NEUROIMAGING CORE

神经影像核心

• 批准号: 10677602
• 负责人: Peter CM Van Zijl
• 金额: $ 21.98万
• 依托单位: HUGO W. MOSER RES INST KENNEDY KRIEGER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10677602
• 关键词: Anatomy; Animal Model; Biomedical Engineering; Brain imaging; Clinical Services; Communities; Computer software; Computers; Consultations; Data; Data Analyses; Data Set; Data Storage and Retrieval; Dedications; Development; Education; Environment; Faculty; Functional Magnetic Resonance Imaging; Funding; Goals; Grant; Human; Image; Industry; Infrastructure; Intellectual and Developmental Disabilities Research Centers; Intellectual functioning disability; Magnetic Resonance; Magnetic Resonance Imaging; Methodology; Methods; Mission; Neurodevelopmental Disorder; Neurology; Participant; Phenotype; Physiologic pulse; Physiological; Prevention; Procedures; Process; Progress Reports; Quality Control; Radiology Specialty; Research; Research Design; Research Personnel; Resources; Scanning; Scheme; Scientist; Sequence Analysis; Services; Stimulus; Students; Techniques; Technology; Training; Transcranial magnetic stimulation; United States National Institutes of Health; Universities; Update; clinically significant; computerized data processing; design; experience; image processing; imaging science; innovation; interest; meetings; mid-career faculty; neuroimaging; novel; novel imaging technology; novel strategies; operation; senior faculty; symposium; synergism; tool; training opportunity; transcranial direct current stimulation

PROJECT SUMMARY/ABSTRACT – NEUROIMAGING CORE The overall mission of the Neuroimaging Core is the use of imaging science to better understand intellectual and developmental disabilities (IDD), their causes, treatments, and prevention. This mission is accomplished in two ways: (1) Innovation (Aim 1)–development of new techniques, paradigms, methodologies, hardware and software to conduct research not previously possible; and (2) Guidance (Aims 2-5)–proper use of new and existing techniques studies designed to expand our understanding of IDD. Core faculty and staff help to conceptualize, plan and implement stimulus paradigms, MRI pulse sequences, and data analysis schemes so that our advisees use state-of-the-art and novel imaging technology to best effect, with innovation capabilities and support from both NIH and Industry. These services include quality control procedures for assuring the best data for these studies. The Core faculty also guide users to seek synergies across different types of imaging data (anatomic, functional, spectroscopic, physiologic). We also provide expertise on MRI- compatible implementation of transcranial magnetic stimulation and transcranial direct current stimulation techniques that can be used complementarily to functional MRI. Importantly, the Neuroimaging Core exists as a dedicated research center, and investigators do not compete with clinical services for scan utilization. To achieve these overall goals, the overall Core aims are to: (1) to support and promote innovation through the use of imaging science; (2) maintain a state-of-the-art scientific, technical and intellectual environment; (3) guide the optimal application of advanced neuroimage acquisition and processing techniques; (4) coordinate Core activities throughout the IDDRC; and (5) contribute to the training functions of the Center.

项目摘要/摘要--神经成像核心 神经成像核心的总体任务是利用成像科学更好地理解 智力和发育障碍(IDD)、其原因、治疗和预防。这项任务是 以两种方式实现：(1)创新(目标1)--开发新技术、新模式、新方法、 进行以前不可能进行的研究的硬件和软件；以及(2)指导(目标2-5)--正确使用 旨在扩大我们对IDD的理解的新的和现有的技术研究。核心教职员工 帮助概念化、计划和实施刺激范例、核磁共振脉冲序列和数据分析 方案，使我们的顾问使用最先进的和新颖的成像技术，以创新的方式实现最佳效果 来自NIH和行业的能力和支持。这些服务包括以下质量控制程序 确保为这些研究提供最佳数据。核心教师还指导用户在不同的领域寻求协同 成像数据的类型(解剖、功能、光谱、生理)。我们还提供核磁共振方面的专业知识- 经颅磁刺激与经颅直流电刺激的兼容实施 可作为功能磁共振的补充使用的技术。重要的是，神经成像核心作为 一个专门的研究中心，研究人员不会与临床服务竞争扫描利用率。至 实现这些总体目标，总体核心目标是：(1)通过 使用成像科学；(2)保持最先进的科学、技术和智力环境；(3) 指导优化应用先进的神经图像采集和处理技术；(4)协调 在整个国际发展和发展中心开展的核心活动；(5)促进中心的培训职能。