Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse Research

指导艾滋病毒/药物滥用研究的先进移动医疗技术和机器学习

基本信息

  • 批准号:
    10668451
  • 负责人:
  • 金额:
    $ 19.13万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-11-19 至 2026-07-31
  • 项目状态:
    未结题

项目摘要

Abstract Renewal of my Midcareer Investigator Award in Patient-Oriented Research (K24) will allow me to continue my strong efforts directed toward successful original investigations and mentoring to generate research capacity in mobile technologies to improve health (mHealth). The impact of the initial K24 on my mentees has been striking. Since award of the initial K24, nearly two dozen of my mentees, 70% of whom are women or minorities, have been PI on NIH funded studies (under K, R, or Loan Repayment Program mechanisms). The impact the K24 on my own research has been substantial. Since 2014, I have been Principal Investigator (PI) on six federally funded awards: 1) one newly funded 4-year R01 from NIDA; 2) one R56 from NIDA; 3) one two-year R01 from NIDA; 4) one 4-year R01 from NIDA; 5) my K24 from NIDA; and 6) one newly funded 4-year DARPA research award. In addition, I received a William J Fulbright Foreign Scholarship to Malaysia. As my K24 evolved, so has my research focus. My overall research objective is to devote sufficient time to investigate use of next generation (“NextGen”) technologies, invisible biosensing, and machine learning in substance abuse and HIV research. My first research project, Virya, uses “digital phenotyping” with invisible biosensing and machine learning, to identify acute pain exacerbations in HIV+ individuals on opioids, a population at risk for problematic opioid use. The second reseach project uses mobile technologies to diagnose Covid-19 infection in HIV+ persons who inhale cannabis, itself a high-impact topic. Finally, the R01-funded MyTPill project compares the NextGen technology of unobtrusive ingestible biosensors that provide vivid, indisputable measures of medication ingestion. NextGen research discoveries become commercial products, but this process of introducing new discoveries into the healthcare economy remains deeply unfamiliar—yet increasingly important— to academic clinician-scientists. The objective of my Career Development Activities, therefore, involves learning how to navigate regulatory processes, FDA approvals, valuations, venture capital, contracts and intellectual property rights. Because of the growing importance of commercialization of research findings to the health and sustainability of academic careers, my overall mentoring objective of this K24 is to develop researchers who not only have the skills to conduct rigorous NextGen mHealth studies, but also to extend the mass of NIH-funded mHealth research into the healthcare economy. My mentoring approach incorporates several components that contributed to the success of my initial K24: dedicated funding for mentee’s early investigations; outstanding institutional support; several sources of referral of high-quality mentees; and renowned co- mentors who will help me establish a pipeline of mentees that have risen to that “cutting edge” where successful academic careers begin. This proposed K24 renewal, with its focus on NextGen technologies, invisible biosensing, and machine learning, is highly relevant to NIH’s mission because the lessons learned from this substance abuse and HIV research are directly applicable to the care of patients with common, intractable, and expensive conditions.
摘要

项目成果

期刊论文数量(34)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Relationships of Long-Term Smoking and Moist Snuff Consumption With a DNA Methylation Age Relevant Smoking Index: An Analysis in Buccal Cells.
长期吸烟和湿鼻烟消费与 DNA 甲基化年龄相关吸烟指数的关系:颊细胞分析。
Ingestible electronic sensors to measure instantaneous medication adherence: A narrative review.
  • DOI:
    10.1177/20552076221083119
  • 发表时间:
    2022-01
  • 期刊:
  • 影响因子:
    3.9
  • 作者:
    Chai PR;Vaz C;Goodman GR;Albrechta H;Huang H;Rosen RK;Boyer EW;Mayer KH;O'Cleirigh C
  • 通讯作者:
    O'Cleirigh C
Accuracy of Resident-Performed Point-of-Care Lung Ultrasound Examinations Versus Chest Radiography in Pneumothorax Follow-up After Tube Thoracostomy in Rwanda.
卢旺达插管胸腔造口术后气胸随访中住院医师进行的护理点肺部超声检查与胸部 X 光检查的准确性。
The Effect of Noise-Masking Earbuds (SleepBuds) on Reported Sleep Quality and Tension in Health Care Shift Workers: Prospective Single-Subject Design Study.
  • DOI:
    10.2196/28353
  • 发表时间:
    2022-03-22
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    Duggan NM;Hasdianda MA;Baker O;Jambaulikar G;Goldsmith AJ;Condella A;Azizoddin D;Landry AI;Boyer EW;Eyre AJ
  • 通讯作者:
    Eyre AJ
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Edward W Boyer其他文献

