Catalyzing and Harmonizing Operational Innovation for Recruitment (CHOIR)

促进和协调招聘运营创新 (CHOIR)

基本信息

  • 批准号:
    10649341
  • 负责人:
  • 金额:
    $ 535.76万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-07-14 至 2028-04-30
  • 项目状态:
    未结题

项目摘要

While recruitment into clinical research has been a longstanding challenge for NIH funded multi-site studies, it has become clear that there is substantial variability in recruitment success across the national portfolio caused by many factors: eligibility parameters, required procedures, compensation levels, engagement practices, recruitment resources, skill and awareness of recruitment teams, geographic constraints, trust, and perceived benefit/risk. Studies that do not integrate these factors into recruitment and retention often close for poor accrual. In addition, there are now more equitable definitions of what constitutes “recruitment success” beyond an absolute target, including: diversity, representativeness of the actual population, costs of enrollment, retention, and time required. These complex dynamics suggest there is no ‘one size fits all’ solution, and careful attention and consideration must be a part of the recruitment plan. Our team has been forming effective recruitment collaborations for the past 6 years -- considering the study specifics, capabilities of the study team, and needs and values of the participant population -- to together craft feasible, effective plans. In the next cycle, we will Catalyze and Harmonize Operational Innovation for Recruitment (CHOIR) and will continue to be led by a long-standing synergistic partnership between Paul Harris, PhD, as PI responsible for informatics development, and Consuelo Wilkins, MD, MSCI, as PI of community and stakeholder engagement. Formal partnerships with 10 other CTSAs provide broad understanding of Hub needs, along with key areas of expertise. We will extend and build upon existing recruitment-related assets and data tools and resources already in use by our team and others (FasterTogether, ResearchMatch, REDCap TrialsToday, FHIR clinical data-based recruitment infrastructure). These innovations acknowledge recruitment is not a one-time activity but is a continuum. We will provide a national, disease agnostic home for sharing recruitment tools, training, materials, and best practices for diverse populations. Specific Aims are: 1) Partner with study teams to create study-specific recruitment plans, and support ongoing skills development. 2) Evaluate clinical trial recruitment and retention methods and make continual improvements. 3) Enhance national clinical trial awareness through engagement and education; facilitate participant identification of studies with online tools. And, 4) Develop and disseminate technical and procedural approaches to catalyze enrollment in clinical trials across all CTSAs.
虽然临床研究的招募一直是 NIH 资助的多中心研究的一个长期挑战, 很明显,整个国家组合的招聘成功率存在很大差异 由多种因素引起:资格参数、所需程序、薪酬水平、参与度 实践、招聘资源、招聘团队的技能和意识、地理限制、信任和 感知的利益/风险。没有将这些因素纳入招聘和保留的研究通常会结束 由于应计收益不佳。此外,现在对于“招聘”的构成有了更公平的定义。 超越绝对目标的成功”,包括:多样性、实际人口的代表性、 注册、保留和所需时间。这些复杂的动态表明不存在“一刀切”的方法 解决方案,并且认真关注和考虑必须成为招聘计划的一部分。我们的团队已经 在过去 6 年中形成有效的招聘合作——考虑到研究的具体情况、能力 研究团队的意见以及参与者的需求和价值观——共同制定可行、有效的方案 计划。在下一个周期中,我们将促进和协调招聘运营创新(CHOIR) 并将继续由 PI 保罗·哈里斯博士之间的长期协同合作伙伴关系领导 负责信息学开发,Consuelo Wilkins(医学博士、MSCI)担任社区和 利益相关者的参与。与其他 10 个 CTSA 的正式合作伙伴关系提供了对 Hub 的广泛了解 需求以及关键专业领域。我们将扩展和利用现有的招聘相关资产 以及我们的团队和其他人已经在使用的数据工具和资源(FasterTogether、ResearchMatch、 REDCap TrialsToday,FHIR 基于临床数据的招募基础设施)。这些创新承认 招聘不是一次性的活动,而是一个连续的过程。我们将提供一个全国性的、与疾病无关的家园 为不同人群分享招聘工具、培训、材料和最佳实践。具体目标 包括:1) 与研究团队合作制定针对研究的招募计划,并支持持续的技能 发展。 2)评估临床试验招募和保留方法并持续改进。 3)通过参与和教育提高国家临床试验意识;方便参与者 使用在线工具识别研究。并且,4) 开发和传播技术和程序 促进所有 CTSA 临床试验注册的方法。

