Molecular Basis of Infectious Diseases Training Grant
Molecular Basis of Infectious Diseases Training Grant
批准号:
10662391
负责人:
Michael C Lorenz
金额:
$17.87万
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
未结题
起止时间:
2005-09-15 至 2026-07-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
PROJECT SUMMARY/ABSTRACT
Enhanced training in infectious disease-related research is critical for the generation of new knowledge that
can be applied to the treatment and prevention of clinical problems. In this long-standing training program,
Molecular Basis of Infectious Diseases (MBID), we focus on the development of microbiologists with the
skills to advance our understanding of molecular biology, microbiology, bacterial and fungal pathogens, and
host-microbe interactions, and the ability to recognize opportunities for translation of that information into
clinical applications. The purpose of the MBID T32 is to 1) provide an optimal environment for training new
scientists in the latest concepts and techniques in microbiological research; 2) enhance the understanding
among young scientists of current challenges in clinical infectious diseases; and 3) teach critical thinking skills
that prepare students for research careers in which they contribute to and influence research efforts that lead
to effective solutions for important infectious disease problems. The 21 diverse faculty members participating in
the renewal of this predoctoral training grant are from five partner and neighboring institutions: University of
Texas Health Science Center at Houston, MD Anderson Cancer Center, Baylor College of Medicine, Rice
University and Institute of Biosciences and Technology of Texas A&M University. Our faculty have a record of
high research productivity, extensive collaborations, investigator-initiated NIH funding, and graduate student
and postdoctoral fellow training. They have mentored 80 predoctoral trainees during the past ten years, and
currently are mentoring 47 PhD students. The training program includes a core curriculum that draws upon
relevant courses at participating institutions, intensive and interactive research experiences, monthly MBID
meetings, annual retreats, weekly seminars and journal clubs, career and professional development activities,
interaction with underrepresented summer undergraduate students, and participation in infectious disease
grand rounds. The MBID faculty have a strong track record in the recruitment, training, and career
advancement of underrepresented groups. For the next grant period, enhancement of the successful MBID
predoctoral training with an improved curriculum, additional training faculty, and the addition of a predoc–
postdoc mentoring program are proposed. The training program will undergo regular evaluations by external
experts and adjustments made to the program as needed. MBID takes advantage of the strong research and
mentoring expertise of its faculty and the educational activities already in place and to leverage all the available
resources to train the next generation of scientists focused on tackling pressing infectious disease and public
health issues. The highly collaborative environment provides the perfect opportunity for trainees to acquire the
skills, expertise and intellectual abilities to foster innovative research and prepare them for careers in which
they contribute to effective solutions for important infectious disease problems.
期刊论文(14)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1038/s41598-023-33178-z
发表时间:
2023-04-18
期刊:
SCIENTIFIC REPORTS
影响因子:
4.6
作者:
[Taylor, John Culver, Kumar, Ritesh, Xu, Juan, Xu, Yi]
通讯作者:
Xu, Yi
In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
对苯基咪唑对艰难梭菌烯酰-ACP 还原酶 II (FabK) 抑制作用的体内评估揭示了一种有前景的窄谱抗菌策略。
DOI:
10.1101/2023.09.22.559005
发表时间:
2023
期刊:
bioRxiv : the preprint server for biology
影响因子:
--
作者:
[Dureja,Chetna, Rutherford,JacobT, Pavel,FahadBA, Norseeda,Krissada, Prah,Isaac, Sun,Dianqing, Hevener,KirkE, Hurdle,JulianG]
通讯作者:
Hurdle,JulianG
DOI:
10.1039/c3mt00288h
发表时间:
2014-03
期刊:
Metallomics : integrated biometal science
影响因子:
--
作者:
[Latorre M, Galloway-Peña J, Roh JH, Budinich M, Reyes-Jara A, Murray BE, Maass A, González M]
通讯作者:
González M
Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agents.
新型Anti-C苯基咪唑FabK抑制剂的合成与评价。
DOI:
10.1016/j.bmc.2023.117330
发表时间:
2023
期刊:
Bioorganic & medicinal chemistry
影响因子:
3.5
作者:
[Norseeda,Krissada, BinAzizPavel,Fahad, Rutherford,JacobT, Meer,HumnaN, Dureja,Chetna, Hurdle,JulianG, Hevener,KirkE, Sun,Dianqing]
通讯作者:
Sun,Dianqing
Unraveling the role of host endocytic proteins in pedestal formation during enteropathogenic Escherichia coli infection.
