Ultrafine Particulate Monitor for Personal Exposure Assessment

用于个人暴露评估的超细颗粒监测仪

• 批准号: 10670861
• 负责人: David Michael Woolsey
• 金额: $ 88.34万
• 依托单位: AERODYNE MICROSYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-01-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10670861
• 关键词: Acoustics; Acute; Aerosols; Air; Air Movements; Air Pollutants; Airborne Particulate Matter; Aircraft; Area; Asthma; Automobiles; Behavior; Benchmarking; Calibration; Cardiovascular Diseases; Caring; Cessation of life; Chronic; Compensation; Data; Data Set; Deposition; Detection; Development; Devices; Diameter; Disease; Electronics; Environment; Environmental Exposure; Environmental Pollutants; Epidemiologic Monitoring; Etiology; Evaluation; Exposure to; Film; Force of Gravity; Frequencies; Generations; Government; Health; Heating; Home; Humidity; Industrial Health; Laboratories; Link; Malignant neoplasm of lung; Marketing; Measurement; Measures; Mechanics; Medical; Methods; Microfluidics; Modeling; Modification; Monitor; Myocardial Infarction; Optics; Outcome; Particulate; Particulate Matter; Performance; Persons; Pharmacologic Substance; Phase; Pollution; Powder dose form; Power Plants; Public Health; Qualifying; Research; Resolution; Respiratory Disease; Sampling; Signal Transduction; Small Business Innovation Research Grant; Stream; Structure; System; Techniques; Technology; Thinness; Time; Ultrafine; Uncertainty; United States; Validation; Weight; Work; Workplace; air sampling; cost; design; epidemiology study; exhaust; extreme temperature; fine particles; improved; instrument; meter; microsystems; miniaturize; nanoparticle; operation; particle; personal exposure monitor; power consumption; premature; prototype; real time monitoring; rechargeable battery; sensor; software development; technology platform; temporal measurement; validation studies; ventilation; wood smoke

Exposure to particulate air pollutants is associated with cardiovascular disease, asthma, lung cancer, and other illnesses. In the United States the CDC estimates that asthma costs $20 billion annually in medical care, lost workdays, and early deaths. However, due to the complexity of the environmental exposure mechanisms, there remains a degree of uncertainty concerning disease etiology. Wearable and highly-sensitive particulate sensors could help further elucidate the linkages between disease and particulate exposure. In this Small Business Innovation Research Phase 2 project Aerodyne Microsystems Inc. (AMI) will investigate the feasibility of a miniaturized, battery-powered, and inexpensive sensor for real-time monitoring of exposure to airborne particulate matter (PM) from 2.5 um to ultrafine. The system employs the thermophoretic deposition of particulates from a sample air stream onto a thin-film bulk acoustic wave resonator (FBAR), and determines the PM mass deposited by measuring the frequency shift of oscillation. Incorporation of micromachined-electromechanical-system (MEMS) technologies allows unprecedented reduction in power consumption, cost, sample flow rate, and size. The research plan is to develop and experimentally demonstrate a new method for generation of air flow in the device, demonstrate sensor operation across a wide range of harsh, real-world operating conditions, and realize a new technique for aerosol sampling and handling that improves the sensor level of detection. The successful outcome of the project would culminate in a low-cost analytical instrument that provides real-time mass concentration of particles in a compact, wearable form factor. The monitor would be suitable for quantification of personal exposure to a range of environmental pollutants such as automotive exhaust, wood smoke, and nanoparticles. Other markets for the instrument include ventilation control, industrial hygiene, power plant monitoring, pharmaceutical powder processing, monitoring in aircraft and automobiles, and consumer air quality monitoring.

接触空气颗粒污染物与心血管疾病、哮喘、肺癌和其他疾病有关 疾病。在美国，疾病预防控制中心估计哮喘每年花费 200 亿美元的医疗费用，损失 工作日和早逝。然而，由于环境暴露机制的复杂性， 疾病病因学仍存在一定程度的不确定性。耐磨且高度敏感的颗粒物 传感器可以帮助进一步阐明疾病和颗粒物暴露之间的联系。 在这个小型企业创新研究第二阶段项目中，Aerodyne Microsystems Inc. (AMI) 将进行调查 用于实时监测暴露的小型化、电池供电且廉价的传感器的可行性 空气中颗粒物 (PM) 从 2.5 微米到超细颗粒物。该系统采用热泳 将样本气流中的颗粒沉积到薄膜体声波谐振器 (FBAR) 上，以及 通过测量振荡的频移来确定沉积的颗粒物质量。纳入 微机械机电系统 (MEMS) 技术可实现前所未有的功耗降低 消耗、成本、样品流速和尺寸。 该研究计划是开发并实验演示一种在空气中产生气流的新方法 设备，演示传感器在各种恶劣的真实操作条件下的操作，以及 实现气溶胶采样和处理的新技术，提高传感器的检测水平。这 该项目的成功成果将最终产生一种低成本分析仪器，可提供实时数据 颗粒质量集中在紧凑、耐磨的外形中。该显示器适用于 量化个人接触一系列环境污染物的情况，例如汽车尾气、木材 烟雾和纳米粒子。该仪器的其他市场包括通风控制、工业卫生、 发电厂监控、医药粉末加工、飞机和汽车监控以及 消费者空气质量监测。