Post-Doctoral Fellowship Training in HIV Clinical Investigation

该计划将加强以患者为导向的医生和科学家的HIV临床调查培训 坦桑尼亚西北部姆万扎的其他杰出临床医生。该计划建立在20年来 伙伴机构的协作和能力建设。坦桑尼亚的主要研究机构将 是姆万扎干预试验股(MITU)，这是坦桑尼亚国家医学研究所的一个单位 研究(NIMR)。MITU成立于2006年，是NIMR和伦敦学校的合作项目 卫生和热带医学研究所(LSHTM)加强坦桑尼亚的艾滋病毒干预研究。米图 与同样位于姆万扎的威尔·布甘多医学院密切合作。威尔 Bugando成立于2003年，旨在为坦桑尼亚西北部培训医生。米图和威尔·布甘多 自威尔·康奈尔医学院成立以来一直与其合作。 这一研究培训计划旨在填补姆万扎的一个关键空白：坦桑尼亚医生的需求 严格培训以患者为中心的HIV临床研究。我们使用NIH对临床的定义 研究是指在第一阶段、第二阶段或第二阶段直接与个别患者或成群患者互动的研究 临床试验、实用试验或形成性流行病学或行为研究，为临床做准备 审判。拟议培训方案的目标是：1.增加临床研究人员的数量 MITU，从而提高艾滋病毒临床研究的机构能力2.建立Weill Bugando/MITU 作为艾滋病毒临床研究的可持续培训中心。最终目标是预防新的艾滋病毒 提供有效的艾滋病毒护理，并改善坦桑尼亚和东非的艾滋病毒结果。 我们将为15名优秀的临床科学家提供长期培训，以指导以患者为导向的艾滋病毒 临床调查。我们将主要培训医生，但也将培训优秀的其他临床医生(PharmD、 DMD)。我们将培养10名博士和5名硕士研究生。坦桑尼亚学员将从参与中受益 在艾滋病毒调查的五个协同领域的17个积极研究项目中，包括艾滋病毒预防和 疫苗研究，艾滋病毒检测和治疗的实施，妇女健康，艾滋病毒相关联合感染，以及 艾滋病毒和心血管疾病。我们还将在威尔加强临床研究方面的博士课程 Bugando通过引入4门新的临床研究研究生课程。威尔·康奈尔致力于 机构资金，使4名最好的博士毕业生可以获得为期2年的博士后职位 米图研究科学家结束了他们的Fogarty培训。在为期5年的培训计划结束后，Mitu将拥有 一支临床研究队伍和更大的深度和广度的外部资助面向艾滋病毒患者 研究。Mitu/Weill Bugando将成为东非艾滋病毒临床研究人员的培训中心。

The program will strengthen patient-oriented HIV clinical investigation training of physician-scientists and other exceptional clinicians in Mwanza, in northwestern Tanzania. The program builds upon two decades of collaboration and capacity building by the partner institutions. The primary research institution in Tanzania will be the Mwanza Intervention Trials Unit (MITU), which is a unit of Tanzania’s National Institute for Medical Research (NIMR). MITU was established in 2006 as a collaboration between NIMR and the London School of Hygiene and Tropical Medicine (LSHTM) to strengthen HIV interventional research in Tanzania. MITU collaborates closely with the Weill Bugando School of Medicine, which is also located in Mwanza. Weill Bugando was established in 2003 to train physicians for northwestern Tanzania. MITU and Weill Bugando have collaborated with Weill Cornell Medical College since their founding. This research training program aims to fill a critical gap in Mwanza: the need for Tanzanian physicians with rigorous training in patient-oriented HIV clinical investigation. We use the NIH definition of clinical investigation as research which directly interacts with individual patients or clusters of patients in Phase I, II, or III clinical trials, pragmatic trials, or formative epidemiologic or behavioral research in preparation for clinical trials. The goals of the proposed training program are: 1.To increase the number of clinical investigators at MITU and thereby increase institutional capacity for HIV clinical investigation 2. Establish Weill Bugando/MITU as a sustainable training center for HIV clinical investigation. The ultimate goal is to prevent new HIV infections, provide effective HIV care, and improve HIV outcomes in Tanzania and East Africa. We will provide long-term training to fifteen outstanding clinician scientists to conduct patient-oriented HIV clinical investigation. We will primarily train physicians but will also train exceptional other clinicians (PharmD, DMD). We will train 10 PhDs, and 5 MS degree candidates. Tanzanian trainees will benefit from participation in 17 active research projects in five synergistic areas of HIV investigation including HIV prevention and vaccine research, implementation of HIV testing and treatment, women’s health, HIV related co-infections, and HIV and cardiovascular disease. We will also strengthen the PhD program in clinical investigation at Weill Bugando by introducing 4 new graduate courses in clinical investigation. Weill Cornell is committing institutional funds so that 4 of the best PhD graduates can have 2-year post-doctoral appointments as MITU research scientists after their Fogarty training. At the end of the 5-year training program, MITU will have a cadre of clinical investigators and a greater depth and breadth of externally funded HIV patient-oriented research. MITU/Weill Bugando will be a training hub for HIV clinical investigators in East Africa.