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Roybal Center for Behavioral Interventions in Aging

皇家衰老行为干预中心

基本信息

批准号：
9810956
负责人：
JASON N. DOCTOR
金额：
$ 64.15万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-30 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9810956
关键词：
Adverse event Affect Age-Years Aging American Antibiotic Resistance Antibiotics Area Attention Award Basic Science Behavior Therapy Behavioral Behavioral Model Behavioral Sciences Buprenorphine Cardiovascular Diseases Caring Cessation of life Clinical Code Communities Conscious Data Drug Interactions Economics Epidemic Evaluation Face Failure Feasibility Studies Funding Future Generations Guidelines Health Health Benefit Health Policy Healthcare Intervention Letters Libraries Longevity Manuals Medical Medication Management Opioid Overdose Pathway interactions Patients Persons Pharmaceutical Preparations Physicians Pilot Projects Policies Policy Maker Polypharmacy Population Psychology Research Research Personnel Research Support Side Social Psychology System Translating Translations Unconscious State United States National Institutes of Health Work addiction adverse drug reaction adverse outcome age group base behavioral economics clinical decision-making cost dissemination research effective therapy effectiveness research efficacy testing evidence base experience falls financial incentive healthy aging implementation research improved insight models and simulation mortality opioid epidemic opioid use disorder population health prescription opioid randomized trial research data dissemination response simulation software development therapy development treatment choice uptake

项目摘要

Abstract The overall purpose of the Roybal Center for Behavioral Interventions in Aging is to strengthen the ability of clinicians everywhere to recommend the safest and most effective treatments for their patients through behavioral economic interventions. The specific aims of the Center are to: (1) Conduct behavioral intervention development and implementation to encourage appropriate medical treatment decisions through the use of behavioral insights from psychology and economics; (2) Inform the selection of these interventions with the greatest potential to impact population health through the use of simulation models, and (3) Translate these findings for policy makers who influence aging policy. Our Center will operate under the NIH Stage Model for behavioral interventions creating a pipeline of studies that span from basic research (Stage 0) through full-scale dissemination of interventions (Stage V). Work will be managed through a Management and Administrative Core and research is conducted through a Pilot Core. Two pilot studies are proposed in Year 1 both relating to the opioids crisis in the US. The first builds on our previous work in informing physicians of their patient’s fatal overdose comparing two differently framed letters in a randomized trial consistent with Stage IV research. The second is a feasibility study (Stage I) to evaluate what nudges are likely to improve physician uptake of buprenorphine for opioid use disorder. Pathways toward advancing the stages of these two projects are discussed as are solicitations for new pilots in out-years. Continuity with the prior Roybal award is reflected in the Center’s use of simulation to inform selection of pilots that will have the greatest potential for population health impact. The Center will support a growing community of researchers conducting behavioral interventions to encourage appropriate use of medical treatments: Opioid prescribing, polypharmacy, antibiotic prescribing, clinical inertia in medication assisted therapy for addiction, and other areas of care where medical decisions are discordant with guidelines and are having a negative impact on population health.

抽象的皇家老龄化行为干预中心的总体目标是加强世界各地的临床医生有能力推荐最安全、最有效的治疗方法他们的患者通过行为经济干预。该中心的具体目标是： (1) 开展行为干预的制定和实施，以鼓励适当的行为干预通过使用心理学和行为学的见解来做出医疗决策经济学; (2) 告知如何选择最有可能产生影响的干预措施通过使用模拟模型来实现人口健康，以及 (3) 将这些发现转化为影响老龄化政策的政策制定者。我们的中心将在 NIH 阶段模式下运营行为干预创建了一系列研究，涵盖基础研究（阶段 0) 通过全面传播干预措施（第五阶段）。工作将通过一个管理和行政核心以及研究是通过试点核心进行的。两名飞行员第一年提出的研究均与美国的阿片类药物危机有关。第一个建立在我们之前的工作是向医生告知患者服药过量致死的情况，比较了两种药物的情况与第四阶段研究一致的随机试验中不同框架的字母。第二个是可行性研究（第一阶段），以评估哪些推动措施可能会提高医生的接受度丁丙诺啡用于治疗阿片类药物使用障碍。推进这两个阶段的途径讨论项目以及未来几年新试点的征集。与前文的连续性皇家奖体现在该中心使用模拟来选择飞行员，这些飞行员将对人口健康影响最大的潜力。该中心将支持不断增长的研究人员社区进行行为干预，以鼓励适当使用医疗治疗：阿片类药物处方、复方用药、抗生素处方、临床惯性成瘾药物辅助治疗，以及需要做出医疗决定的其他护理领域不符合指导方针，并对人口健康产生负面影响。