Optimizing a scalable intervention to maximize guideline-recommended diabetes testing after GDM

优化可扩展的干预措施,以最大限度地提高 GDM 后指南推荐的糖尿病检测

基本信息

  • 批准号:
    10682465
  • 负责人:
  • 金额:
    $ 70.86万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-09-12 至 2026-07-31
  • 项目状态:
    未结题

项目摘要

ABSTRACT Gestational diabetes mellitus (GDM) is a common complication that is routinely detected as part of standard prenatal care. After delivery, women with GDM are 7 times more likely to develop type 2 diabetes than those without GDM. National clinical guidelines thus urge completion of a 75-gram, 2-hour oral glucose tolerance test (OGTT), given its superior sensitivity to detect diabetes, by 12 weeks postpartum. Clinical guidelines also advise participation in an evidence-based lifestyle program for diabetes prevention. Yet uptake of this recommended care remains low, and evidence from randomized trials on interventions to increase uptake remains scarce. Here, we propose to test a novel, multi-component outreach intervention that explicitly targets as-yet neglected, patient-level motivational and logistical barriers to engaging in preventive care during the demanding postpartum period. We will leverage the multiphase optimization strategy (MOST) to identify, in a randomized factorial trial, which of four theory-driven components increase actual completion of postpartum screening and enrollment in lifestyle programs for diabetes prevention: 1) a streamlined values affirmation, 2) personalized information about diabetes risk, 3) an interactive motivational interviewing-based module, and 4) an interactive action planning module. Each component is designed to be self-directed and delivered securely online via existing infrastructure in a health system setting, increasing its future potential for large-scale reach. In a racially and ethnically diverse sample of women with GDM within the Kaiser Permanente Northern California (KPNC) health system, our specific aims are as follows. Aim 1: Identify which of four components of the outreach intervention increase completion of a) a 75-gram, 2-hour OGTT within 4-12 weeks postpartum, aligned with national clinical guidelines (primary outcome), and b) any postpartum diabetes screening test (OGTT, fasting plasma glucose, or hemoglobin A1c) by 52 weeks postpartum (secondary outcome). Aim 2: Identify which of four components of the outreach intervention increase enrollment in a health system- or community-based lifestyle program for diabetes prevention by 52 weeks postpartum (secondary outcome). Aim 3: Determine whether each intervention component impacts its target mediator, as predicted by its respective theory. We will efficiently and objectively assess screening outcomes via electronic health records. Results will yield an optimized intervention ready to be tested in a future pragmatic trial to accelerate uptake of guideline- recommended postpartum care for women with GDM, with the long-term goal of preventing diabetes in a diverse and high-risk clinical population.
摘要

项目成果

期刊论文数量(0)
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Susan Denise Brown其他文献

Susan Denise Brown的其他文献

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{{ truncateString('Susan Denise Brown', 18)}}的其他基金

Mentoring Diverse Early Career Researchers in Behavioral Diabetes Prevention Research
指导不同的早期职业研究人员进行行为糖尿病预防研究
  • 批准号:
    10794017
  • 财政年份:
    2023
  • 资助金额:
    $ 70.86万
  • 项目类别:
Optimizing a scalable intervention to maximize guideline-recommended diabetes testing after GDM
优化可扩展的干预措施,以最大限度地提高 GDM 后指南推荐的糖尿病检测
  • 批准号:
    10299312
  • 财政年份:
    2021
  • 资助金额:
    $ 70.86万
  • 项目类别:
Optimizing a scalable intervention to maximize guideline-recommended diabetes testing after GDM
优化可扩展的干预措施,以最大限度地提高 GDM 后指南推荐的糖尿病检测
  • 批准号:
    10488192
  • 财政年份:
    2021
  • 资助金额:
    $ 70.86万
  • 项目类别:
Motivational Determinants of Postpartum Lifestyle Behaviors, Weight Retention, and Metabolic Syndrome
产后生活方式行为、体重保持和代谢综合征的动机决定因素
  • 批准号:
    10462352
  • 财政年份:
    2019
  • 资助金额:
    $ 70.86万
  • 项目类别:
Motivational Determinants of Postpartum Lifestyle Behaviors, Weight Retention, and Metabolic Syndrome
产后生活方式行为、体重保持和代谢综合征的动机决定因素
  • 批准号:
    10548743
  • 财政年份:
    2019
  • 资助金额:
    $ 70.86万
  • 项目类别:
Motivational Determinants of Postpartum Lifestyle Behaviors, Weight Retention, and Metabolic Syndrome
产后生活方式行为、体重保持和代谢综合征的动机决定因素
  • 批准号:
    10319615
  • 财政年份:
    2019
  • 资助金额:
    $ 70.86万
  • 项目类别:
Motivational Determinants of Postpartum Lifestyle Behaviors, Weight Retention, and Metabolic Syndrome
产后生活方式行为、体重保持和代谢综合征的动机决定因素
  • 批准号:
    10064396
  • 财政年份:
    2019
  • 资助金额:
    $ 70.86万
  • 项目类别:
Understanding Patient Engagement in Lifestyle Programs for Diabetes Prevention among Women with a Recent History of GDM
了解近期有 GDM 病史的女性患者参与糖尿病预防生活方式计划的情况
  • 批准号:
    9298185
  • 财政年份:
    2017
  • 资助金额:
    $ 70.86万
  • 项目类别:
Engaging At-Risk Minority Women in Health System Diabetes Prevention Programs
让高危少数族裔妇女参与卫生系统糖尿病预防计划
  • 批准号:
    9057526
  • 财政年份:
    2014
  • 资助金额:
    $ 70.86万
  • 项目类别:
Engaging At-Risk Minority Women in Health System Diabetes Prevention Programs
让高危少数族裔妇女参与卫生系统糖尿病预防计划
  • 批准号:
    8767426
  • 财政年份:
    2014
  • 资助金额:
    $ 70.86万
  • 项目类别:

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