A Smartphone Intervention for Pregnancy Smoking Cessation with Peer Support

在同伴支持下通过智能手机干预怀孕戒烟

• 批准号: 10651998
• 负责人: KRISTIE L FOLEY
• 金额: $ 17.17万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10651998
• 关键词: Abstinence; Address; Adopted; Artificial Intelligence; Birth; Car Phone; Cellular Phone; Cessation of life; Clinical; Control Groups; Counseling; Couples; Development; Disease; Eastern Europe; Effectiveness; Friends; General Population; Goals; Health; Health Personnel; Health system; Healthcare; Human; Hybrids; Individual; International; Intervention; Knowledge; Learning; Methodology; Mission; Morbidity - disease rate; Outcome; Ownership; Persons; Phase; Population; Postpartum Period; Pregnancy; Pregnancy Tests; Pregnant Women; Prevention; Professional counselor; Psychological reinforcement; Public Health; Randomized; Research; Romania; Self Determination; Series; Smoke; Smoker; Smoking; Smoking Cessation Intervention; Spouses; Stress; System; Testing; Tobacco; Tobacco Use Cessation; Tobacco smoking behavior; United States National Institutes of Health; Woman; Work; acceptability and feasibility; adaptive learning; arm; base; behavior change; craving; design; effectiveness-implementation RCT; feasibility testing; iterative design; low and middle-income countries; mHealth; mobile computing; mortality; motivational enhancement therapy; novel; offspring; peer support; pilot trial; postnatal; prenatal; prenatal cigarette smoking; prepregnancy; programs; public health intervention; reproductive; smoking abstinence; smoking cessation; smoking during pregnancy; telephone coaching; theories; tobacco control; usability; user centered design; video coaching

PROJECT SUMMARY/ABSTRACT Tobacco smoking among women in Romania increased dramatically, by close to 30%, between 2011-2018 and the share of smokers with quit attempts decreased by 37%. Tobacco kills more than 8 million people a year around the world. The burden of tobacco-related illness and death is heaviest in low- and middle-income countries (LMICs) like Romania, where 80% of the worldwide 1.1 billion smokers live. Our work showed that 30% of women smoke pre-pregnancy in Romania and half of the smokers continue during pregnancy. It is critically important to address tobacco smoking during pregnancy, an extraordinary window of opportunity for sustained cessation. The objectives of this application are to develop, implement, and test the feasibility and effectiveness of an adaptive mobile pregnancy tobacco cessation app-based intervention using deep tailoring and a self-nominated support person, and to build mHealth research capacity in Romania. We build on our pregnancy smoking cessation trials with spousal support in Romania, including the ongoing Smoke Free Together (SFT1.0) mHealth pilot trial and the Quit Together telephone counseling trial that shows preliminary evidence of efficacy, and on our partnerships in Romania. The central hypothesis is that the intervention will show evidence of feasibility and effectiveness in increasing positive support, pregnancy cessation, and postnatal abstinence. The app will be novel in its use of the unique functionality of smartphones, use of reinforcement learning (RL) and deep tailoring to continuously adapt the intervention, the emphasis on increasing positive support, and the use of the app by both smoker and quit-partner. The aims are: 1. (R21 phase). Develop and test the feasibility and acceptability of the SFT2.0 app-based mobile smoking cessation intervention with quit-partner support during pregnancy and postpartum in Romania; 2. (R33 phase). Test the SFT2.0 app-based smoking cessation intervention in a hybrid effectiveness and implementation randomized controlled trial; 3. (R21 and R33 phases). Develop mHealth research capacity by enhancing individual and institutional research capabilities in Romania and expanding the existing international research network. With respect to expected outcomes, the proposed application is anticipated to advance understanding of the effectiveness and implementation of a smartphone-based app for pregnancy smoking cessation with quit- partner support. Such results are anticipated to have a system wide sustainable positive impact on the prevention of prenatal and postnatal smoking as the intervention has a high potential to be adopted in the universal health system in Romania, with applications to the US and other populations. The development of the international research network and the individual and institutional mHealth research capacity building is expected to positively impact mHealth research in CEE and the neighboring region.

项目概要/摘要 2011 年至 2018 年间，罗马尼亚女性吸烟率急剧上升，接近 30% 尝试戒烟的吸烟者比例下降了 37%。烟草每年导致超过 800 万人死亡 世界各地的一年。低收入和中等收入人群与烟草相关的疾病和死亡的负担最重 罗马尼亚等国家（中低收入国家）生活在全球 11 亿烟民中的 80%。我们的工作表明 在罗马尼亚，30% 的女性在怀孕前吸烟，一半的吸烟者在怀孕期间继续吸烟。这是 解决怀孕期间吸烟问题至关重要，这是一个非同寻常的机会之窗 持续停止。该应用程序的目标是开发、实施和测试可行性和 使用深度定制的基于自适应移动怀孕戒烟应用程序的干预措施的有效性 和一名自我提名的支持人员，并在罗马尼亚建立移动医疗研究能力。我们建立在我们的 罗马尼亚在配偶支持下进行的怀孕戒烟试验，包括正在进行的无烟活动 Together (SFT1.0) mHealth 试点试验和 Quit Together 电话咨询试验显示了初步结果 有效性的证据以及我们在罗马尼亚的伙伴关系。中心假设是干预将 展示增加积极支持、终止妊娠的可行性和有效性的证据，以及 产后禁欲。该应用程序的新颖之处在于它利用了智能手机的独特功能， 强化学习（RL）和深度定制以不断调整干预措施，强调 增加吸烟者和戒烟伴侣的积极支持以及该应用程序的使用。目标是： 1.（R21 阶段）。开发并测试基于SFT2.0应用程序的移动戒烟的可行性和可接受性 罗马尼亚在怀孕期间和产后通过戒烟伴侣支持进行干预； 2.（R33相）。测试 基于SFT2.0应用程序的戒烟干预混合有效性和随机实施 对照试验； 3.（R21 和 R33 相）。通过增强个人和 罗马尼亚的机构研究能力并扩大现有的国际研究网络。和 就预期成果而言，拟议的应用预计将增进对 基于智能手机的妊娠戒烟应用程序的有效性和实施 合作伙伴的支持。预计这些结果将对整个系统产生可持续的积极影响 预防产前和产后吸烟，因为该干预措施很有可能在儿童中采用 罗马尼亚的全民健康系统，适用于美国和其他人群。的发展 国际研究网络以及个人和机构移动医疗研究能力建设 预计将对中东欧及邻近地区的移动医疗研究产生积极影响。