Health Systems Core
Health Systems Core
批准号:
10229433
负责人:
Eric B Larson
金额:
$57.44万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-01 至 2024-06-30
关键词:
Academic Medical CentersAddressAdoptedAdoptionAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaCaregiversCaringCommunitiesComplexDataDementiaDementia caregiversDevelopmentDiagnosisEffectiveness of InterventionsElectronic Health RecordEmotionalEnsureFinancial HardshipFosteringFoundationsFundingHealth systemHealthcareHealthcare SystemsHeterogeneityHospitalsInstitutionIntegrated Delivery SystemsInterventionK-Series Research Career ProgramsKnowledgeLeadLearningMedicalNational Institute on AgingNursing HomesPatientsPersonsPilot ProjectsPopulationPragmatic clinical trialProviderReadinessResearchResearch PersonnelResourcesService delivery modelStandardizationSystemTestingUnited States National Institutes of HealthWorkWorld Healthbasecase findingclinical practicecollaboratorydata exchangedesignefficacious interventionexperiencefeasibility testinghealth care deliveryhealth care service organizationimprovedinformal caregiverinsightknowledge basemeetingsnovelpatient home careprogramsresearch studysuccessful interventionsystems researchtherapy designvirtual
中文摘要
项目总结
大多数痴呆症患者(PWD)在机构外接受护理,这意味着身体,情感,
痴呆症的经济负担不仅由患者承担,而且由他们的照顾者承担。支离破碎的,
复杂的美国医疗体系加剧了提供协调的、全方位的医疗服务的挑战
PWD。设计和测试有效、可行的非药物干预措施必须考虑到
医疗保健格局的异质性、这一复杂人群的特定需求以及背景
在这里提供护理服务。尽管旨在改善对PWD和他们的护理的多种干预措施
护理者已经证明了有效性,很少有人被广泛采用,几乎没有人在
正常运作的卫生保健系统(HCS)。反映了在优化护理中存在的许多悬而未决的问题
PWD,我们的当务之急是缩小干预措施的开发和测试与其后期之间的差距
在真实的HCS中采用。因此,要发展强大的国家能力来支持嵌入式实用
临床试验(EPCT),我们必须利用研究人员和一线临床医生的组合专业知识来
设计干预措施,确保可复制性、可扩展性和可持续性。我们将把这些专业知识应用于我们
解决实施ePCT的独特错综复杂的问题,重点满足残疾人及其
照顾者。拟议中的国家老龄研究所(NIA)的医疗保健系统(HCS)核心
阿尔茨海默病(AD)/AD相关痴呆(AD/ADRD)HCS合作实验室将聘请来自
综合交付系统、学术医疗中心、疗养院系统、家庭护理公司和
其他以社区为基础的提供者以实现以下具体目标。目标1.建立一个协作的、
涉及不同初级保健机构的支持性研究资源,以支持和促进环境中的研究
残疾人及其照顾者接受护理的地方;目标2.制定、记录和传播特定环境
在残疾人中开展ePCT的方法;目标3.促进开展严格的试点研究、职业生涯
发展奖(CDA)项目,以及美国国立卫生研究院资助的各种护理中心的ePCT,目标是残障人士及其
照顾者。影响:成功的HCS核心将与其他AD/ADRD合作实验室核心合作,并
促进以残障人士及其照顾者为重点的严谨、高质量的研究
多个医疗保健提供机构参与其中。结合ePCT方面的深厚专业知识和第一手
在一系列环境中照顾AD/ADRD人群的知识,HCS核心将成为
无与伦比的国家研究资源,帮助发布成功的基于HCS的干预措施,旨在
满足残疾人、照顾者和为他们服务的卫生系统的需求。
英文摘要
PROJECT SUMMARY
Most persons with dementia (PWD) receive care outside of institutions, meaning that the physical, emotional,
and financial burdens of dementia are borne not only by patients, but their caregivers as well. The fragmented,
complex US health care system exacerbates the challenge of delivering coordinated, whole-person care for
PWD. Designing and testing effective, practicable, non-pharmacological interventions must take into account
the heterogeneity of the health care landscape, the specific needs of this complex population, and the context
in which care is delivered. Although multiple interventions designed to improve care for PWD and their
caregivers have demonstrated efficacy, few have been adopted widely, and virtually none formally tested in
functioning health care systems (HCS). Reflecting the many unanswered questions in optimizing care for
PWD, our imperative is to close the gap between the development and testing of interventions and their later
adoption in real-world HCS. Thus, to develop a robust national capability to support embedded pragmatic
clinical trials (ePCT), we must leverage the combined expertise of researchers and front-line clinicians to
design interventions that ensure replicability, scalability, and sustainability. We will apply this expertise as we
address the unique intricacies of conducting ePCTs focused on meeting the needs of PWD and their
caregivers. The Health Care Systems (HCS) Core of the proposed National Institute on Aging (NIA)
Alzheimer's disease (AD)/AD-related dementia (AD/ADRD) HCS Collaboratory will engage experts from
integrated delivery systems, academic medical centers, nursing home systems, home care companies and
other community based providers to accomplish the following Specific Aims. Aim 1. Establish a collaborative,
supportive research resource involving diverse HCS in order to support and facilitate research in the settings
where PWD and their caregivers receive care; Aim 2. Develop, document, and disseminate setting-specific
approaches to conducting ePCTs in PWD; Aim 3. Facilitate the conduct of rigorous pilot studies, Career
Development Award (CDA) projects, and NIH-funded ePCTs in diverse care HCS targeting PWD and their
caregivers. IMPACT: A successful HCS Core will partner with the other AD/ADRD Collaboratory Cores and
Teams to facilitate rigorous, high-quality research studies focused on PWD and their caregivers, in which
multiple health care delivery organizations participate. Combining deep expertise in ePCTs and first-hand
