunities to the widest community. The Core administrator oversees fiscal and regulatory issues, guaranteeing compliance with guidance for human subject and animal protection, organizes the annual call for Developmental Projects including preparing and disseminating a call for proposals and organizing a scientific review under the leadership of the MSADRC Director and Associate Directors. The administrator also assists with tracking evaluations of core performance, REC success, productivity of Developmental Projects, and faculty recruitment and promotion. !

西奈山ADRC（佐野）：行政核心（核心A）-研究摘要 MSADRC的行政核心提供领导，以管理和协调研究议程 为MSADRC确保成功完成我们的使命，“了解疾病异质性， 治疗和治愈阿尔茨海默病的治疗方法”。总体目标如下。1)提供 领导和业务基础设施，以促进核心之间以及与国家实体的沟通 包括NIA项目工作人员、国家阿尔茨海默病协调中心（NACC）和国家细胞 阿尔茨海默病知识库（NCRAD）。该结构包括一个执行委员会（EC）， 外部咨询委员会（EAC）和内部咨询委员会。核心还认为， 行政、财务和管理监督。2)确保MSADRC处理大会议程， 国家阿尔茨海默病项目法案（NAPA）。3)创建一个支持发展项目的计划， 将刺激该机构周围的阿尔茨海默病（AD）研究。4)评估所有活动，以确保 它们产生计划的资源并广泛传播，并优化其对寻找 治愈AD行政核心监督两个地点的活动，伊坎医学院， 西奈山（ISMMS）和詹姆斯J彼得斯VAMC。通过一个明确的治理结构， 咨询委员会和工作委员会，以及附有规定议程的会议日历，行政 核心确保董事和核心领导人之间的协调互动。行政核心 确保招募和保留多样化的队列，收集数据和样本， 分配都是及时进行的。它协助研究教育部分的任务，以确定广告 学者成功，丰富他们的教育，通过指导所有的MSADRC核心领导人， 利用核心提供的资源增加他们的研究机会。这是通过定期 与所有核心工作人员的会议，以解决业务问题，并促进整个MSADRC教师的合作， 以及ISMMS内外的其他AD研究人员。行政核心保证数据和 及时向NACC和NCRAD提供样品;负责与 资助机构，NIA中心项目负责人和工作人员，以促进研究成果的传播， 为最广泛的社区提供机会。核心管理员负责监督财政和监管问题， 确保遵守人类受试者和动物保护指南，组织年度呼吁， 发展项目，包括编写和散发提案呼吁，并组织一次科学 在MSADRC主任和副主任的领导下进行审查。管理员还协助 跟踪评估核心绩效、REC成功率、发展项目的生产力， 教师招聘和晋升。 !