Biobehavioral Shared Resource

生物行为共享资源 生物行为共享资源（BBSR）的总体目标是提高可行性和成功率， Moores癌症中心（MCC）的研究人员研究了生活方式行为与癌症影响之间的联系。 干预措施以及癌症结果的生物指标，以降低癌症风险和提高存活率 在诊断出癌症之后。特别报告员提供专门知识和指导， 行为研究的MCC成员谁不一定在这些领域的专业知识，或谁有 资源有限，无法使用高质量、基于科学的方法， 整合的服务核心。BBSR提供三大类服务：（1）生物指示剂， 用于确定分子机制的行为和评估，（2）行为评估，和（3） 行为干预。生物指标评估服务包括制定生物指标评估协议， 生物标本采集和处理;制定和提供处理、储存 和/或运输样品;以及直接服务静脉切开术，样品处理，样品制备， 分析（例如，DNA提取）和分析。行为评估服务包括提供设备， 培训和数据处理，以提高体力活动和久坐数据收集的质量 行为评估;基于电话的饮食回忆和身体测量的直接服务 组成;并协助基于网络的24小时饮食回忆和饮食史问卷调查。行为 干预服务包括基于理论基础的干预设计和内容指导， 医学支持的减肥、饮食和体力活动干预; 专门针对满足研究人群和行为结果需求的干预措施; 监督和质量控制;并为使用各种新的 自我监测的技术和通信方式。因此，BBSR提供了访问 生活方式行为和生物因素评估方面的专业技术、服务和专业知识， 加强科学互动和生产力，使MCC成员能够成功地获得资金， 在同行评审的高影响力期刊上发表文章。该BBSR是由一个教师主任，联席董事， 操作人员谁是高素质的，具有必要的专业知识，在这些科学和 技术领域。此外，BBSR有一个坚实的领导和继任计划。比较 适度的投资，SR工作人员正在使MCC PI能够进行以癌症为重点的行为研究， 否则继续前进。自上次CCSG审查以来，该资源继续为科学研究做出贡献。 在许多重大赠款和项目中的努力。

BIOBEHAVIORAL SHARED RESOURCE ABSTRACT The overarching goal of the Biobehavioral Shared Resource (BBSR) is to enhance the feasibility and success of Moores Cancer Center (MCC) investigators studying the link between lifestyle behaviors and effect of interventions, as well as biological indicators of cancer outcome, to reduce cancer risk and increase survival following the diagnosis of cancer. The SR provides expertise and guidance in developing and operationalizing behavioral research for MCC members who do not necessarily have expertise in these areas, or who have limited resources to use high-quality, science-based methodology without the context and efficiency of a consolidated service core. The BBSR provides services across three categories: (1) biological indicators of behavior and assessment for determining molecular mechanisms, (2) behavioral assessment, and (3) behavioral interventions. Biological indicators assessment services include development of protocols for biospecimen collection and processing; development and provision of procedures for the processing, storing and/or shipping of samples; and direct services for phlebotomy, sample processing, preparation of samples for analysis (e.g., DNA extraction), and analysis. Behavioral assessment services include providing devices, training, and processing of data to improve the quality of data collection for physical activity and sedentary behavior assessment; direct services for telephone-based dietary recalls and measurement of body composition; and assistance with web-based 24-hour dietary recalls and diet history questionnaires. Behavioral intervention services include guidance on intervention design and content based on theoretically-grounded and empirically-supported weight loss, diet and physical activity interventions; protocol development for interventions that are specifically targeted to meet the needs of study populations and behavioral outcomes; supervision and quality control; and providing guidance and best practices for using a variety of new technologies and communication modalities for self-monitoring. Thus, the BBSR provides access to specialized technologies, services and expertise in lifestyle behavior and assessment of biological factors that enhance scientific interaction and productivity, enabling MCC members to successfully obtain funding and publications in peer-reviewed, high-impact journals. The BBSR is led by a Faculty Director, Co-Directors, and operations staff who are highly qualified, with the requisite expertise across the scope of these scientific and technical areas. Furthermore, the BBSR has a solid leadership and succession plan in place. For a relatively modest investment, SR staff are enabling cancer-focused behavioral studies by MCC PIs that could not otherwise go forward. Since the prior CCSG review, the resource has continued to contribute to scientific efforts in numerous major grants and projects.