NEUROIMAGING CORE

神经影像核心

基本信息

批准号：
10677602
负责人：
Peter CM Van Zijl
金额：
$ 21.98万
依托单位：
HUGO W. MOSER RES INST KENNEDY KRIEGER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2025-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10677602
关键词：
Anatomy Animal Model Biomedical Engineering Brain imaging Clinical Services Communities Computer software Computers Consultations Data Data Analyses Data Set Data Storage and Retrieval Dedications Development Education Environment Faculty Functional Magnetic Resonance Imaging Funding Goals Grant Human Image Industry Infrastructure Intellectual and Developmental Disabilities Research Centers Intellectual functioning disability Magnetic Resonance Magnetic Resonance Imaging Methodology Methods Mission Neurodevelopmental Disorder Neurology Participant Phenotype Physiologic pulse Physiological Prevention Procedures Process Progress Reports Quality Control Radiology Specialty Research Research Design Research Personnel Resources Scanning Scheme Scientist Sequence Analysis Services Stimulus Students Techniques Technology Training Transcranial magnetic stimulation United States National Institutes of Health Universities Update clinically significant computerized data processing design experience image processing imaging science innovation interest meetings mid-career faculty neuroimaging novel novel imaging technology novel strategies operation senior faculty symposium synergism tool training opportunity transcranial direct current stimulation

项目摘要

PROJECT SUMMARY/ABSTRACT – NEUROIMAGING CORE The overall mission of the Neuroimaging Core is the use of imaging science to better understand intellectual and developmental disabilities (IDD), their causes, treatments, and prevention. This mission is accomplished in two ways: (1) Innovation (Aim 1)–development of new techniques, paradigms, methodologies, hardware and software to conduct research not previously possible; and (2) Guidance (Aims 2-5)–proper use of new and existing techniques studies designed to expand our understanding of IDD. Core faculty and staff help to conceptualize, plan and implement stimulus paradigms, MRI pulse sequences, and data analysis schemes so that our advisees use state-of-the-art and novel imaging technology to best effect, with innovation capabilities and support from both NIH and Industry. These services include quality control procedures for assuring the best data for these studies. The Core faculty also guide users to seek synergies across different types of imaging data (anatomic, functional, spectroscopic, physiologic). We also provide expertise on MRI- compatible implementation of transcranial magnetic stimulation and transcranial direct current stimulation techniques that can be used complementarily to functional MRI. Importantly, the Neuroimaging Core exists as a dedicated research center, and investigators do not compete with clinical services for scan utilization. To achieve these overall goals, the overall Core aims are to: (1) to support and promote innovation through the use of imaging science; (2) maintain a state-of-the-art scientific, technical and intellectual environment; (3) guide the optimal application of advanced neuroimage acquisition and processing techniques; (4) coordinate Core activities throughout the IDDRC; and (5) contribute to the training functions of the Center.

项目摘要/摘要 - 神经影像学核心神经影像核心的总体使命是使用成像科学更好地理解智力和发育障碍（IDD），其原因，治疗和预防。这个任务是通过两种方式完成：（1）创新（目标1） - 新技术，范式，方法，硬件和软件以前无法进行研究；（2）指导（目标2-5） - 培训的使用旨在扩大我们对IDD的理解的新技术和现有技术研究。核心教职员工帮助概念化，计划和实施刺激范例，MRI脉冲序列和数据分析计划使我们的顾问使用最先进的新型成像技术来最大程度地效果，并通过创新 NIH和行业的能力和支持。这些服务包括针对的质量控制程序确保这些研究的最佳数据。核心教师还指导用户寻求不同的协同作用成像数据的类型（解剖，功能，光谱，生理学）。我们还提供有关MRI-的专业知识兼容跨界磁刺激和thrancranial直流电流刺激的实施可以完全用于功能性MRI的技术。重要的是，神经影像学核心存在一个专门的研究中心，研究人员没有与临床服务竞争扫描利用。到实现这些总体目标，总体核心目标是：（1）通过使用成像科学；（2）保持最先进的科学，技术和智力环境；（3）指导高级神经图像获取和处理技术的最佳应用；（4）坐标整个IDDRC的核心活动；（5）有助于中心的训练功能。