Administrative Core

行政核心

• 批准号: 10664013
• 负责人: John T West
• 金额: $ 80.1万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10664013
• 关键词: Academic Medical Centers; Achievement; Advisory Committees; Affect; Awareness; Basic Science; Bioinformatics; Biomedical Research; Cancer Center; Cancer Etiology; Centers of Research Excellence; Clinical; Clinical Research; Clinical Sciences; Clinical Trials Unit; Collaborations; Computerized Medical Record; Core Facility; Dedications; Development; Development Plans; Economics; Educational process of instructing; Ensure; Environment; Equity; Ethnic Origin; Evaluation; Funding; Future; Gender; Grant; Health; Health Sciences; Homeostasis; Institution; Instruction; Interdisciplinary Study; International; Journals; Leadership; Louisiana; Malignant - descriptor; Malignant Neoplasms; Manuscripts; Mentors; Modality; Morbidity - disease rate; NCI Center for Cancer Research; Newsletter; Oncology; Patient Care; Patient-Focused Outcomes; Patients; Peer Review; Phase; Pilot Projects; Preventive; Process; Productivity; Program Development; Research; Research Personnel; Research Project Grants; Research Proposals; Research Support; Resources; Role; Scientist; Strategic Planning; Structure; Teacher Professional Development; Techniques; Testing; Therapeutic; Training; Translational Research; Translations; Universities; Viral; Viral Cancer; Virus; career development; community engagement; design; experience; forging; health disparity populations; improved; improved outcome; interest; meetings; minority patient; mortality; novel; operation; patient population; programs; research study; tumor registry; virus host interaction; virus related cancer

Abstract: The Administrative Core (AC) will support the Program Director of the Center for Translational Viral Oncology (CTVO) during its Phase 2 operation by providing the overall planning and coordination of the mentoring and research for the selected group of Junior Principle Investigators (PJIs). The AC will be responsible for managing the day-to-day operations of the Center, organizing advisory committee meetings, facilitating JPIs privileged access to research core facilities, evaluating new pilots and research projects, and promoting interdisciplinary interactions. This will ensure an appropriate career development for JPIs who have a strong interest in utilizing their most important research findings for the development of new preventive and/or therapeutic modalities against virus-associated cancers. There are three major factors which make the CTVO highly competitive and unique: 1) Access to a unique minority patient population that is disproportionally affected by virus-induced cancers; 2) Experienced basic research and clinical scientists who are dedicated to the study of viral cancers and are highly motivated to serve as mentors and advisors in CTVO; and 3) State-of-the-art Research Core Facilities. The AC is designed specifically to facilitate each of these crucial components through the following specific aims: Aim 1: Provide scientific leadership and administrative structure for coordinating thematic research on viruses and cancer across participating institutions, including peer review from internal and external advisors, and for integration of CTVO with other programs dedicated to research, patient care, teaching, and community engagement. Aim 2: Support the development of highly competitive Principal Junior Investigators (JPIs) through mentoring and career development plans within the CTVO and their Academic Departments. Aim 3: Promote the development, sustainability, and effective utilization of research core facilities, novel scientific techniques and resources while instilling an awareness and sensitivity to gender, economic and ethnic inclusiveness, and equity in all activities. The participating institutions include Louisiana State University Health Sciences Center (LSUHSC), New Orleans; LSUHSC, Baton Rouge; LSUHSC, Shreveport; and Tulane University Medical Center (TUMC), which are responsible for the majority of patient care, research, and scientific training in the region. These institutions support state-of-the-art core facilities, tumor registries, electronic medical records, clinical trial units and bioinformatics. We have engaged these valuable institutional resources and have selected outstanding basic research and clinical mentors to create this highly motivating and competitive research environment for COBRE-supported JPI candidates.

翻译后摘要：行政核心（AC）将支持该中心的项目主任， 转化病毒肿瘤学（CTVO）在其2期手术期间，通过提供 规划和协调的指导和研究的初级原则的选定组 调查员。审计委员会将负责管理 中心，组织咨询委员会会议，促进JPI特权访问研究 核心设施，评估新的试点和研究项目，并促进跨学科 交互.这可确保具备良好专业知识的太平绅士， 有兴趣利用他们最重要的研究成果开发新的预防性药物 和/或针对病毒相关癌症的治疗方式。有三大因素 这使得CTVO具有高度的竞争力和独特性：1）获得独特的少数民族患者 受病毒诱导的癌症影响的人群; 2）经历过基本的 致力于研究病毒性癌症的研究和临床科学家， 有动力在CTVO担任导师和顾问;以及3）最先进的研究核心 设施AC专门设计用于促进这些关键组件中的每一个， 目标1：提供科学的领导和行政结构， 协调各参与机构关于病毒和癌症的专题研究，包括 内部和外部顾问的同行评审，以及CTVO与其他计划的整合 致力于研究，病人护理，教学和社区参与。目标2：支持 通过指导和培训，培养极具竞争力的初级首席调查员， CTVO及其学术部门的职业发展计划。目标3：促进 发展，可持续性和有效利用研究核心设施，新的科学 同时灌输对性别、经济和社会问题的认识和敏感性， 种族包容和所有活动的公平。参与机构包括路易斯安那州 州立大学健康科学中心，新奥尔良; LSUHSC、什里夫波特和杜兰大学医学中心（TUMC），负责 该地区的大部分病人护理、研究和科学培训。这些机构 支持最先进核心设施、肿瘤登记、电子病历、临床试验 单位和生物信息学。我们利用了这些宝贵的机构资源， 选择优秀的基础研究和临床导师，创造这个高度激励和 竞争激烈的研究环境COBRE支持的JPI候选人。