Siyakhula: Growing HIV/TB Research Knowledge for Growing Healthy Kids in Eswatini

Siyakhula：为斯威士兰的健康儿童增长艾滋病毒/结核病研究知识

• 批准号: 10671220
• 负责人: ANNA M MANDALAKAS
• 金额: $ 8.26万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-17 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10671220
• 关键词: AIDS/HIV problem; Adolescent; African; Back; Child; Child Health; Childhood; Climate; Clinical Research; Collaborations; Country; Doctor of Philosophy; Educational Curriculum; Educational process of instructing; Enrollment; Ensure; Epidemic; Funding; Goals; HIV/TB; Health; Health Professional; Human; Infant; Knowledge; Lead; Master of Public Health; Measurable; Medicine; Mentors; Monitor; Pediatrics; Population; Public Health; Public Health Schools; Research; Research Methodology; Research Personnel; Research Priority; Research Training; Resource-limited setting; Scientist; Texas; Time; Training; Training Programs; Translational Research; Tuberculosis; Universities; base; climate change; climate impact; climate-related health; cohort; collaborative approach; college; comorbidity; health training; innovation; novel; programs; skills; success; virtual

Program Summary/Abstract In collaboration with the University of Eswatini, the Eswatini Ministry of Health (including national HIV and TB programs), and Stanford Unversity, Baylor College of Medicine (BCM) will conduct training in HIV/AIDS research methods with a focus on pediatrics and Tuberculosis (TB) co-morbidity while considering the imminent threat of climate change on children's health. Other key partners include The University of Texas School of Public Health (UTHealth SPH) who will support and mentor long-term trainees during Public Health Masters and Doctoral level studies. Our existing collaborative HIV/TB training program (Siyakhula) trains i) three doctoral candidates to become Independent Investigators in clinical and translational research focusing on HIV/TB in pediatric (infants, children, adolescents) populations, and ii) two in-country cohorts of public health trainees to become Associate Investigators in child health research. The training capitalizes on a novel Eswatini-US dual mentoring strategy to ensure retention, success, and relevance of research conducted by US-based long-term Siyakhula Scholars. Long-term Siyakhula Scholars enroll in UTHealth SPH to earn a PhD or DrPH and conduct thesis activities in Eswatini engaging in-country Siyakhula Scholars and mentors. We employ a "teach-back" approach in which the long-term trainees participate in Eswatini-based training forums to develop teaching skills and strengthen partnerships with in-country scholars. Our overarching goal is to strengthen clinical research capacity in Eswatini while simultaneously producing high-quality researchers who will successfully transition to independence, obtain independent funding and lead national efforts to end the HIV/TB epidemic while now considering the impact of climate change on health. Climate change is the crisis of our time. However, training of health practitioners and tomorrow's scientists has virtually missing from the climate change agenda; particularly for child health and resource constrained setting where the impact is predicted to be greatest. Our innovative supplemental curriculum i) highlights the interconnectedness of child health and climate change, ii) seeks to train local scientists, clinicians, and public health professionals within a burgeoning African research training program, iii) supports local investigator driven research to identify climate change levers that are most impactful for Emaswati, iv) establishes monitoring of core climate metrics, and iv) promises to bring about measurable change regarding climate change as a key driver of human health in Eswatini. Our collaborative approach is driven by local research priorities ensuring integration of climate change and health within the national research strategy to provide sustainable impact.

计划摘要/摘要 与斯威士兰大学合作，斯威士兰卫生部（包括国家艾滋病毒和结核病 项目）和斯坦福大学、贝勒医学院（BCM）将开展艾滋病毒/艾滋病研究培训 重点关注儿科和结核病 (TB) 共病的方法，同时考虑到迫在眉睫的威胁 气候变化对儿童健康的影响。其他主要合作伙伴包括德克萨斯大学公共卫生学院 （UTHealth SPH）将在公共卫生硕士和博士阶段支持和指导长期学员 研究。我们现有的艾滋病毒/结核病合作培训计划 (Siyakhula) 培训 i) 三名博士候选人 成为临床和转化研究的独立研究者，重点关注儿科（婴儿、 儿童、青少年）人口，以及 ii） 两批国内公共卫生实习生将成为助理 儿童健康研究的调查人员。该培训利用了新的斯威士兰-美国双重指导策略 确保美国长期 Siyakhula 学者进行的研究的保留、成功和相关性。 长期 Siyakhula 学者入读 UTHealth SPH 以获得博士学位或 DrPH 并在以下领域开展论文活动： 斯威士兰聘请国内的 Siyakhula 学者和导师。我们采用“回授”方法，其中 长期学员参加斯威士兰的培训论坛，以发展教学技能并加强 与国内学者的合作伙伴关系。我们的首要目标是加强临床研究能力 斯威士兰同时培养高素质研究人员，他们将成功过渡到 独立，获得独立资金并领导国家努力结束艾滋病毒/结核病流行，同时 现在考虑气候变化对健康的影响。 气候变化是我们这个时代的危机。然而，对卫生从业者和未来科学家的培训已经 气候变化议程实际上被忽视了；特别是对于儿童健康和资源有限的环境 预计影响最大的地方。我们的创新补充课程 i) 强调 儿童健康与气候变化的相互关联性，ii) 寻求培训当地科学家、临床医生和公众 新兴非洲研究培训计划中的卫生专业人员，iii) 支持当地研究者驱动 旨在确定对 Emaswati 影响最大的气候变化杠杆的研究，iv) 建立监测 核心气候指标，以及 iv) 承诺带来以气候变化为关键的可衡量的变化 斯威士兰人类健康的推动者。我们的合作方法由当地研究优先事项驱动，确保 将气候变化和健康纳入国家研究战略，以提供可持续的影响。