Roybal Center for Behavioral Interventions in Aging

摘要 罗伊巴尔老龄行为干预中心的总体目的是加强 世界各地的临床医生都有能力推荐最安全、最有效的治疗方法 他们的病人通过行为经济干预。该中心的具体目标是： (1)开展行为干预开发和实施，鼓励适当 通过使用心理学和心理学的行为洞察力做出医疗决策 经济学；(2)为选择影响潜力最大的干预措施提供信息 通过使用模拟模型，以及(3)将这些发现转化为 影响老龄化政策的政策制定者。我们的中心将在NIH阶段模式下运行 用于创建从基础研究(阶段)开始的研究流水线的行为干预 0)通过全面传播干预措施(第五阶段)。工作将通过 管理和行政核心和研究是通过试点核心进行的。两名飞行员 这两项研究都是在第一年提出的，都与美国的阿片类药物危机有关。第一个是建立在 我们之前在通知医生他们的病人致命的过量用药方面的工作比较了两个 在与第四阶段研究一致的随机试验中，信件的框架不同。第二个是 一项可行性研究(第一阶段)，以评估哪些轻推可能会改善医生对 丁丙诺啡治疗阿片类药物使用障碍。推进这两个阶段的途径 对项目进行了讨论，并对未来几年的新试点进行了征集。与之前的延续 Roybal奖反映在该中心使用模拟来通知飞行员的选择，这将 对人口健康有最大的潜在影响。该中心将支持不断增长的 进行行为干预的研究人员社区，以鼓励适当使用 医疗治疗：阿片类药物处方、多药联用、抗生素处方、临床惰性 成瘾的药物辅助治疗，以及医疗决定的其他护理领域 与指导方针不符，并对人口健康产生负面影响。

Abstract The overall purpose of the Roybal Center for Behavioral Interventions in Aging is to strengthen the ability of clinicians everywhere to recommend the safest and most effective treatments for their patients through behavioral economic interventions. The specific aims of the Center are to: (1) Conduct behavioral intervention development and implementation to encourage appropriate medical treatment decisions through the use of behavioral insights from psychology and economics; (2) Inform the selection of these interventions with the greatest potential to impact population health through the use of simulation models, and (3) Translate these findings for policy makers who influence aging policy. Our Center will operate under the NIH Stage Model for behavioral interventions creating a pipeline of studies that span from basic research (Stage 0) through full-scale dissemination of interventions (Stage V). Work will be managed through a Management and Administrative Core and research is conducted through a Pilot Core. Two pilot studies are proposed in Year 1 both relating to the opioids crisis in the US. The first builds on our previous work in informing physicians of their patient’s fatal overdose comparing two differently framed letters in a randomized trial consistent with Stage IV research. The second is a feasibility study (Stage I) to evaluate what nudges are likely to improve physician uptake of buprenorphine for opioid use disorder. Pathways toward advancing the stages of these two projects are discussed as are solicitations for new pilots in out-years. Continuity with the prior Roybal award is reflected in the Center’s use of simulation to inform selection of pilots that will have the greatest potential for population health impact. The Center will support a growing community of researchers conducting behavioral interventions to encourage appropriate use of medical treatments: Opioid prescribing, polypharmacy, antibiotic prescribing, clinical inertia in medication assisted therapy for addiction, and other areas of care where medical decisions are discordant with guidelines and are having a negative impact on population health.