Supplement for CSULB Maximizing Access to Research Careers (MARC) UNDERGRADUATE STUDENT TRAINING IN ACADEMIC RESEARCH (U-STAR)

CSULB 最大限度地获得研究职业的补充 (MARC) 本科生学术研究培训 (U-STAR)

• 批准号: 10559019
• 负责人: VASANTHY NARAYANASWAMI
• 金额: $ 3.68万
• 依托单位: CALIFORNIA STATE UNIVERSITY LONG BEACH
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-06-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10559019
• 关键词: Academic Training; Academic support; Area; Award; Behavioral Research; Biomedical Research; California; Consultations; Counseling; Critical Thinking; Discipline; Education; Educational Curriculum; Ensure; Environment; Equilibrium; Face; Faculty; Fostering; Funding; Goals; Human Resources; Institutes; K-Series Research Career Programs; Leadership; Mathematics; Mentors; National Institute of General Medical Sciences; Natural Sciences; Parents; Process; Research; Research Project Grants; Research Training; Schools; Science; Spottings; Strategic Planning; Students; System; Time; Training; Training Activity; Training Programs; Training Support; Travel; United States National Institutes of Health; Universities; Wages; base; career; college; competitive environment; experience; faculty mentor; graduate school preparation; leadership development; member; operation; programs; skills; student training; summer research; symposium; training opportunity; undergraduate research; undergraduate student; underserved students

SUMMARY CSULB MARC Undergraduate Student Training in Academic Research (U*STAR) Program The current proposal is a Supplement to the existing parent award, California State University Long Beach (CSULB) Maximizing Access to Research Careers (MARC) Undergraduate Student Training in Academic Research (U*STAR) Program (NIH T34 GM008074) (06/01/2017-05/31/2022). The overall scope and objectives of the supplement are aligned with those of the parent award with a goal to continue to increase the number of under-served students entering and earning doctorates in biomedical sciences. The parent award supports 10 MARC Scholars who receive enhanced academic and research training for 2 years to prepare them to enter and succeed in graduate programs in biomedical and behavioral research areas. At the end of the current cycle (05/31/2022), five MARC Scholars are expected to continue their second year of training for which additional funding is needed ($ 231,813). As of 05/31/2022, the unobligated balance is estimated to be $ 85,698. The current proposal seeks supplemental funding ($146,115) that will be used in conjunction with the unobligated balance to successfully continue the program operation and complete the training process of the five students (Avalos, Chen, Nguyen, Phan and Skorka), who are already listed in the eRA Commons X-Train system. The funds will be used to support the 5 trainees’ stipend and partial tuition, research supplies, travel to conferences and off-campus summer research experience in a research-intensive environment, in addition to providing partial salary support for the program personnel. The goal is to continue offering deeper and specific research training that will develop the technical, operational and professional skills, with a focus on strengthening the trainees’ quantitative abilities in existing courses and research training activities as described in the objectives of the parent award below. The 5 students are on track to graduate in May 2023 and are currently engaged in faculty-mentored research projects in which they are showing strong progress; in addition, they are preparing to apply for their off-campus research experience for summer 2022. All components of the one-year training supported by the supplement will be evaluated like the parent program. The objectives of the training program that will be supported by the supplement are to: (i) offer a rich, intense education experience through research-based, Honors curriculum, supplementary academic support, priority registration and counseling to the trainees to; (ii) provide an enriching research experience, in a mentored environment that fosters critical thinking; in addition, the Scholars will be required to participate in a short-term research experience in summer 2022 in a research-intensive institute; (iii) train MARC Scholars in professional and leadership development activities, and, (iv) encourage graduate school preparation. Taken together, the supplement will help in completing the training of the Scholars and lay the essential groundwork required for them to enter and face the rigors of graduate school education in a highly competitive atmosphere. Further, to continue offering research training opportunities after the current MARC T34 program has ended, the institute leadership (Dean and Associate Dean for Research of the College of Natural Sciences and Mathematics, and program directors of current CSULB MARC and RISE programs) has developed a strategic plan following consultation with the NIGMS Program Officers in spring 2021. It involves submission of a new NIGMS Undergraduate Research Training Initiative for Student Enhancement (U-RISE) (T34) in May 2022 (CSULB is eligible to apply for U-RISE based on its status as a research-active institute). The U-RISE leadership team has been identified and involves key personnel from current T34 MARC program. The plan is to request 30 spots for training undergraduate students from a diverse background with a proposed start date of 06/01/2023 if funded. The trainees will receive an enriching academic and research experience for two years, which will prepare them for graduate programs. They will carry out their research with faculty members from diverse backgrounds, disciplines and career stages. At the same time, we would request ending the ongoing RISE program (04/01/2020-03/31/2025) (with 20 funded spots) earlier than its projected end date (in consultation with NIH Program officials) so that there is no overlap with U-RISE. This will ensure continuous availability of research training opportunities for CSULB students. In summary, the supplement to the parent award is a critical requirement to complete the training of the five MARC Scholars. It is expected to have a lasting impact on their career decisions and entry into graduate programs in the biomedical field.

