Developing and testing the Opioid Rapid Response System

开发和测试阿片类药物快速反应系统

• 批准号: 10696992
• 负责人: Hye Jeong Choi
• 金额: $ 85.88万
• 依托单位: REAL PREVENTION, LLC
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10696992
• 关键词: Address; Behavioral; Behavioral Model; Cardiac; Cessation of life; Communication; Communities; Community Networks; County; Data; Dedications; Development; Effectiveness of Interventions; Electronic Mail; Emergency Situation; Emergency response; Event; Evidence based program; Expenditure; Focus Groups; Goals; Health; Health Personnel; Health Promotion; Indiana; Individual; Innovation Corps; Interview; Knowledge; Life; Link; Literature; Marketing; Medical; Medical emergency; Modeling; Multimedia; Naloxone; Naloxone Training; Nature; Online Systems; Opioid; Overdose; Overdose reversal; Participant; Performance; Persons; Phase; Pilot Projects; Prevention; Procedures; Protocols documentation; Public Health; Reaction Time; Readiness; Recovery; Research; Resources; Rural; Sampling; Science; Small Business Innovation Research Grant; Societies; Standardization; Stroke; Suicide; System; Technology; Testing; Training; Training Programs; Urban Community; Work; base; behavior change; behavioral outcome; commercialization; commune; communication theory; comparative efficacy; cost; cost effective; design; digital; digital intervention; dissemination strategy; effectiveness evaluation; emergency service responder; evidence base; implementation science; improved; innovation; innovative technologies; lens; multimodality; opioid epidemic; opioid mortality; opioid overdose; prototype; psychological outcomes; randomized trial; randomized, clinical trials; recruit; response; rural area; social cognitive theory; social group; social influence; social media; social stigma; theories; urban setting; usability; web site

Abstract This Phase II SBIR will develop and demonstrate the efficacy of the Opioid Rapid Response System (ORRS) to improve responses to opioid overdoses. Opioid overdoses exact a tremendous cost in lives and expenditures. Naloxone has been developed to counteract overdoses; however, the nature of these events requires a rapid response, a situation that challenges emergency responders in both lightly populated rural areas as well as densely populated urban communities. Apps now exist with the potential to obviate timing concerns by linking lay citizen responders to events through the 911 system. One such app, PulsePoint, is already in place in 4,100 communities throughout the U.S. for cardiac events, while two other potential partners, OpiSafe and Brave, focus on overdoses and have expanding customer bases. Other communities simply distribute naloxone as widely as possible. Neither naloxone distribution nor the apps can accomplish their goals without effectively recruiting and training many citizen responders who are both able to administer life-saving naloxone and confident in their ability to do so. To date, there are no evidence-based programs to accomplish these goals. This project is designed to develop innovative and effective recruitment and training strategies to fill this gap. ORRS was based on a pilot project demonstrating that lay citizen responders could utilize the PulsePoint app to respond to overdose events. In Phase I, we developed an effective recruitment protocol based on identity theory that uses appeals to individuals (personal identity appeals) and others (communal appeals) and administered it through multi-modalities. We also developed a prototype of ORRS online training and demonstrated usability and feasibility through a study in five Indiana counties. In Phase II, ORRS recruitment will be refined to improve the performance of the social media component, the training platform will be enhanced to focus on CPR and stigma reduction as well as enhanced engagement, and a national RCT will be conducted in 8 communities. Recruitment and training effects on psychological and behavioral outcomes will be evaluated. The project has great promise for rapid and wide dissemination through the PulsePoint, OpiSafe, and Brave Technology Coop networks of communities as well as public health departments. The project has the potential to develop a model for community responses to similar public health events.

抽象的 该 II 期 SBIR 将开发并证明阿片类药物快速反应系统 (ORRS) 的功效 改善对阿片类药物过量的反应。阿片类药物过量服用会造成巨大的生命和支出损失。 纳洛酮的开发是为了对抗药物过量；然而，这些事件的性质需要迅速 这种情况对人口稀少的农村地区以及人口稀少的应急响应人员提出了挑战 人口稠密的城市社区。现在的应用程序有可能通过链接来消除时间问题 普通公民通过 911 系统应对事件。 PulsePoint 就是这样一款应用程序，已在 4,100 个国家安装 美国各地的社区关注心脏事件，而另外两个潜在合作伙伴 OpiSafe 和 Brave 关注过量用药并扩大客户群。其他社区只是将纳洛酮分配为 尽可能广泛。如果没有有效的解决方案，纳洛酮发行版和应用程序都无法实现其目标 招募和培训许多公民响应者，他们既能够管理挽救生命的纳洛酮， 对他们这样做的能力充满信心。迄今为止，还没有基于证据的计划来实现这些目标。 该项目旨在制定创新且有效的招聘和培训策略来填补这一空白。 ORRS 基于一个试点项目，该项目证明非专业公民响应者可以利用 PulsePoint 应用程序 应对过量事件。在第一阶段，我们开发了基于身份理论的有效招聘协议 使用对个人（个人身份诉求）和其他人（公共诉求）的诉求并进行管理 通过多种方式。我们还开发了 ORRS 在线培训原型并演示了可用性 通过对印第安纳州五个县的研究进行可行性研究。在第二阶段，ORRS 招募将被细化为 提高社交媒体部分的绩效，将增强培训平台，重点关注 心肺复苏和减少耻辱以及加强参与，并将在 8 年进行全国随机对照试验 社区。将评估招募和培训对心理和行为结果的影响。 该项目有望通过 PulsePoint、OpiSafe 和 Brave 快速广泛传播 社区和公共卫生部门的技术合作网络。该项目有潜力 开发社区应对类似公共卫生事件的模型。