Core A: Administrative Core

核心A：行政核心

• 批准号: 10885876
• 负责人: MARY CUSHMAN
• 金额: $ 66.05万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-06 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10885876
• 关键词: Accountability; Advisory Committees; American; Annual Reports; Attention; Award; Basic Science; Brain Diseases; Budgets; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Centers of Research Excellence; Clinical; Clinical Investigator; Clinical Sciences; Collaborations; Communication; Communities; Core Facility; Data; Databases; Dementia; Development; Dimensions; Discipline; Disease; Education; Ensure; Equity; Faculty; Fostering; Foundations; Funding; Future; General Population; Goals; Grant; Health; Heart; Image; Impaired cognition; Infrastructure; Institution; Leadership; Medicine; Mentors; Mentorship; Microvascular Dysfunction; Molecular Epidemiology; Outcome; Pathogenesis; Persons; Phase; Physiology; Positioning Attribute; Program Development; Protocols documentation; Research; Research Design; Research Institute; Research Personnel; Resources; Science; Scientist; Services; Specimen; Strategic Planning; Stroke; Teacher Professional Development; Techniques; Underrepresented Minority; Universities; Vermont; Woman; Work; brain health; cardiovascular health; career; career development; cohort; college; cost; disability; experience; faculty mentor; improved; innovation; interest; man; member; multidisciplinary; neurovascular; next generation; operation; peer coaching; programs; prospective; recruit; research and development; success; symposium

Cardiovascular disease, stroke and cognitive impairment / dementia are leading causes of death and disability, and they arise from several common antecedents. The Vermont Center for Cardiovascular and Brain Health (VCCBH) COBRE at the University of Vermont (UVM) will address these diseases by supporting diverse scientists from multiple disciplines who will work together to understand the pathobiology and molecular epidemiology of these diseases. The Administrative Core (Core A), led by COBRE PIs Drs. Mary Cushman and Mark Nelson, will be the heart of the VCCBH. It will provide administrative infrastructure and resources that will produce the next generation of science leaders at UVM. Four junior faculty Project Directors (PDs) are central to our effort. Core A will be accountable for key functions necessary for PD success, for Cores, for engaging prospective PDs to replace the first cohort, and ultimately, for the future sustainability of the VCCBH. Core A will foster innovation by creating a culture of openness, diversity, and collaboration. The Core will administer an Interdisciplinary Strategic Mentoring Initiative to guide PDs to independent status (Aim 1). Multidisciplinary mentoring teams will include two Senior Mentors, a Peer Mentor at the “first independent step” career stage, and an experienced External Mentor. The Peer Mentor will benefit from this early opportunity to provide faculty mentoring. The Core will develop and employ a comprehensive Faculty Development Program (FDP) and Core facilities focused on PDs (Aim 2). The FDP will be highlighted by an institutionally supported Pilot Grant Award program that will provide 4 grants of $200,000 each to pairs of junior faculty with different research backgrounds. The capstone of the FDP will be an annual 2-day research symposium that will highlight PD research and development of new projects. The Core will supervise development of new Cores in “Study Design and Molecular Epidemiology” and “Customized Physiology and Imaging.” The Core will manage the VCCBH budget, and assist and educate the PDs in budget management (Aim 3). Core A will coordinate Internal and External Advisory Boards, develop outcome metrics, and provide semi-annual reports on these to PDs, mentor teams, and Advisory Boards (Aim 4). Finally, the Core will provide communication across the University and beyond on the Center's scientific expertise, Core resources and databases, and resources generated by the VCCBH (data, specimens, study protocols, new techniques, and research results) (Aim 5). A Communications Committee will include professionals from the Office of Communications of the Larner College of Medicine and the UVM Foundation in order to promote philanthropy. By completing the Specific Aims we will: (1) propel 4 early-career scientists to independence; (2) cultivate a pipeline of early career scientists to fill PD positions as original PDs achieve funding; (3) recruit 5 new junior faculty to UVM to enter our pipeline of prospective PDs; (4) promote collaboration amongst faculty and trainees working in cardiovascular and neurovascular research across the colleges of UVM.

心血管疾病、中风和认知障碍/痴呆是死亡和残疾的主要原因， 它们有几个共同的起源。佛蒙特州心血管和大脑健康中心 （VCCBH）佛蒙特大学（UVM）的COBRE将通过支持各种 来自多个学科的科学家将共同努力，了解病理生物学和分子生物学， 这些疾病的流行病学。行政核心（核心A），由COBRE PI玛丽库什曼博士领导 和马克纳尔逊，将是VCCBH的核心。它将提供行政基础设施和资源 将在弗吉尼亚大学培养下一代科学领袖。四名初级教员项目主任（PD）是 我们努力的核心。核心A将负责PD成功所需的关键职能， 让预期的PD取代第一批，并最终实现VCCBH的未来可持续性。 核心A将通过创造开放、多样和协作的文化来促进创新。芯会 管理跨学科战略指导计划，引导PD获得独立地位（目标1）。 多学科指导小组将包括两名高级指导员，一名“第一个独立步骤”的同伴指导员 职业生涯阶段，以及经验丰富的外部导师。同行导师将受益于这个早期的机会， 提供教师指导。核心将制定和采用全面的教师发展计划 (FDP)核心设施专注于PD（目标2）。FDP将由一个机构支持的 试点赠款奖计划，将提供4个赠款$200，000对初级教师与不同的 研究背景。FDP的顶峰将是一年一度的为期两天的研究研讨会， 突出PD研发新项目。核心将监督新核心的开发， “研究设计和分子流行病学”和“定制生理学和成像”。核心将管理 VCCBH预算，并在预算管理方面协助和教育PD（目标3）。核心A将协调 内部和外部咨询委员会，制定成果指标，并提供关于这些指标的半年度报告， PD、指导团队和咨询委员会（目标4）。最后，核心将提供跨 大学和超越中心的科学专长，核心资源和数据库，以及资源 由VCCBH生成（数据，标本，研究协议，新技术和研究结果）（目标5）。一 通信委员会将包括来自Larner通信办公室的专业人员 医学院和UVM基金会，以促进慈善事业。通过完成具体 我们的目标是：（1）推动4名早期职业科学家走向独立;（2）培养一个早期职业管道 科学家填补PD职位作为原始PD获得资金;（3）招募5名新的初级教师到UVM进入 我们未来的PD管道;（4）促进教师和实习生之间的合作， 心血管和神经血管的研究。