Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal ResearchNetwork

新墨西哥大学在新生儿研究方面有杰出的贡献记录 网络。我们的团队为包括氢化可的松在内的试验提供了主要研究人员的领导 BPD、Darbepoetin对早产儿的神经保护作用以及对早产儿神经保护的观察和干预研究 足月儿心血管功能不全。杰西·麦克斯韦尔博士开发了一种新的实验室检测方法 Darbepoetin为Darbe研究。我们一直支持我们的初级调查人员，包括新生儿研究员， 向该网络提出研究建议。随着马克斯韦尔博士作为这一申请的合作研究员的加入，我们 将继续发展我们的领导力。她是Idea State儿科临床研究所的初级研究员 UNM的试验网络(ISPCTN)，ACT NOWS研究的PI站点，并有一项经批准的ISPCTN试点研究。Dr。 Fuller在今年早些时候担任PI的角色，在我们前进的过程中提供领导；Watterberg博士将继续 作为替代PI，提供连续性。无论是在临床上还是在结果上，随访都是UNM的标志性优势 研究。这是由于洛博士、富勒博士和沃特伯格博士之间的密切合作。洛威博士 是母婴互动、行为结果和执行功能方面的知名研究人员 评估，以及一名NRN贝利金本位考官。我们的团队已经发表了创建一种 语言中立的发展评估和理解语言对发展的影响 测试。Lowe博士对早期工作记忆的研究，将其作为早期发展和发展的语言中性测量 作为语言和处理技能的重要预测者，6-7岁对 新生儿结局文献。沃特伯格博士获得了NHLBI的资金来研究肾上腺功能和 支持神经学龄儿童随访队列中6岁时的心血管结果。然后是洛博士 带头对这一队列中的行为结果以及这些结果之间的关系进行进一步的调查 皮质醇唤醒反应的结果。我们期望继续为成果作出重大贡献。 在下一个赠款周期内进行研究。新墨西哥州是一个少数族裔占多数的州，有48%的西班牙裔和9%的拉美裔 美洲原住民，拉美裔人口比例最高的州，仅次于阿拉斯加 对美洲原住民来说。我们的人口在北非地区是独一无二的，因为它的西班牙裔和原住民入学率很高 美国人，我们的通用数据库新生儿中有52%是西班牙裔，23%是美洲原住民 2006年，在同意的研究中，29-68%的西班牙裔和27-50%的美洲原住民婴儿。我们的记录是 贡献，我们在成果研究方面的专门知识，以及我们独特的人口，使UNM成为 NRN的特殊候选人。

The University of New Mexico has an outstanding track record of contributions to the Neonatal Research Network. Our team has provided leadership as Principal Investigators for trials including Hydrocortisone for BPD, Darbepoetin for Neuroprotection in Preterm Infants, and both an observational and interventional study of cardiovascular insufficiency in term infants. Dr. Jessie Maxwell developed a novel laboratory assay for darbepoetin for the DARBE study. We have supported our junior investigators, including neonatology fellows, in proposing studies to the network. With the addition of Dr. Maxwell as a co-investigator in this application, we will continue to develop our leadership. She is the junior investigator for the IDeA States Pediatric Clinical Trials Network (ISPCTN) at UNM, site PI for ACT NOWS studies and has an approved ISPCTN pilot study. Dr. Fuller took on the role of PI earlier this year, providing leadership as we go forward; Dr. Watterberg will remain as Alternate PI, providing continuity. Follow-up is a signature strength for UNM, both clinically and in outcomes research. This is made possible by the close collaboration among Drs. Lowe, Fuller, and Watterberg. Dr. Lowe is a well-established researcher in maternal-infant interactions, behavioral outcomes, and executive function evaluation, and an NRN Bayley Gold Standard examiner. Our team has published efforts to create a language-neutral developmental assessment and to understand the impact of language on developmental testing. Dr. Lowe’s studies of early working memory as a language-neutral measure of early development and as a significant predictor of verbal and processing skills at 6-7 years have been important contributions to the neonatal outcome literature. Dr. Watterberg obtained NHLBI funding to study adrenal function and cardiovascular outcomes at age 6 years in the SUPPORT NEURO school-age follow-up cohort. Dr. Lowe then spearheaded additional investigations of behavioral outcomes in this cohort and the relationship of these outcomes to cortisol awakening response. We expect to continue our significant contributions to outcomes research during the next grant cycle. New Mexico is a ‘minority majority’ state, with 48% Hispanic and 9% Native American individuals, the highest percentage of Hispanic individuals of any state and second to Alaska for Native Americans. Our population is unique in the NRN for its high enrollment of Hispanic and Native Americans, with 52% of our Generic Database newborns being Hispanic and 23% Native American since 2006, and 29 – 68% Hispanic and 27 – 50% Native American infants in consented studies. Our record of contributions, our specific expertise in outcomes research, and our unique population make UNM an exceptional candidate for the NRN.