Siyakhula: Growing HIV/TB Research Knowledge for Growing Healthy Kids in Eswatini

计划摘要/摘要 与埃斯瓦蒂尼大学合作，埃斯瓦蒂尼卫生部(包括国家艾滋病毒和结核病 计划)，以及斯坦福大学，贝勒医学院(BCM)将进行艾滋病毒/艾滋病研究培训 方法重点关注儿科和结核病(TB)的共同发病，同时考虑到 气候变化对儿童健康的影响。其他主要合作伙伴包括德克萨斯大学公共卫生学院 (UTHealth SPH)谁将在公共卫生硕士和博士水平期间支持和指导长期受训人员 学习。我们现有的合作艾滋病毒/结核病培训计划(Siyakhula)培养了一)三名博士生 成为临床和转化性研究中的独立研究员，重点是儿童(婴儿， 儿童、青少年)人口，以及二)两批国内公共卫生实习生成为助理 儿童健康研究领域的研究人员。该培训利用了一种新的埃斯瓦蒂尼-美国双重指导战略 以确保由美国长期Siyakhula学者进行的研究的保留、成功和相关性。 长期的Siyakhula学者在UTHealth SPH注册以获得博士或博士学位，并在 埃斯瓦蒂尼在国家从事锡亚库拉学者和导师。我们采用了一种“回教”的方式 长期受训人员参加以埃斯瓦蒂尼为基础的培训论坛，以发展教学技能并加强 与国内学者建立伙伴关系。我们的总体目标是加强临床研究能力 同时培养出高质量的研究人员，他们将成功过渡到 独立，获得独立资金，领导国家努力结束艾滋病毒/结核病流行，同时 现在考虑到气候变化对健康的影响。 气候变化是我们这个时代的危机。然而，对卫生从业者和未来科学家的培训已经 几乎没有列入气候变化议程；特别是在儿童健康和资源有限的情况下 据预测，那里的影响最大。我们的创新补充课程I)突出了 儿童健康与气候变化的相互关联性，ii)寻求培训当地科学家、临床医生和公众 新兴的非洲研究培训计划中的卫生专业人员，III)支持当地调查人员推动 确定对Emaswati影响最大的气候变化杠杆的研究，四)建立监测 核心气候指标，以及四)承诺带来可衡量的变化，将气候变化视为关键 埃斯瓦蒂尼的人类健康推动者。我们的协作方法是由本地研究优先事项推动的，确保 将气候变化和健康纳入国家研究战略，以产生可持续影响。

Program Summary/Abstract In collaboration with the University of Eswatini, the Eswatini Ministry of Health (including national HIV and TB programs), and Stanford Unversity, Baylor College of Medicine (BCM) will conduct training in HIV/AIDS research methods with a focus on pediatrics and Tuberculosis (TB) co-morbidity while considering the imminent threat of climate change on children's health. Other key partners include The University of Texas School of Public Health (UTHealth SPH) who will support and mentor long-term trainees during Public Health Masters and Doctoral level studies. Our existing collaborative HIV/TB training program (Siyakhula) trains i) three doctoral candidates to become Independent Investigators in clinical and translational research focusing on HIV/TB in pediatric (infants, children, adolescents) populations, and ii) two in-country cohorts of public health trainees to become Associate Investigators in child health research. The training capitalizes on a novel Eswatini-US dual mentoring strategy to ensure retention, success, and relevance of research conducted by US-based long-term Siyakhula Scholars. Long-term Siyakhula Scholars enroll in UTHealth SPH to earn a PhD or DrPH and conduct thesis activities in Eswatini engaging in-country Siyakhula Scholars and mentors. We employ a "teach-back" approach in which the long-term trainees participate in Eswatini-based training forums to develop teaching skills and strengthen partnerships with in-country scholars. Our overarching goal is to strengthen clinical research capacity in Eswatini while simultaneously producing high-quality researchers who will successfully transition to independence, obtain independent funding and lead national efforts to end the HIV/TB epidemic while now considering the impact of climate change on health. Climate change is the crisis of our time. However, training of health practitioners and tomorrow's scientists has virtually missing from the climate change agenda; particularly for child health and resource constrained setting where the impact is predicted to be greatest. Our innovative supplemental curriculum i) highlights the interconnectedness of child health and climate change, ii) seeks to train local scientists, clinicians, and public health professionals within a burgeoning African research training program, iii) supports local investigator driven research to identify climate change levers that are most impactful for Emaswati, iv) establishes monitoring of core climate metrics, and iv) promises to bring about measurable change regarding climate change as a key driver of human health in Eswatini. Our collaborative approach is driven by local research priorities ensuring integration of climate change and health within the national research strategy to provide sustainable impact.