Midwest Roybal Center for Health Promotion and Translation

摘要总体 我们提议的UIC中西部Roybal健康促进和翻译中心旨在加快 将行为研究理论转化为实际成果，以改善功能和生活质量 年长的成年人。我们的工作认识到，针对个人的干预发生在家庭中， 社区，以及受外部因素影响的社区，这些外部因素影响着启蒙和 维持行为的改变。我们的工作是在RE-AIM框架的指导下确定健康促进 最有可能产生广泛公共卫生影响的干预措施。我们的中心将支持 设计和测试以原则为导向的、强有力的健康促进干预措施，这些干预措施具有很强的 在NIH阶段变化模型中取得进展。我们建议的续订中心目前的重点仍是 为老年种族/少数民族成年人设计干预措施，扩大我们健康行为的重点 干预措施包括认知健康。此续订申请针对四个重点主题领域：物理 促进活动；增强机动性，广义上包括改善认知功能步态、平衡、 和步行；利用技术来提高干预的可扩展性和保真度；并将 维持行为改变的行动机制。 我们的管理团队、高级领导和受资助试点项目的首席调查员将组成 中心研究学院。管理团队和高级领导有开展研究的经验 在阶段模式的所有阶段，并将努力使有前途的飞行员尽快过渡到各个阶段 有可能。试验计划督导计划将负责完成其计划中建议的所有活动。 对管理核心的监督。Pilot Core每年将为最多两名飞行员提供赠款资金， 从UIC和伊利诺伊大学其他校区的所有部门征集。续订中心 执行委员会由UIC的高级领导人和多个部门的主席组成，所有这些部门 对于完成中心的使命至关重要。中心的整体业绩将由一名 杰出的咨询委员会，包括来自不同学术机构、提供者、资助者、 消费者和媒体利益相关者群体。最后，这一续签申请首次纳入了 多模式ADRD成像和连接核心，将使调查人员能够执行大脑成像， 解释和储存，并提供统一的认知和体力活动测量。

Abstract Overall Our proposed UIC Midwest Roybal Center for Health Promotion and Translation seeks to accelerate the translation of behavioral research theories into practical outcomes to improve the functioning and quality of life of older adults. Our work recognizes that interventions that target individuals take place in families, neighborhoods, and communities that are impacted by external factors that influence initiation and maintenance of behavior change. Our work is guided by the RE-AIM Framework to identify health promotion interventions that have the greatest potential for broad based public health impact. Our Center will support the design and testing of principle-driven, potent health promotion interventions that have strong promise of progressing through the NIH Stage Change Model. Our proposed renewal Center retains its current focus on designing interventions for older racial/ethnic minority adults and expands the focus of our health behavior interventions to include cognitive health. This renewal application targets four thematic areas of focus: physical activity promotion; enhancing mobility, defined broadly to include improved cognitive function gait, balance, and walking; harnessing technology to improve intervention scalability and fidelity; and incorporating mechanisms of action that will sustain behavior change. Our Management team, Senior Leaders and Principal Investigators of funded pilot projects will constitute the Center Research Faculty. The Management team and Senior Leaders have experience conducting research across all stages of the Stage Model and will work to transition promising pilots across the Stages as quickly as possible. The Pilot PIs will be responsible for completing all activities proposed in their projects, under the oversight of the Management Core. The Pilot Core will provide grant funding for up to two pilots per year, solicited from all departments across UIC and other University of Illinois campuses. The renewal Center Executive Committee is comprised of Senior Leaders and Chairs of multiple departments at UIC, all of which are critical to fulfilling the mission of the Center. The overall performance of the Center will be guided by a distinguished Advisory Committee that includes representatives from diverse academic, provider, funder, consumer, and media stakeholder groups. Finally, this renewal application incorporates for the first time a Multi-modal ADRD Imaging and Connectomics Core that will enable investigators to perform brain imaging, interpretation, and storage and provide access to uniform cognitive and physical activity measures.