Ultrafine Particulate Monitor for Personal Exposure Assessment

暴露在颗粒性空气污染物中与心血管疾病、哮喘、肺癌和其他疾病有关 疾病。美国疾病控制与预防中心估计，哮喘每年的医疗费用为200亿美元， 工作日和早逝。然而，由于环境暴露机制的复杂性， 关于疾病病因仍然存在一定程度的不确定性。可穿戴且高度敏感的颗粒物 传感器可以帮助进一步阐明疾病和颗粒物暴露之间的联系。 在小企业创新研究第二阶段项目中，Aerodyne MicroSystems Inc.(AMI)正在调查 小型化、电池供电和廉价的传感器用于实时监测暴露的可行性 空气中的颗粒物(PM)从2.5微米到超细。该系统采用了热电泳法 将样品气流中的颗粒沉积到薄膜体声波谐振器(FBAR)上 通过测量振荡的频移来确定沉积的PM质量。成立为法团 微机械-机电系统(MEMS)技术可实现前所未有的功率降低 消耗、成本、样品流速和大小。该项目的成功结果最终将是 低成本分析仪器，以紧凑、可穿戴的形式提供实时颗粒质量浓度 外形尺寸。 这一多样性补充中涵盖的研究计划将指导AMI的工作，以实现原型商业 能够进行气溶胶尺寸分级的监视器。该项目将进一步扩展Mohammadreza(Reza)Khani的项目， 该项目的补充，计算流体动力学(CFD)模拟方面的经验 设备的发展关系到人类的健康。本项目中描述的职业发展计划将促进 Reza在许多领域的增长与成为小企业中的领先企业家有关。

Exposure to particulate air pollutants is associated with cardiovascular disease, asthma, lung cancer, and other illnesses. In the United States the CDC estimates that asthma costs $20 billion annually in medical care, lost workdays, and early deaths. However, due to the complexity of the environmental exposure mechanisms, there remains a degree of uncertainty concerning disease etiology. Wearable and highly-sensitive particulate sensors could help further elucidate the linkages between disease and particulate exposure. In the Small Business Innovation Research Phase 2 project, Aerodyne Microsystems Inc. (AMI) is investigating the feasibility of a miniaturized, battery-powered, and inexpensive sensor for real-time monitoring of exposure to airborne particulate matter (PM) from 2.5 um to ultrafine. The system employs the thermophoretic deposition of particulates from a sample air stream onto a thin-film bulk acoustic wave resonator (FBAR) and determines the PM mass deposited by measuring the frequency shift of oscillation. Incorporation of micromachined-electromechanical-system (MEMS) technologies allows unprecedented reduction in power consumption, cost, sample flow rate, and size. The successful outcome of the project would culminate in a low-cost analytical instrument that provides real-time mass concentration of particles in a compact, wearable form factor. The research plan covered in this diversity supplement will guide AMI’s work towards a prototype commercial monitor capable of aerosol size fractionization. The project will further extend Mohammadreza (Reza) Khani’s, the project supplementee, experience in computational fluid dynamics (CFD) simulations geared towards device development related to human health. The career development plan described in this project will foster Reza’s growth in many areas related to becoming a leading entrepreneur in small businesses.