项目成果

期刊论文数量(0)
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专利数量(0)

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Paul A. Harris其他文献

Electronic data capture system (REDCap) for healthcare research and training in a resource-constrained environment: Adoption and growth at a South African institution (Preprint)
用于资源有限环境中医疗保健研究和培训的电子数据采集系统 (REDCap):南非机构的采用和发展(预印本)
  • DOI:
    10.2196/preprints.33402
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Irma Adele Maré;B. Kramer;S. Hazelhurst;M. Nhlapho;R. Zent;Paul A. Harris;M. Klipin
  • 通讯作者:
    M. Klipin
Lentivirally-delivered superoxide dismutase 2 gene therapy in free flaps protects against the late adverse effects of radiotherapy
  • DOI:
    10.1016/j.bjps.2014.09.005
  • 发表时间:
    2014-11-01
  • 期刊:
  • 影响因子:
  • 作者:
    Aadil A. Khan;Martin McLaughlin;Joan Kyula;Michelle Wilkinson;Paul A. Harris;Kevin J. Harrington
  • 通讯作者:
    Kevin J. Harrington
Data from the All of Us research program reinforces existence of activity inequality
“我们所有人”研究项目的数据强化了活动不平等的存在。
  • DOI:
    10.1038/s41746-024-01358-4
  • 发表时间:
    2025-01-04
  • 期刊:
  • 影响因子:
    15.100
  • 作者:
    Hayoung Jeong;Ali R. Roghanizad;Hiral Master;Juseong Kim;Aymone Kouame;Paul A. Harris;Melissa Basford;Kayla Marginean;Jessilyn Dunn
  • 通讯作者:
    Jessilyn Dunn
Application of Information Technology: Clinical Research Subject Recruitment: The Volunteer for Vanderbilt Research Program www.volunteer.mc.vanderbilt.edu
信息技术的应用:临床研究受试者招募:范德比尔特研究计划志愿者 www.volunteer.mc.vanderbilt.edu
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Paul A. Harris;Lynda D. Lane;Italo Biaggioni
  • 通讯作者:
    Italo Biaggioni
Therapeutic free flaps – Transducing the flap with viral vectors to treat resected tumour beds of macroscopic and microscopic residual disease
  • DOI:
    10.1016/j.bjps.2014.08.028
  • 发表时间:
    2014-10-01
  • 期刊:
  • 影响因子:
  • 作者:
    Rohit Seth;Aadil Khan;Tim Pencavel;Kevin J. Harrington;Paul A. Harris
  • 通讯作者:
    Paul A. Harris

Paul A. Harris的其他文献

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{{ truncateString('Paul A. Harris', 18)}}的其他基金

ICERCH-Supporting the HEAL Pain ERN
ICERCH-支持 HEAL Pain ERN
  • 批准号:
    10709590
  • 财政年份:
    2022
  • 资助金额:
    $ 535.76万
  • 项目类别:
STEPS: Supporting Trials for Effective Pain Solutions
步骤:支持有效疼痛解决方案的试验
  • 批准号:
    10887940
  • 财政年份:
    2022
  • 资助金额:
    $ 535.76万
  • 项目类别:
ICERCH-Supporting the HEAL Pain ERN
ICERCH-支持 HEAL Pain ERN
  • 批准号:
    10592520
  • 财政年份:
    2022
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH)
改善 CTSA 中心的临床试验教育、招募和注册 (I-CERCH)
  • 批准号:
    9114803
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH)
改善 CTSA 中心的临床试验教育、招募和注册 (I-CERCH)
  • 批准号:
    9353931
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH)
改善 CTSA 中心的临床试验教育、招募和注册 (I-CERCH)
  • 批准号:
    10191693
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH) - HEAL Supplement
改善 CTSA 中心 (I-CERCH) 的临床试验教育、招募和注册 - HEAL 补充
  • 批准号:
    10656029
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH)
改善 CTSA 中心的临床试验教育、招募和注册 (I-CERCH)
  • 批准号:
    10438094
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH)
改善 CTSA 中心的临床试验教育、招募和注册 (I-CERCH)
  • 批准号:
    10065731
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH)
改善 CTSA 中心的临床试验教育、招募和注册 (I-CERCH)
  • 批准号:
    10158963
  • 财政年份:
    2016
  • 资助金额:
    $ 535.76万
  • 项目类别:

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