概括 CSULB MARC 本科生学术研究培训 (U*STAR) 计划 当前的提案是对现有家长奖的补充，加州州立大学长滩分校 (CSULB) 最大限度地获得研究职业机会 (MARC) 本科生学术培训 研究 (U*STAR) 计划 (NIH T34 GM008074) (06/01/2017-05/31/2022)。总体范围和 该补助金的目标与家长奖的目标一致，旨在继续提高 进入并获得生物医学科学博士学位的服务不足的学生数量。家长奖 支持 10 名 MARC 学者接受为期 2 年的强化学术和研究培训，为他们做好准备 他们进入生物医学和行为研究领域的研究生课程并取得成功。 在本周期结束时（2022 年 5 月 31 日），五名 MARC 学者预计将继续他们的第二年 需要额外资金的培训（231,813 美元）。截至 2022 年 5 月 31 日，未承付余额为 估计为85,698美元。当前提案寻求补充资金（146,115 美元），该资金将用于 与未承付余额一起成功继续计划运作并完成 五名学生（Avalos、Chen、Nguyen、Phan 和 Skorka）的培训过程，他们已被列入名单 eRA Commons X-Train 系统。这笔资金将用于支持5名学员的生活津贴和部分学费， 研究用品、会议旅行和研究密集型校外夏季研究经验 环境，此外还为项目人员提供部分薪资支持。目标是继续 提供更深入和具体的研究培训，以培养技术、操作和专业人才 技能，重点加强学员在现有课程和研究训练中的定量能力 以下家长奖目标中描述的活动。这5名学生即将毕业 2023 年 5 月，目前正在从事教师指导的研究项目，在这些项目中他们表现出了强大的能力 进步;此外，他们正在准备申请2022年夏季的校外研究经历。 该补充计划支持的一年培训的所有组成部分都将像母计划一样进行评估。 补充材料支持的培训计划的目标是： (i) 提供丰富、密集的培训 通过研究型荣誉课程、补充学术支持、优先获得教育经验 为学员进行注册和咨询； (ii) 在指导下提供丰富的研究经验 培养批判性思维的环境；此外，学者们将被要求参加短期的 2022年夏季在研究密集型机构的研究经历； (iii) 对 MARC 学者进行专业培训 领导力发展活动，以及 (iv) 鼓励研究生院准备。综合起来， 补充材料将有助于完成学者的培训，并奠定必要的基础 他们在高度竞争的氛围中进入并面对研究生院的严格教育。 此外，为了在当前的 MARC T34 计划结束后继续提供研究培训机会， 研究所领导（自然科学学院院长、副院长） 数学，以及当前 CSULB MARC 和 RISE 项目的项目主管）制定了战略 计划于 2021 年春季与 NIGMS 项目官员协商后制定。其中涉及提交新的 NIGMS 学生增强本科生研究培训计划 (U-RISE) (T34) 2022 年 5 月 （CSULB 基于其作为研究活跃机构的地位，有资格申请 U-RISE）。 U-RISE 领导团队已经确定，其中包括当前 T34 MARC 计划的关键人员。计划是 申请 30 个名额，用于培训来自不同背景的本科生，并提出建议的开始日期 如果有资金的话，将于 2023 年 6 月 1 日生效。学员将在两年内获得丰富的学术和研究经验 几年，这将为他们的研究生课程做好准备。他们将与教职员工一起进行研究 来自不同的背景、学科和职业阶段。同时，我们要求终止 正在进行的 RISE 计划 (04/01/2020-03/31/2025)（有 20 个资助名额）早于其预计结束日期（在 与 NIH 项目官员协商），以免与 U-RISE 重叠。这将确保连续 为 CSULB 学生提供研究培训机会。 综上所述，家长奖励的补充是完成孩子培训的关键要求。 五名 MARC 学者。预计将对他们的职业决策和研究生入学产生持久影响 生物医学领域的项目。

项目成果

SAR Matrices Enable Discovery of Mixed Efficacy μ-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore.

SAR 矩阵能够通过芳香胺药效团发现具有简化结构的混合功效 γ-阿片受体激动剂肽模拟物。

• DOI: 10.1021/acschemneuro.0c00693
• 发表时间: 2021
• 期刊: ACS chemical neuroscience
• 影响因子: 5
• 作者: Henry,Sean;Anand,JessicaP;Brinkel,AshleyC;McMillan,DouglasM;Twarozynski,JackJ;Loo,ChristianE;Traynor,JohnR;Mosberg,HenryI
• 通讯作者: Mosberg,HenryI

Synthesis and evaluation of an alkyne-modified ATP analog for enzymatic incorporation into RNA.

• DOI: 10.1016/j.bmcl.2016.02.038
• 发表时间: 2016-04-01
• 期刊: Bioorganic & medicinal chemistry letters
• 影响因子: 2.7
• 作者: Zheng Y;Beal PA
• 通讯作者: Beal PA

Calixarene-mediated liquid membrane transport of choline conjugates 3: The effect of handle variation on neurotransmitter transport.

• DOI: 10.1016/j.bmcl.2017.05.009
• 发表时间: 2017-07-01
• 期刊: Bioorganic & medicinal chemistry letters
• 影响因子: 2.7
• 作者: Collins JL 3rd;Fujii A;Roshandel S;To CA;Schramm MP
• 通讯作者: Schramm MP

Hybrid peptides as platform for synchronized combination therapy.

• DOI: 10.1016/j.colsurfb.2023.113326
• 发表时间: 2023-06
• 期刊: Colloids and surfaces. B, Biointerfaces

Identification and characterization of a novel phosphoregulatory site on cyclin-dependent kinase 5.

• DOI: 10.1016/j.bbrc.2018.09.017
• 发表时间: 2018-10-12
• 期刊: Biochemical and biophysical research communications
• 影响因子: 3.1
• 作者: Roach BL;Ngo JM;Limso C;Oloja KB;Bhandari D
• 通讯作者: Bhandari D