揭示宿主内吞蛋白在肠致病性大肠杆菌感染期间基座形成中的作用。
DOI:
10.1093/infdis/jir391
发表时间:
2011
期刊:
The Journal of infectious diseases
影响因子:
--
作者:
[Darkoh,Charles, DuPont,HerbertL]
通讯作者:
DuPont,HerbertL
共 6 条
Characterization of novel virulence factors in Candida
-
批准号:10540739
-
项目类别:
-
资助金额:$32.1万
-
财政年份:2019
-
负责人:Michael C Lorenz
-
依托单位:
Characterization of novel virulence factors in Candida
-
批准号:9765613
-
项目类别:
-
资助金额:$52.58万
-
财政年份:2019
-
负责人:Michael C Lorenz
-
依托单位:
Characterization of novel virulence factors in Candida
-
批准号:10319584
-
项目类别:
-
资助金额:$52.12万
-
财政年份:2019
-
负责人:Michael C Lorenz
-
依托单位:
FASEB SRC on Molecular Pathogenesis: Mechanisms of Infectious Disease
-
批准号:9331802
-
项目类别:
-
资助金额:$0.5万
-
财政年份:2017
-
负责人:Michael C Lorenz
-
依托单位:
The role of ATO function in fungal pathogenesis
-
批准号:9127551
-
项目类别:
-
资助金额:$19.25万
-
财政年份:2016
-
负责人:Michael C Lorenz
-
依托单位:
Virulence factor identification by comparative transcriptomics in Candida species
-
批准号:8646883
-
项目类别:
-
资助金额:$19.0万
-
财政年份:2013
-
负责人:Michael C Lorenz
-
依托单位:
Virulence factor identification by comparative transcriptomics in Candida species
-
批准号:8493140
-
项目类别:
-
资助金额:$22.8万
-
财政年份:2013
-
负责人:Michael C Lorenz
-
依托单位:
Roles of acetate metabolism in the virulence of Candida albicans
-
批准号:8137392
-
项目类别:
-
资助金额:$5.85万
-
财政年份:2010
-
负责人:Michael C Lorenz
-
依托单位:
Understanding Immunomodulation by Candida albicans
-
批准号:7382437
-
项目类别:
-
资助金额:$18.46万
-
财政年份:2008
-
负责人:Michael C Lorenz
-
依托单位:
Understanding Immunomodulation by Candida albicans
-
批准号:7634500
-
项目类别:
-
资助金额:$18.75万
-
财政年份:2008
-
负责人:Michael C Lorenz
-
依托单位:
Extracellular pH modulation by Candida albicans in vitro and in vivo
-
批准号:8847274
-
项目类别:
-
资助金额:$44.32万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Roles of acetate metabolism in the virulence of Candida albicans
-
批准号:8077298
-
项目类别:
-
资助金额:$35.46万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Extracellular pH modulation by Candida albicans in vitro and in vivo
-
批准号:9269129
-
项目类别:
-
资助金额:$42.03万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Roles of acetate metabolism in the virulence of Candida albicans
-
批准号:7431609
-
项目类别:
-
资助金额:$36.18万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Roles of acetate metabolism in the virulence of Candida albicans
-
批准号:7627206
-
项目类别:
-
资助金额:$36.18万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Extracellular pH modulation by Candida albicans in vitro and in vivo
-
批准号:9205371
-
项目类别:
-
资助金额:$2.41万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Extracellular pH modulation by Candida albicans in vitro and in vivo
-
批准号:9059545
-
项目类别:
-
资助金额:$44.2万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Extracellular pH modulation by Candida albicans in vitro and in vivo
-
批准号:8903815
-
项目类别:
-
资助金额:$5.05万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Extracellular pH modulation by Candida albicans in vitro and in vivo
-
批准号:8578271
-
项目类别:
-
资助金额:$35.34万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
Roles of acetate metabolism in the virulence of Candida albicans
-
批准号:7301708
-
项目类别:
-
资助金额:$36.59万
-
财政年份:2007
-
负责人:Michael C Lorenz
-
依托单位:
海外基金