Core A: Administrative Core

核心A：行政核心

• 批准号: 10640137
• 负责人: MARY CUSHMAN
• 金额: $ 80.93万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-06 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10640137
• 关键词: Accountability; Advisory Committees; American; Annual Reports; Attention; Award; Basic Science; Brain Diseases; Budgets; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Centers of Research Excellence; Clinical; Clinical Investigator; Clinical Sciences; Collaborations; Communication; Communities; Core Facility; Data; Databases; Dementia; Development; Dimensions; Discipline; Disease; Education; Ensure; Equity; Faculty; Fostering; Foundations; Funding; Future; General Population; Goals; Grant; Health; Heart; Image; Impaired cognition; Infrastructure; Institution; Leadership; Medicine; Mentors; Mentorship; Microvascular Dysfunction; Molecular Epidemiology; Outcome; Pathogenesis; Persons; Phase; Physiology; Positioning Attribute; Program Development; Protocols documentation; Research; Research Design; Research Institute; Research Personnel; Resources; Science; Scientist; Services; Specimen; Strategic Planning; Stroke; Teacher Professional Development; Techniques; Underrepresented Minority; Universities; Vermont; Woman; Work; brain health; cardiovascular health; career; career development; cohort; college; cost; disability; experience; faculty mentor; improved; innovation; interest; man; member; multidisciplinary; neurovascular; next generation; operation; peer coaching; programs; prospective; recruit; research and development; success; symposium

Cardiovascular disease, stroke and cognitive impairment / dementia are leading causes of death and disability, and they arise from several common antecedents. The Vermont Center for Cardiovascular and Brain Health (VCCBH) COBRE at the University of Vermont (UVM) will address these diseases by supporting diverse scientists from multiple disciplines who will work together to understand the pathobiology and molecular epidemiology of these diseases. The Administrative Core (Core A), led by COBRE PIs Drs. Mary Cushman and Mark Nelson, will be the heart of the VCCBH. It will provide administrative infrastructure and resources that will produce the next generation of science leaders at UVM. Four junior faculty Project Directors (PDs) are central to our effort. Core A will be accountable for key functions necessary for PD success, for Cores, for engaging prospective PDs to replace the first cohort, and ultimately, for the future sustainability of the VCCBH. Core A will foster innovation by creating a culture of openness, diversity, and collaboration. The Core will administer an Interdisciplinary Strategic Mentoring Initiative to guide PDs to independent status (Aim 1). Multidisciplinary mentoring teams will include two Senior Mentors, a Peer Mentor at the “first independent step” career stage, and an experienced External Mentor. The Peer Mentor will benefit from this early opportunity to provide faculty mentoring. The Core will develop and employ a comprehensive Faculty Development Program (FDP) and Core facilities focused on PDs (Aim 2). The FDP will be highlighted by an institutionally supported Pilot Grant Award program that will provide 4 grants of $200,000 each to pairs of junior faculty with different research backgrounds. The capstone of the FDP will be an annual 2-day research symposium that will highlight PD research and development of new projects. The Core will supervise development of new Cores in “Study Design and Molecular Epidemiology” and “Customized Physiology and Imaging.” The Core will manage the VCCBH budget, and assist and educate the PDs in budget management (Aim 3). Core A will coordinate Internal and External Advisory Boards, develop outcome metrics, and provide semi-annual reports on these to PDs, mentor teams, and Advisory Boards (Aim 4). Finally, the Core will provide communication across the University and beyond on the Center's scientific expertise, Core resources and databases, and resources generated by the VCCBH (data, specimens, study protocols, new techniques, and research results) (Aim 5). A Communications Committee will include professionals from the Office of Communications of the Larner College of Medicine and the UVM Foundation in order to promote philanthropy. By completing the Specific Aims we will: (1) propel 4 early-career scientists to independence; (2) cultivate a pipeline of early career scientists to fill PD positions as original PDs achieve funding; (3) recruit 5 new junior faculty to UVM to enter our pipeline of prospective PDs; (4) promote collaboration amongst faculty and trainees working in cardiovascular and neurovascular research across the colleges of UVM.

心血管疾病、中风和认知障碍/痴呆是导致死亡和残疾的主要原因， 它们源于几个共同的先例。佛蒙特州心血管和大脑健康中心 (VCCBH)佛蒙特州大学(UVM)的科布雷将通过支持各种 来自多个学科的科学家将共同努力，了解病原体和分子 这些疾病的流行病学。行政核心(核心A)，由科布雷私人助理玛丽·库什曼博士领导 以及马克·纳尔逊，将成为VCCBH的核心。它将提供行政基础设施和资源 这将为密歇根大学培养下一代科学领袖。四名初级教员项目主任(PD)是 是我们努力的核心。核心A将负责PD成功所必需的关键功能、核心、 吸引未来的PD来取代第一批人，并最终实现VCCBH未来的可持续性。 核心A将通过创造开放、多样化和协作的文化来促进创新。核心意志 管理跨学科战略指导倡议，以指导私营部门走向独立地位(目标1)。 多学科指导团队将包括两名高级导师，一名处于“第一个独立步骤”的同行导师 职业生涯阶段，并有经验丰富的外部导师。同行导师将从这一早期机会中受益 提供教职员工指导。核心学院将开发和使用一个全面的教师发展计划 (FDP)和以私营部门为重点的核心设施(目标2)。自民党将由一个机构支持的 试点助学金计划将向具有不同技能的初级教员对提供4笔助学金，每笔200,000美元 研究背景。自民党的顶峰是一年一度的为期两天的研究研讨会，将 突出PD新项目研发。该核心将监督#年新核心的开发。 《研究设计与分子流行病学》和《定制生理学与成像》。核心将管理 VCCBH预算，并在预算管理方面协助和教育PDS(目标3)。核心A将协调 内部和外部咨询委员会，制定成果指标，并就这些指标提供半年度报告 PDS、导师团队和咨询委员会(目标4)。最后，核心将提供跨 关于该中心的科学专业知识、核心资源和数据库以及资源 由VCCBH生成(数据、样本、研究方案、新技术和研究结果)(目标5)。一个 通信委员会将包括来自通信办公室的专业人员 医学学院和密歇根州立大学基金会，以促进慈善事业。通过完成特定的 我们的目标是：(1)推动4名早期职业科学家走向独立；(2)培养早期职业管道 科学家填补PD职位，作为原始PD实现资助；(3)招聘5名新的初级教员到UVM进入 我们未来的个人发展计划；(4)促进教职员和受训人员之间的合作 UVM各学院的心血管和神经血管研究。