Beekeeper Administrative Core for COSMIIC HORNET

COSMIIC HORNET 的养蜂人管理核心

• 批准号: 10549467
• 负责人: KEVIN L. KILGORE
• 金额: $ 76.54万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-10 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10549467
• 关键词: Adoption; Apidae; Applications Grants; Area; Arrhythmia; Autonomic nervous system; Bladder; Brain; Budgets; CBL gene; California; Cardiovascular system; Cerebral Palsy; Charge; Clinic; Clinical Trials; Communication; Communities; Congestive Heart Failure; Data; Devices; Diabetes Mellitus; Disease; Documentation; Education; Electrodes; Electronics; Endocrine; Engineering; Ensure; Ethics; Family; Feedback; Foundations; Funding; Goals; Grant; Healthcare Systems; Heart Atrium; Human; Hypertension; Implant; Incontinence; Institution; Intestines; Label; Los Angeles; Macular degeneration; Marketing; Medical; Menopause; Michigan; Monitor; Motor; Myocardial Infarction; Names; Nerve Pain; Obesity; Ohio; Pain; Peripheral Nerves; Persons; Process; Property; Research; Resources; Retina; Retinitis Pigmentosa; Running; Schedule; Scientist; Sex Functioning; Skeletal Muscle; Spinal Cord; Spinal Ganglia; Spinal cord injury; Stomach; Stroke; Synapses; System; Technology; Testing; Universities; bioelectricity; bioelectronics; body system; clinical application; design; disability; first-in-human; implant design; implantable device; innovation; interest; meetings; neuroregulation; novel; online community; open source; operation; patient population; pelvic organ prolapse; recruit; relating to nervous system; spasticity; spinal cord and brain injury; web site

The primary goal of this COSMIIC HORNET project is to enable the research field to not only have access to new implantable technology, but also, where possible, to establish the ability to modify and innovate around that implantable technology. In order to achieve this goal, it is absolutely necessary that the COSMIIC HORNET project is directly applicable to the bioelectronic research community and provides the appropriate resources. To achieve this, we have formed a team of over 30 experts in neural interface technologies and their clinical applications. This “Beekeeper Team” will provide administrative oversight for the project. A key feature of our Beekeeper core is that it has broad representation of the spectrum of clinical applications for our implantable open source neuromodulation technology. The long-term objective of this project is widespread use of the COSMIIC modules to develop new medical treatments for a wide range of applications. This requires a focus on early dissemination and sustainability. The administration of this project will therefore have the following three specific aims: Aim 1) Ensure the widespread utility of the novel modules. The beekeepers will provide feedback on novel designs early in the design process to ensure that the device specifications and modes of operation will serve a wide community of users. In conjunction with an external advisory board, the administrative team will also monitor progress on the scheduled project milestones. Aim 2) Evaluate the distributed resources for completeness and safe ethical use. The COSMIIC HORNET modules will be designed for use by research teams with strong engineering expertise, who must have a thorough understanding of the devices they will use. The Beekeeper team will evaluate design and regulatory documentation prior to distribution to the public Aim 3) Create a community of early adopters who can serve as a resource for others. Each beekeeper has a personal interest in using this technology for their own research. During the course of this project, they will lay the groundwork for that use at the end of three years through FDA communications and grant applications. Each of the application represented by the beekeepers has a larger community of scientists who may benefit from using these devices. Beekeepers will serve as an ambassador for these novel devices within that community and we will also support and incorporate additional users who wish to become early adopters. At the end of this project, the existing modules already in human use will be fully open-sourced including all regulatory communications. Novel designs will be complete, and well documented. There will also be an online community of users at a variety of stages of adoption.

COSMIIC HORNET项目的主要目标是使研究领域不仅拥有