Learning Health System training program: PROgRESS--Patient/ pRactice Outcomes and Research in Effectiveness and Systems Science

项目摘要 在相关临床证据的生成、经证实的临床应用的广泛实施方面存在重大差距 将干预措施付诸实践，并制定知情的政策。设计了学习型医疗保健系统 “为每位患者和提供者的协作医疗保健选择生成并应用最佳证据， 推动发现过程，将其作为患者护理的自然结果，并确保创新、质量、安全， 和医疗保健的价值。” 范德比尔特致力于培养一支经过正式培训、精通最佳 整合科学发现、证据实施、信息和评估的方法 学习型医疗保健系统中的健康政策。我们建议建立范德比尔特病人， 有效性和系统科学的实践成果和研究（PROgRESS）计划， 交叉培训博士后研究人员与学习医疗保健系统的重点在三个核心学科： 1)以患者为中心的结果研究-确定哪些策略对患者最有效; 2） 实施科学-实施和评估这些有效的战略付诸实践;以及，3）健康 政策/社区健康-影响政策，使所有患者受益，并改善社区的健康。 通过交叉培训这些领域的研究人员，我们将吸引不同领域的学员和导师 学科和模型团队科学;我们将提供榜样和论坛，展示知识分子 跨学科研究在促进人类健康方面的生产力和实际效益;我们将 认可团队方法，以填补知识空白并将知识转化为应用。一个多样化 通过临床/研究奖学金，一个蓬勃发展的实施科学， 计划，一个定位良好的卫生政策部，并在包括梅哈里医学院的合作伙伴。 PROgRESS学员将有机会获得良好的教师导师与持续的联邦资金， 指导早期职业培训生的广泛记录。每个学员的奖学金监督委员会 (SOC)将从以患者为中心的成果研究中经验丰富的导师中汲取经验， 执行科学和卫生政策/社区卫生。该计划将有3个培训部分 进行了2年以上：1）先进的教学法，包括学位课程或重点课堂作业; 2）正式 导师制，为学员学习卫生系统科学的K级培训做好准备;以及3）体验式 通过开展研究项目进行学习。学员将得到各种机构的支持， 培训和发展资源，包括：正在进行的卫生服务工作;临床质量和 实施研究学术系列，期刊俱乐部，生物统计学研讨会，临床和翻译 研讨会和同行指导活动。综合起来，这些资源为以下方面提供了最佳环境： 培养下一代学习健康系统研究人员。

PROJECT SUMMARY Major gaps exist in the generation of relevant clinical evidence, widespread implementation of proven clinical interventions into practice, and formulation of informed policies. The learning healthcare system is designed to “generate and apply the best evidence for the collaborative healthcare choices of each patient and provider, drive the process of discovery as a natural outgrowth of patient care, and ensure innovation, quality, safety, and value in healthcare.” Vanderbilt is committed to develop a cadre of investigators who are formally trained and well versed in best methods for integrating scientific discovery, evidence implementation, and information and evaluation of health policies within the learning healthcare system. We propose to establish the Vanderbilt Patient, pRactice Outcomes and Research in Effectiveness and Systems Science (PROgRESS) Program to cross train post-doctoral investigators with the focus of the learning healthcare system in three core disciplines: 1) Patient Centered Outcomes Research -To determine which strategies are most effective for patients; 2) Implementation Science-To implement and evaluate those effective strategies into practice; and, 3) Health Policy/ Community Health-To influence policy to benefit all patients and improve health of the community. By cross training researchers in these areas we will draw together groups of trainees and mentors across disciplines and model team science; we will provide role models and forums that demonstrate the intellectual productivity and practical benefits of interdisciplinary research in advancing human health; and we will endorse team approaches to filling gaps in knowledge and translating knowledge into application. A diverse pool of talented applicants is available through clinical/research fellowships, a thriving Implementation Science program, a well-positioned Department of Health Policy, and in partners including Meharry Medical College. PROgRESS trainees will have access to well-established faculty mentors with sustained federal funding and an extensive track record of mentoring early career trainees. Each trainee's Scholarship Oversight Committee (SOC) will draw from an experienced pool of mentors in Patient Centered Outcomes Research, Implementation Science and Health Policy/Community Health. The program will have 3 training components conducted over 2 years: 1) advanced didactics, including degree program or focused classwork; 2) formal mentorship that prepares trainees for K level training in Learning Health Systems science; and 3) experiential learning through the conduct of a research project. Trainees will be supported by a broad array of institutional resources for training and development, including: Health Services Works in Progress; Clinical Quality and Implementation Research scholarly series, journal clubs, Biostatistics Seminars, clinical and translational seminars, and peer-mentoring activities. Taken together, these resources provide an optimal environment for developing the next generation of Learning Health System researchers.