Hematology Central Coordinating Center (HCCC) for the NIDDK Hematology Centers Program

NIDDK 血液学中心计划的血液学中央协调中心 (HCCC)

• 批准号: 10673068
• 负责人: John Dearborn Phillips
• 金额: $ 100万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10673068
• 关键词: Acceleration; Advisory Committees; Applications Grants; Area; Award; Cell Line; Collaborations; Communication; Communication Methods; Communication Tools; Communities; Complex; Continuing Education; Data; Data Analyses; Education; Education and Outreach; Educational Materials; Educational workshop; Electronic Mail; Ensure; Evaluation; Facebook; Funding; Funding Opportunities; Goals; Grant; Hematological Disease; Hematology; Hematopoiesis; Individual; Information Distribution; Infrastructure; Instagram; International; Laboratories; Leadership; Logistics; Modeling; National Institute of Diabetes and Digestive and Kidney Diseases; Newsletter; Non-Malignant; Pamphlets; Process; Progress Reports; Protocols documentation; Reagent; Reproducibility; Research; Research Personnel; Research Proposals; Resources; Science; Senior Scientist; Site; Slide; Standardization; Technology; Telephone; Time; Twitter; Universities; Utah; base; combat; data sharing; experience; improved; innovation; interest; meetings; novel strategies; outreach; outreach program; posters; programs; recruit; skills training; social media; success; symposium; tool; ward; web site; webinar

HCCC Project Summary: The proposed Hematology Central Coordinating Center (HCCC) will take advantage of our broad base expertise of established hematology researchers to set up a centralized site for investigators to find NIDDK- sponsored Collaborative Center of Excellence in Hematology (CCEH) Core Technology resources, Pilot & Feasibility funding opportunities, educational materials, standardized protocols and connect with other investigators. The goals of the collaborative center are to provide the tools for individual CCEHs to expand their influence by providing standardized protocols to improve reproducibility, a platform for data sharing, collaborative connections and administering a robust Pilot and Feasibility (P&F) program that is available to laboratories nationwide. We will provide timely announcements regarding information/education opportunities offered at each of the CCEHs. We aim to increase exposure of the resources available at CCEHs to recruit additional researchers to the nonmalignant hematology field. The HCCC will provide multipronged communication approaches (website, social media, newsletter, email, webinars, YouTube videos) to improve the visibility of the state-of-the-art technologies available at CCEHs. We will expand on the success of our established Collaborative P&F program. Applications will be solicited, reviewed and awarded in a time sensitive manner. This improved P&F program will increase grant applications and leverage more funding dollars for hematology research. The HCCC Education and Outreach program will use novel approaches such as “Meet the Expert” webinars to provide a real-time exchange of information and ideas that promotes innovative solutions to important questions that will rapidly advance this science. The HCCC will also provide materials; posters, brochures, handouts and general slide sets to CCEHs and NIDDK program staff to advertise these programs at national meetings. The overarching goal of these programs is to support and expand the national research effort to combat nonmalignant hematologic diseases and focus areas of hematopoiesis.

HCCC项目摘要： 拟议的血液学中央协调中心（HCCC）将利用我们的广泛基础 既定血液学研究人员的专业知识，以建立一个集中式地点，以供研究人员找到NIDDK- 赞助了血液学卓越合作中心（CCEH）核心技术资源，飞行员和 可行性资金机会，教育材料，标准化协议，并与其他 调查人员。协作中心的目标是为单个CCEHS扩展的工具提供工具 通过提供标准化协议来提高可重复性，这是数据共享的平台， 协作连接并管理可行的强大飞行员和可行性（P＆F）计划 全国实验室。我们将及时发布有关信息/教育机会的公告 在每个CCEHS上提供。我们旨在增加CCEHS可用资源的曝光率 非恶性血液学领域的其他研究人员。 HCCC将提供多收益 沟通方法（网站，社交媒体，新闻通讯，电子邮件，网络研讨会，YouTube视频）以改进 CCEHS可用的最先进技术的可见性。我们将扩大我们的成功 建立的协作行合行合计划。申请将在一段时间内巩固，审查和授予 敏感的方式。这种改进的损益计划将增加赠款申请并利用更多资金 血液学研究的美元。 HCCC教育和外展计划将使用此类新方法 作为“认识专家”网络研讨会，提供了促进信息和想法的实时交流 针对将迅速推进这项科学的重要问题的创新解决方案。 HCCC也将提供 材料;海报，小册子，讲义和一般幻灯片设置为CCEHS和NIDDK计划人员 在国家会议上宣传这些计划。这些程序的总体目标是支持和 扩大国家研究工作，以打击非恶性血液学疾病和重点领域 造血。

项目成果

Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging.

• DOI: 10.1038/s41592-022-01673-2
• 发表时间: 2022-12
• 期刊: NATURE METHODS
• 影响因子: 48
• 作者: Haase, Christa;Gustafsson, Karin;Mei, Shenglin;Yeh, Shu-Chi;Richter, Dmitry;Milosevic, Jelena;Turcotte, Raphael;Kharchenko, Peter, V;Sykes, David B.;Scadden, David T.;Lin, Charles P.
• 通讯作者: Lin, Charles P.

Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq.

• DOI: 10.1016/j.xpro.2022.101823
• 发表时间: 2022-12-16
• 期刊: STAR PROTOCOLS
• 作者: Biancon, Giulia;Busarello, Emma;Joshi, Poorval;Lesch, Bluma J.;Halene, Stephanie;Tebaldi, Toma
• 通讯作者: Tebaldi, Toma