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Alternate Emergency Over Dose Response in Chicago

芝加哥的替代紧急剂量反应

基本信息

批准号：
10425012
负责人：
HAROLD Alexander POLLACK
金额：
$ 20.5万
依托单位：
UNIVERSITY OF CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-05-15 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10425012
关键词：
911 call Address Algorithms Ambulances Area Assertiveness Authorization documentation Buprenorphine Case Management Catchment Area Characteristics Chicago Cities Clinical Data Collaborations Communication Communities Consolidated Framework for Implementation Research County Data Data Set Dose Effectiveness Emergency Situation Emergency medical service Emergency response Fire - disasters Funding Future Grant Health Health Professional Health Service Area Individual Injecting drug user Intervention Interview Journals Machine Learning Medical Examiners Medical emergency Modeling Neighborhoods Opioid Outcome Overdose Paramedical Personnel Participant Performance Persons Pharmaceutical Preparations Police Policies Population Predictive Analytics Prevalence Probability Program Effectiveness Public Health Publications Randomized Recovery Research Research Design Resources Risk Risk Factors Safety Services Side Signal Transduction Source Specialist System Technology Transfer Text University resources adverse outcome austin base behavioral health brief intervention care coordination community based care computer code cooking design experience follow-up high risk hybrid type 1 study implementation barriers implementation facilitators improved innovation insight longitudinal analysis member mortality open source operation opioid overdose opioid use disorder outreach outreach services overdose risk patient engagement peer peer support post intervention prescription opioid process evaluation programs random forest response service delivery service engagement service intervention sociodemographics tool treatment arm unstructured data

项目摘要

PROJECT ABSTRACT Chicago is a national epicenter of opioid overdose (OD) and related harms. Opioid-related Emergency Service Calls (ORESCs) are critical opportunities for service engagement and intervention. Nationally and in Chicago, high mortality rates subsequent to non-fatal OD underscore that such opportunities are often missed. Chicago will pilot two innovative responses to address these challenges. Alternate Immediate Response (AIR) will provide assertive outreach and engagement, including connecting people with medication opioid use disorder treatment and other related services. Alternate Immediate Response plus Follow-up (AIR-F) includes AIR, along with 8 weeks of follow-up services. AIR response teams consisting of a community paramedic and a peer support specialist/recovery coach will be deployed to provide assertive outreach services, including developing treatment, safety, and follow-up plans, delivering brief interventions, and providing transport to pertinent other services. AIR-F engagement will include linkages to follow-up services that promote treatment retention, including case management, care coordination, and connections to community-based care and treatment. We propose to use machine learning (ML) to develop a tool to identify individuals at highest risk of OD and OD-related mortality in order to prioritize service delivery and follow-up services. In particular, we will develop a random forest (RF) classifier that will combine data from the Chicago Department of Public Health, the Office of Emergency Management and Communications, Chicago Police and Fire departments, Chicago Office of Public Safety Administration, and Cook County Medical Examiner’s Office to create an integrated dataset to trace emergency calls from origination to final disposition. We will also extract data from unstructured text included in CFD ambulance data. By incorporating multiple large administrative datasets, the tool will capitalize on diverse sources of “signal,” maximizing prediction accuracy. We will then use our integrated data to predict individuals at highest risk of subsequent ORESCs, OD, arrest, and other adverse outcomes. AIR/AIR-F staff will use these indicators along with other clinical data to allocate scarce follow-up resources. We will use difference-in-differences estimation to compare post-intervention outcomes within the service area on Chicago’s west side (Humboldt Park, West Garfield Park, and East Garfield Park) to that observed in contiguous communities (Austin, North Lawndale, South Lawndale, Lower West Side, and West Town) to gauge the population impact of AIR/AIR-F. Finally, we will conduct qualitative interviews with various stakeholders to provide additional insight into the pilot and explore how Chicago can better serve at-risk individuals. To help reduce the prevalence of ORESCs’ and associated mortality, all computer code developed for this grant will be made available open-source. We will disseminate project findings widely throughout the policy and scientific communities, including publication in leading scientific journals and policymaker and media outreach.

项目摘要