Project 3: Nicotine Product Claims on Appeal, Perceptions, and Use Behavior

项目 3：尼古丁产品声称的吸引力、认知和使用行为

• 批准号: 10666069
• 负责人: Darren M Mays
• 金额: $ 46.42万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-14 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10666069
• 关键词: Address; Adult; Affect; Behavior; Behavioral; Cigarette; Cognitive; Color; Communication; Dependence; Dimensions; Electronic cigarette; Future; Goals; Harm Reduction; Human; Industry; Label; Laboratories; Marketing; Measures; Methods; Modified Risk Tobacco Product; Nicotine; Nicotine Dependence; Ohio; Oral; Perception; Persons; Predisposition; Proliferating; Psychophysiology; Public Health; Regulation; Risk; Sales; Sampling; Science; Smokeless Tobacco; Smoker; Source; Tobacco; Tobacco Industry; Toxic effect; Universities; Visual; abuse liability; behavior measurement; behavioral economics; design; experimental study; innovation; interest; laboratory experiment; novel; novel strategies; preference; risk perception; smokeless tobacco user; tobacco products; tobacco regulatory science; tobacco user; tobacco-free; tool; young adult

SUMMARY – PROJECT 3 Oral nicotine pouches (ONPs) emerged in the U.S. in 2016, ONP brands rapidly proliferated, and sales are skyrocketing. ONPs are representative of a shift by the tobacco industry to marketing non-tobacco nicotine products as alternatives to cigarettes, smokeless tobacco (ST), and even e-cigarettes (ECs). Nicotine is the driver of use and dependence, and the industry continuously manipulates nicotine dimensions to maximize appeal to consumers. Packaging is a primary marketing vehicle to increase product appeal, and ONP packaging prominently emphasizes nicotine concentration (e.g., 3 mg, 6 mg) and source claims (e.g., “tobacco free”) as a marketing tool. Understanding how these packaging features communicating nicotine dimensions affect the appeal of ONPs in young adult non-users versus adult tobacco users is critical to inform regulations for ONPs and other nicotine products using similar marketing. Project 3 of the Ohio State University Tobacco Center of Regulatory Science (OSU-TCORS) will examine how nicotine concentration and source claims on ONP packaging affect the appeal of ONPs and how these features affect preferences for ONPs relative to ECs, cigarettes, ST, and other products in young non-tobacco users versus adult tobacco users. The Specific Aims are to: 1) Examine the effects of nicotine concentration and source claims on visual and cognitive engagement with ONP packaging using laboratory-based psychophysiological assessment. 2) Examine the effects of nicotine concentration and source claims on ONP perceptions, behavioral intentions, and ONP trial. 3) Investigate the effects of nicotine concentration and source claims on ONP preferences relative to ECs, cigarettes, ST, and other tobacco products. Project 3 includes 2 complementary studies to accomplish these aims. Study 1 (Aims 1 and 2) is a 2 (young adult susceptible non-user, adult tobacco user) x 3 (labelled nicotine concentration: none, low, high) x 3 (source claim: none, “tobacco free,” “synthetic”) human laboratory experiment to examine how nicotine concentration and source claims affect engagement with ONP packaging using psychophysiological measures, ONP appeal, risk perceptions and use intentions, and a behavioral lapse task assessing ONP trial. Study 2 (Aim 3) is a discrete choice experiment with a national sample of young adult susceptible non-users and adult tobacco users to assess the effects of nicotine concentration and source claims on ONP preferences relative to ECs, cigarettes, ST, and other products. Project 3 addresses the Marketing Influences and Behavior FDA tobacco regulatory science domains. Project 3 is significant and innovative because it will be one of the first studies to generate evidence to inform potential regulation of packaging features communicating nicotine concentration and nicotine source claims based on their differential effects in young adult non-users versus adult tobacco users. Through integration with Projects 1, 2, and 4, the OSU-TCORS will provide evidence to guide an overall regulatory strategy targeting nicotine dimensions for ONPs, ECs, and other novel products.

摘要--项目3 口腔尼古丁袋子(ONPs)于2016年出现在美国，ONP品牌迅速激增，销售 飞涨。ONPs代表了烟草行业向销售非烟草尼古丁的转变 作为香烟、无烟烟草(ST)、甚至电子烟(EC)替代品的产品。尼古丁是 使用和依赖的驱动力，该行业不断操纵尼古丁维度，以最大限度地 吸引消费者。包装是增加产品吸引力的主要营销工具，而ONP包装 突出强调尼古丁浓度(如3毫克、6毫克)和来源声明(如“无烟草”)为 一种营销工具。了解这些包装传递尼古丁维度的功能如何影响 年轻成年非吸烟者与成年烟草使用者对ONPs的吸引力是制定ONPs法规的关键 以及其他使用类似营销的尼古丁产品。俄亥俄州立大学烟草中心项目3 监管科学(OSU-TCORS)将研究尼古丁浓度和来源对ONP的声明 包装影响ONPs的吸引力，以及这些特征如何影响ONPs相对于ECs的偏好， 香烟、ST和其他产品在年轻的非烟草使用者和成年烟草使用者之间的比较。具体目标 是为了：1)检查尼古丁浓度和来源声称对视觉和认知投入的影响 使用ONP包装使用基于实验室的心理生理学评估。2)检查尼古丁的影响 关于ONP认知、行为意图和ONP试验的注意力和来源主张。3)调查 尼古丁浓度和来源声明对ONP相对于ECs、香烟、ST和 其他烟草产品。项目3包括两项相辅相成的研究以实现这些目标。研究1(目标 1和2)是2(年轻人易受影响的非吸烟者，成年烟草吸烟者)×3(标记尼古丁浓度：无， 低，高)x 3(来源：无，“无烟草”，“合成”)人体实验室实验，以检查如何 尼古丁浓度和来源声称使用心理生理学影响与ONP包装的接触 衡量标准、ONP诉求、风险认知和使用意图，以及评估ONP试验的行为失误任务。 研究2(目标3)是一项离散选择实验，在全国范围内抽样调查易感非吸毒者和 成年烟草使用者评估尼古丁浓度和来源声明对ONP偏好的影响 相对于ECS、香烟、ST和其他产品。项目3介绍营销的影响和行为 FDA烟草管理科学领域。项目3具有重大意义和创新性，因为它将是 首次研究产生证据，为传递尼古丁的包装特征的潜在监管提供信息 浓度和尼古丁来源声称基于它们在年轻成人非吸烟者和成年人中的不同影响 吸烟者。通过与项目1、2和4的集成，OSU-TCORS将提供证据以指导 针对ONPs、ECs和其他新产品的尼古丁维度的整体监管战略。