Accelerated Telomere Length Attrition Rate in Diabetes and Its Cellular Mechanism

糖尿病端粒长度加速损耗及其细胞机制

• 批准号: nhmrc : 1039863
• 负责人: Mr Surya Sutanto
• 金额: $ 2.56万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/accelerated-telomere-length-cellular-mechanism/111311
• 关键词: Accelerated; Telomere; Length; Attrition; Rate

I am a PhD in Medicine-University of Sydney. My research focus is about telomere dynamic, its mechanism and correlation between telomere length and diabetes attributes. I will compare telomere length between different diabetes groups & examine telomere regulation in cell culture/animal model to compliment my clinical data. The hypothesis: accelerated telomere shortening may co-segregate with diabetes complications and by preserving telomere we could potentially prevent adverse effect of diabetes

我是悉尼大学的医学博士。我的研究重点是端粒动态、其机制以及端粒长度与糖尿病属性的相关性。我将比较不同糖尿病组之间的端粒长度，并在细胞培养/动物模型中检查端粒调节，以补充我的临床数据。假设：加速的端粒缩短可能与糖尿病并发症共同分离，通过保留端粒，我们可能会预防糖尿病的不利影响。