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Enhancing experimental rigor through education in evidence synthesis

通过证据综合教育提高实验严谨性

基本信息

批准号：
10673907
负责人：
Jordan Randall Covvey
金额：
$ 9.17万
依托单位：
DUQUESNE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-01 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10673907
关键词：
Active Learning Address Area Basic Science Brain Clinical Research Clinical Sciences Communities Concept Review Data Databases Development Disease Education Educational Curriculum Elements Equity Evaluation Evaluation Studies Evidence based practice Failure Feedback Goals Grant Health Human Individual Investigation Investments Knowledge Learning Module Licensing Literature Manuscripts Methodology Methods Mind Mission National Institute of Neurological Disorders and Stroke Nervous System Patients Persons Process Proliferating Protocols documentation Public Health Publishing Recording of previous events Reporting Research Research Design Research Personnel Research Proposals Resources Review Literature Risk Science Scientist Self Efficacy Series Source Structure Techniques Text Time Training Universities Work advanced system base design digital education resources experience improved inquiry-based learning interest learning engagement learning outcome member nervous system disorder novel open data peer pre-clinical prevent response skills syntax systematic review text searching tool translational pipeline undergraduate student wasting

项目摘要

PROJECT SUMMARY/ABSTRACT More research is being published now than any other time in history and that research is accessible worldwide. Due to the rapid proliferation of research, it can be difficult if not impossible for an individual to stay abreast of important findings which can impact research and evidence-based practice. Yet, having a comprehensive understanding of the literature is foundational to advancing knowledge. This allows a researcher to identify existing gaps in knowledge so that they can design new research to advance the area forward. One way to achieve this is through a rigorous evidence synthesis, or a systematic approach to gathering and analyzing results from multiple sources. In practice, the use of evidence syntheses requires improvement, as they are often poorly conducted and reported, which has serious downstream impacts on public health. While there are ample resources currently available to researchers on the topic, they are underutilized and may not be fully accessible to all individuals who may benefit from them. The National Institute of Neurological Disorders and Stroke (NINDS) seeks to improve fundamental knowledge through timely dissemination of scientific discoveries in the area of neurological disease. This mission, across the translational spectrum, is fully supported by enhancing skills in evidence synthesis, which can prevent waste in research investment. As knowledge of the brain and nervous system advances rapidly, scientists in this area have to be highly reflexive to changing current knowledge to ensure that their work is relevant. Training in the skills of evidence synthesis enables this. Accordingly, the aim of this proposal is to develop, evaluate, and disseminate a series of educational modules on rigorous approaches to science focused on evidence synthesis. The proposed modules will cover (1) an introduction to evidence synthesis, (2) developing a research question and proposal, (3) designing literature searches, (4) conducting an evidence synthesis, (5) analyzing data from an evidence synthesis, and (6) reporting results from an evidence synthesis. The modules will be designed to be utilized by different levels of learners (introductory, intermediate, and advanced) and apply across the translational spectrum (basic science, clinical science, and public health). Module development, evaluation, and dissemination will occur with an iterative process of review and feedback across multiple stakeholders (experts and lay persons alike) to create a useful and comprehensive final product. The opportunity to improve the use of evidence synthesis techniques through a platform that is accessible to all interested scientists has significant potential to enhance scientific rigor, and ultimately, improve public health.

项目摘要/摘要现在发表的研究比历史上任何时候都多，而且全世界都可以访问这些研究。由于研究的迅速扩散，对个人来说，即使不是不可能，也很难跟上时代的潮流可能影响研究和循证实践的重要发现。然而，拥有一个全面的对文献的理解是推进知识进步的基础。这使得研究人员能够识别现有的知识差距，以便他们能够设计新的研究来推动该领域的发展。一种方法要做到这一点，可以通过严格的证据合成，或系统的方法来收集和分析结果来自多个来源。在实践中，证据合成的使用需要改进，因为它们经常管理和报告不力，这对公众健康产生了严重的下游影响。虽然有足够的资金目前可供研究人员使用的资源，这些资源未得到充分利用，可能无法完全获取所有可能从中受益的个人。国家神经疾病和中风研究所(NINDS)致力于提高基础知识通过及时传播神经疾病领域的科学发现。这项任务，跨越翻译光谱，得到了证据合成技能的全面支持，这可以防止浪费在研究投资方面。随着对大脑和神经系统的了解迅速发展，这一领域的科学家必须高度反应地改变当前的知识，以确保他们的工作是相关的。培训中的证据合成的技巧使这一点成为可能。因此，本提案的目的是开发、评估和传播一系列教育模块关于科学的严格方法，侧重于证据合成。建议的单元将包括(1)和证据合成导论，(2)提出研究问题和建议，(3)设计文献搜索，(4)进行证据合成，(5)分析来自证据合成的数据，以及(6)报告证据合成的结果。这些模块将被设计成供不同水平的学习者使用 (入门、中级和高级)，并在翻译范围(基础科学、临床)中应用科学和公共卫生)。模块的开发、评估和传播将通过迭代进行在多个利益相关者(专家和非专业人员)之间进行审查和反馈的过程，以创建有用的和全面的最终产品。有机会通过所有人都能接触到的平台改进证据合成技术的使用感兴趣的科学家在提高科学严谨性和最终改善公共健康方面具有巨大的潜力。