knowledge of caring for the AD/ADRD population in a range of settings, the HCS Core will become an
unparalleled national research resource to help promulgate successful HCS based interventions designed to
meet the needs of PWD, caregivers, and health systems that serve them.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Annual Adult Changes in Thought (ACT) symposium on aging, dementia, and Alzheimer's disease
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批准号:10066181
-
项目类别:
-
资助金额:$5.0万
-
财政年份:2020
-
负责人:Eric B Larson
-
依托单位:
Health Systems Core
-
批准号:10673678
-
项目类别:
-
资助金额:$80.41万
-
财政年份:2019
-
负责人:Eric B Larson
-
依托单位:
Health Systems Core
-
批准号:10443678
-
项目类别:
-
资助金额:$79.36万
-
财政年份:2019
-
负责人:Eric B Larson
-
依托单位:
Multidomain Alzheimers Risk Reduction Study (MARRS) Pilot
-
批准号:9697410
-
项目类别:
-
资助金额:$125.84万
-
财政年份:2017
-
负责人:Eric B Larson
-
依托单位:
Multidomain Alzheimers Risk Reduction Study (MARRS) Pilot
-
批准号:9422490
-
项目类别:
-
资助金额:$137.11万
-
财政年份:2017
-
负责人:Eric B Larson
-
依托单位:
The ACT annual symposium: a living, learning, national collaboratory to advance Alzheimer's disease and brain aging research
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批准号:9395822
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项目类别:
-
资助金额:$4.95万
-
财政年份:2017
-
负责人:Eric B Larson
-
依托单位:
Development and Use of Network Infrastructure for High-Throughput GWA Studies
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批准号:7902293
-
项目类别:
-
资助金额:$88.92万
-
财政年份:2007
-
负责人:Eric B Larson
-
依托单位:
Development and Use of Network Infrastructure for High-Throughput GWA Studies
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批准号:7688756
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项目类别:
-
资助金额:$21.93万
-
财政年份:2007
-
负责人:Eric B Larson
-
依托单位:
Development and Use of Network Infrastructure for High-Throughput GWA Studies
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批准号:7921317
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项目类别:
-
资助金额:$11.85万
-
财政年份:2007
-
负责人:Eric B Larson
-
依托单位:
Development and Use of Network Infrastructure for High-Throughput GWA Studies
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批准号:7427364
-
项目类别:
-
资助金额:$97.06万
-
财政年份:2007
-
负责人:Eric B Larson
-
依托单位:
Development and Use of Network Infrastructure for High-Throughput GWA Studies
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批准号:7684273
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项目类别:
-
资助金额:$103.97万
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财政年份:2007
-
负责人:Eric B Larson
-
依托单位:
Development and Use of Network Infrastructure for High-Throughput GWA Studies
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批准号:7502172
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项目类别:
-
资助金额:$98.75万
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财政年份:2007
-
负责人:Eric B Larson
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依托单位:
Re-Engineering the Clinical Research Enterprise
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批准号:7058405
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项目类别:
-
资助金额:$0.0万
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财政年份:2004
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
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批准号:6168089
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项目类别:
-
资助金额:$103.47万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
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批准号:2413318
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项目类别:
-
资助金额:$95.95万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
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批准号:2051046
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项目类别:
-
资助金额:$95.82万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA
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批准号:2051043
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项目类别:
-
资助金额:$79.39万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
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批准号:3121670
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项目类别:
-
资助金额:$4.02万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
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批准号:3121671
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项目类别:
-
资助金额:$13.79万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
EPIDEMIOLOGY OF DEMENTIA IN OLDER JAPANESE AMERICANS
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批准号:3121669
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项目类别:
-
资助金额:$57.59万
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财政年份:1991
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负责人:Eric B Larson
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依托单位:
海外基金