Ultrafine Particulate Monitor for Personal Exposure Assessment

用于个人暴露评估的超细颗粒监测仪

• 批准号: 10852019
• 负责人: David Michael Woolsey
• 金额: $ 11.02万
• 依托单位: AERODYNE MICROSYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-01-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10852019
• 关键词: Acoustics; Aerosols; Air; Air Pollutants; Airborne Particulate Matter; Area; Asthma; Businesses; Cardiovascular Diseases; Caring; Cessation of life; Data; Deposition; Development Plans; Device or Instrument Development; Disease; Environment; Environmental Exposure; Epidemiologic Monitoring; Etiology; Exposure to; Film; Fostering; Frequencies; Growth; Health; Home; Human; Liquid substance; Malignant neoplasm of lung; Measurement; Measures; Medical; Monitor; Outcome; Particulate; Particulate Matter; Phase; Pollution; Public Health; Research; Sampling; Small Business Innovation Research Grant; Stream; System; Technology; Thinness; Time; Ultrafine; Uncertainty; United States; Work; Workplace; air sampling; career development; commercial prototype; cost; epidemiology study; experience; instrument; microsystems; miniaturize; particle; personal exposure monitor; power consumption; real time monitoring; sensor; simulation; technology platform

Exposure to particulate air pollutants is associated with cardiovascular disease, asthma, lung cancer, and other illnesses. In the United States the CDC estimates that asthma costs $20 billion annually in medical care, lost workdays, and early deaths. However, due to the complexity of the environmental exposure mechanisms, there remains a degree of uncertainty concerning disease etiology. Wearable and highly-sensitive particulate sensors could help further elucidate the linkages between disease and particulate exposure. In the Small Business Innovation Research Phase 2 project, Aerodyne Microsystems Inc. (AMI) is investigating the feasibility of a miniaturized, battery-powered, and inexpensive sensor for real-time monitoring of exposure to airborne particulate matter (PM) from 2.5 um to ultrafine. The system employs the thermophoretic deposition of particulates from a sample air stream onto a thin-film bulk acoustic wave resonator (FBAR) and determines the PM mass deposited by measuring the frequency shift of oscillation. Incorporation of micromachined-electromechanical-system (MEMS) technologies allows unprecedented reduction in power consumption, cost, sample flow rate, and size. The successful outcome of the project would culminate in a low-cost analytical instrument that provides real-time mass concentration of particles in a compact, wearable form factor. The research plan covered in this diversity supplement will guide AMI’s work towards a prototype commercial monitor capable of aerosol size fractionization. The project will further extend Mohammadreza (Reza) Khani’s, the project supplementee, experience in computational fluid dynamics (CFD) simulations geared towards device development related to human health. The career development plan described in this project will foster Reza’s growth in many areas related to becoming a leading entrepreneur in small businesses.

接触空气微粒污染物与心血管疾病、哮喘、肺癌和其他疾病有关