Edward W Boyer的其他文献

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{{ truncateString('Edward W Boyer', 18)}}的其他基金

Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse Research
指导艾滋病毒/药物滥用研究的先进移动医疗技术和机器学习
  • 批准号:
    10529984
  • 财政年份:
    2021
  • 资助金额:
    $ 19.13万
  • 项目类别:
Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse Research
指导艾滋病毒/药物滥用研究的先进移动医疗技术和机器学习
  • 批准号:
    10469618
  • 财政年份:
    2021
  • 资助金额:
    $ 19.13万
  • 项目类别:
MyTPill: A Novel Strategy to Monitor Antiretroviral Adherence among HIV+ Prescription Opioid Users
MyTPill:监测 HIV 处方阿片类药物使用者抗逆转录病毒依从性的新策略
  • 批准号:
    10116617
  • 财政年份:
    2019
  • 资助金额:
    $ 19.13万
  • 项目类别:
MyTPill: A Novel Strategy to Monitor Antiretroviral Adherence among HIV+ Prescription Opioid Users
MyTPill:监测 HIV 处方阿片类药物使用者抗逆转录病毒依从性的新策略
  • 批准号:
    10381648
  • 财政年份:
    2019
  • 资助金额:
    $ 19.13万
  • 项目类别:
MyTPill: A Novel Strategy to Monitor Antiretroviral Adherence among HIV+ Prescription Opioid Users
MyTPill:监测 HIV 处方阿片类药物使用者抗逆转录病毒依从性的新策略
  • 批准号:
    10550038
  • 财政年份:
    2019
  • 资助金额:
    $ 19.13万
  • 项目类别:
MyTPill: A Novel Strategy to Monitor Antiretroviral Adherence among HIV+ Prescription Opioid Users
MyTPill:监测 HIV 处方阿片类药物使用者抗逆转录病毒依从性的新策略
  • 批准号:
    10380990
  • 财政年份:
    2019
  • 资助金额:
    $ 19.13万
  • 项目类别:
Mentoring in advanced mHealth interventions for drug abuse and HAART adherence
指导针对药物滥用和 HAART 依从性的先进移动医疗干预措施
  • 批准号:
    9446608
  • 财政年份:
    2017
  • 资助金额:
    $ 19.13万
  • 项目类别:
NIDA National Early Warning System Network (iN3): An Innovative Approach
NIDA 国家预警系统网络 (iN3):创新方法
  • 批准号:
    8777695
  • 财政年份:
    2014
  • 资助金额:
    $ 19.13万
  • 项目类别:
Mentoring in advanced mHealth interventions for drug abuse and HAART adherence
指导针对药物滥用和 HAART 依从性的先进移动医疗干预措施
  • 批准号:
    8789850
  • 财政年份:
    2014
  • 资助金额:
    $ 19.13万
  • 项目类别:
Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse Research
指导艾滋病毒/药物滥用研究的先进移动医疗技术和机器学习
  • 批准号:
    10258162
  • 财政年份:
    2014
  • 资助金额:
    $ 19.13万
  • 项目类别:

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Selective actin remodeling of sensory neurons for acute pain management
感觉神经元的选择性肌动蛋白重塑用于急性疼痛管理
  • 批准号:
    10603436
  • 财政年份:
    2023
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Clinical Outcome Assessments for Acute Pain Therapeutics in Infants and young Children (COA APTIC)
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Clinical Outcome Assessments for Acute Pain Therapeutics in Infants and young Children (COA APTIC)
婴幼儿急性疼痛治疗的临床结果评估 (COA APTIC)
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    $ 19.13万
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Development of A Focused Ultrasound Device for Noninvasive, Peripheral Nerve Blockade to Manage Acute Pain
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  • 批准号:
    10740796
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    2023
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Predicting Pediatric Sickle Cell Disease Acute Pain Using Mathematical Models Based on mHealth Data
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Non-Contingent Acute Pain Stress Drives Analgesic Protection in Rats.
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    $ 19.13万
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    Alexander Graham Bell Canada Graduate Scholarships - Master's
Prefrontal Cortex Hemodynamic Responses to Mindfulness Meditation and Acute Pain
前额皮质血流动力学对正念冥想和急性疼痛的反应
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