Center for the Study of Aphasia Recovery (C-STAR)

项目总结/摘要 失语症恢复研究中心（C-STAR，P50-DC 014664）探索语言恢复 中风后的损伤我们有专业知识，使用大脑成像和行为测量来识别风险 复苏的因素。中风受气候影响，在夏季和夏季发病率都有所增加 以及在温暖的地区，如美国的“中风带”。这是第一次， 这项提案将使我们能够研究气候与1）脑损伤模式（位置和 程度），和2）中风后的行为障碍模式，在慢性和急性数据。我们 将使用现有急性（N =1500）和慢性数据集（N = 260）的存档数据检查这些问题 包括人口统计学行为学和大脑成像数据点。这些数据是在南 卡罗莱纳，被认为是“中风带”的“扣”，并可能作为未来的风向标 全球变暖我们计划的分析将为夏季的整体健康负担提供新的见解 中风，这要求我们确定在夏季观察到的额外中风是否会导致 长期损伤或与症状自发消退的较小损伤相关。我们将 进行两次档案分析来解决这些问题。

Project Summary/Abstract The Center for the Study of Aphasia Recovery (C-STAR, P50-DC014664) explores recovery from language impairments following stroke. We have expertise using brain imaging and behavioral measures to identify risk factors for recovery. Stroke is influenced by the climate, with increased incidence both in the summer months as well as in warmer regions such as the `Stroke Belt` of the United States. For the first time ever, this proposal will allow us to examine the relationship between climate and 1) patterns of brain injury (location and extent) in stroke, and 2) patterns of behavioral impairment following stroke, in both chronic and acute data. We will examine these questions using archival data from existing acute (N =1500) and chronic datasets (N = 260) that include demographic, behavioral and brain imaging data points. These data were collected in South Carolina, which is considered the ‘Buckle’ of the ‘Stroke Belt’, and which may serve as a bellwether for future global warming. Our planned analyses will provide novel insights into the overall health burden of summer strokes, which requires us to determine whether additional strokes observed in the summer months lead to long-term impairment or are associated with smaller injuries where symptoms resolve spontaneously. We will pursue two archival analyses to resolve these questions.