Mayo Clinic Center for Clinical and Translational Science (CCaTS)

梅奥诊所临床和转化科学中心 (CCaTS)

• 批准号: 10674614
• 负责人: VESNA D GAROVIC
• 金额: $ 793.42万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-18 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10674614
• 关键词: Acceleration; Address; Advocate; COVID-19; COVID-19 pandemic; Caring; Classification; Clinic; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Competence; Country; Education; Elements; Environment; Event; Faculty; Funding; Goals; Health; Health system; Healthcare; Human; Incubators; Individual; Informatics; Institution; Interdisciplinary Study; Investments; Justice; Knowledge; Leadership; Learning; Medical Students; Methodology; Methods; Minnesota; Mission; National Center for Advancing Translational Sciences; Patient Care; Patients; Persons; Population; Positioning Attribute; Postdoctoral Fellow; Process; Research; Research Personnel; Resources; Role; Rural Population; Scientist; Secure; Structural Racism; Talents; Technology; Training; Training and Education; Translational Research; Translations; Trust; United States National Institutes of Health; Vision; Work; base; clinical center; clinical practice; community engagement; digital; digital health; equity, diversity, and inclusion; graduate student; health care service organization; health disparity; health equity; health equity promotion; health inequalities; improved; innovation; interest; medical schools; member; multidisciplinary; novel; operation; pandemic disease; programs; response; social disparities; synergism; theories; tool; underserved community

Contact PD/PI: Lucchinetti, Claudia F. OVERALL: Project Summary/Abstract Mayo Clinic is one of the largest not‐for‐profit, academic health systems, top-ranked for quality more often than any other health care organization. It has integrated operations in 5 U.S. states, and more than 1 million people came to Mayo Clinic for care last year. Clinical and translational science (CTS) is a fundamental and highly valued element of Mayo Clinic; indeed, all research at Mayo Clinic is directed towards translation of scientific knowledge to improve patient care, with almost 60% of our NIH funding base classified as clinical research or trials. In recognition of the importance of continued advances in CTS to the Mayo Clinic mission, our institutional leadership has entrusted the Mayo Clinic Center for Clinical and Translational Sciences (CCaTS) to be the engine of translational innovation and the institutional advocate for CTS and translational research. CCaTS has served as a CTS innovation incubator for numerous efforts that were created with CCaTS funding and are now supported by the institution. The overall vision of CCaTS is to enable high-quality, team-based multidisciplinary research that accelerates clinical trial innovation, facilitates digital health transformation, and partners with our stakeholders and communities to improve patient care and health for all people. Our team- based culture has been described as one of “boundarylessness,” wherein organizational barriers are removed to enable talent, innovation, and knowledge to converge where needed. In this context and that of our longstanding commitment to patient-focused research, we are uniquely positioned to accomplish the following Specific Aims. In Aim 1, we will simplify and accelerate the work of translation to improve health for all by advancing clinical trial innovations and digital health transformations, streamlining methods and processes, and developing novel informatics solutions that increase efficiency and drive implementation of discoveries that improve health and promote health equity. In Aim 2, we will enhance our education programs through the expanded reach of competency-based, learner-focused solutions, training a diverse, inclusive, multidisciplinary CTS workforce to be prepared to address the urgent health care needs of all communities in a rapidly changing environment. In Aim 3, we will engage local community members and patients to be active partners in translational teams, expanding research capabilities of underserved communities, including rural populations. Our goal is to improve health and reduce health inequities by helping these communities realize the benefits of CTS. In Aim 4, we will expand national and regional partnerships and strengthen collaborative CTS networks in all aspects of CTS and education, focusing on sharing innovative approaches and prioritizing diversity, equity, and inclusion, with the goal of improving human health and advancing health equity. In summary, sustained investment in CCaTS will enable us to continue to meet ongoing and emergent challenges in health care for all, as exemplified by our response to support communities through the COVID-19 crisis. Project Summary/Abstract Page 289 Contact PD/PI: Lucchinetti, Claudia F.

联系PD/PI: Lucchinetti， Claudia F。

项目成果

Association Between Antifibrinolytic Therapy and Perioperative Outcomes in Patients With Coronary Artery Stents Undergoing Noncardiac Surgery.

• DOI: 10.1213/ane.0000000000005522
• 发表时间: 2021-06-01
• 期刊: Anesthesia and analgesia
• 影响因子: 5.7
• 作者: Boswell MR;Smith MM;Frank RD;Brown MJ;Abcejo AS;Kor TM;Gulati R;Smith BB
• 通讯作者: Smith BB

Machine Learning Identifies Smartwatch-Based Physiological Biomarker for Predicting Disruptive Behavior in Children: A Feasibility Study.

• DOI: 10.1089/cap.2023.0038
• 发表时间: 2023-11
• 期刊: Journal of child and adolescent psychopharmacology
• 影响因子: 1.9

Childhood psychiatric outcomes in the context of suspected neglect and abuse reports related and unrelated to parental substance use.

• DOI: 10.1016/j.chiabu.2021.105344
• 发表时间: 2021-12
• 期刊: Child abuse & neglect
• 影响因子: 4.8
• 作者: Gandhi KD;Romanowicz M;Croarkin PE;Thapa P;Limbeck M;Desai J;Benarroch AJM;Shekunov J
• 通讯作者: Shekunov J

The comparative effectiveness of decision aids in diverse populations with early stage prostate cancer: a study protocol for a cluster-randomized controlled trial in the NCI Community Oncology Research Program (NCORP), Alliance A191402CD.

• DOI: 10.1186/s12885-018-4672-3
• 发表时间: 2018-08-06
• 期刊: BMC cancer
• 影响因子: 3.8
• 作者: Pacyna JE;Kim S;Yost K;Sedlacek H;Petereit D;Kaur J;Rapkin B;Grubb R;Paskett E;Chang GJ;Sloan J;Basch E;Major B;Novotny P;Taylor J;Buckner J;Parsons JK;Morris M;Tilburt JC
• 通讯作者: Tilburt JC

Topics and Sentiment Surrounding Vaping on Twitter and Reddit During the 2019 e-Cigarette and Vaping Use-Associated Lung Injury Outbreak: Comparative Study.

• DOI: 10.2196/39460
• 发表时间: 2022-12-13
• 期刊: JOURNAL OF MEDICAL INTERNET RESEARCH
• 影响因子: 7.4
• 作者: Wu, Dezhi;Kasson, Erin;Singh, Avineet Kumar;Ren, Yang;Kaiser, Nina;Huang, Ming;Cavazos-Rehg, Patricia A.
• 通讯作者: Cavazos-Rehg, Patricia A.