NICHD 临床中心/新生儿研究网络-猫眼课题宝

NICHD 临床中心/新生儿研究网络

批准号：

10681621

负责人：

Sara Bonamo DeMauro

金额：

$39.82万

依托单位：

UNIVERSITY OF PENNSYLVANIA

依托单位国家：

美国

项目类别：

财政年份：

2011

资助国家：

美国

项目状态：

未结题

起止时间：

2011-04-01 至 2030-03-31

来源：

https://reporter.nih.gov/project-details/10681621

关键词：

Admission activity Age Award Caring Clinic Clinical Clinical Research Clinical Trials Collaborations Conduct Clinical Trials Country Education Enrollment Ensure Epidemiologic Methods Faculty Follow-Up Studies Funding Future Goals Hybrids Infant Informed Consent Inpatients Intervention Lactation Leadership Manuscripts Milrinone Mission Multicenter Neonatal Research Network National Institute of Child Health and Human Development Neonatal Neonatal Intensive Care Units Neonatology Observational Study Outcome Outcome Study Outpatients Pediatric Hospitals Pennsylvania Perinatal Perinatology Philadelphia Principal Investigator Productivity Protocols documentation Publications Publishing Randomized Controlled Clinical Trials Records Research Research Methodology Research Personnel Resources Sample Size Schedule School-Age Population Scientific Advances and Accomplishments Secure Services Site Solid Structure Techniques Transfusion U-Series Cooperative Agreements Universities Visit Writing clinical care clinical center clinical trial enrollment clinical trial protocol cohort evidence base extreme prematurity fetal diagnosis follow-up health disparity high risk infant improved outcome innovation medical schools meetings member microbiome novel participant enrollment patient population pediatric department premature preterm newborn randomized trial recruit success symposium

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PROJECT SUMMARY The Eunice Kennedy Shriver NICHD cooperative multicenter Neonatal Research Network (NRN) is committed to providing a strong scientific evidence base for the care of sick and preterm newborns to promote healthy outcomes. Since 2011, the University of Pennsylvania Perelman School of Medicine (Penn) and Children’s Hospital of Philadelphia (CHOP) Clinical Center has been making significant contributions to all aspects of NRN research. Our Clinical Center includes three large level three neonatal intensive care units in academic perinatal centers, one large level four unit in a children’s hospital, and three follow-up clinics, all of which are unified under the leadership of the Penn/CHOP Division of Neonatology. We are a leading NRN Clinical Center for recruitment, retention, and study follow-up. We rank #3 among the 15 current Clinical Centers for number of infants recruited into the five currently ongoing randomized trials. Penn/CHOP 2-year follow-up rates are consistently higher than NRN average follow-up rates. Since we joined the NRN, we have conducted follow-up visits at 18-26 months corrected age in 98.5% (385 of 391) of Penn/CHOP study participants enrolled in 9 clinical trials. Our investigators and coordinators provide important leadership within the NRN, serving on multiple subcommittees and facilitating startup of new centers through the NRN Open Network mechanism. Our Principal Investigator leads two large school-age follow-up studies of NRN trials and Penn/CHOP investigators have published 27 NRN manuscripts as first or senior author since our last competitive renewal. We also provide unique contributions through our team’s expertise in innovative epidemiological techniques and health disparities. We are fully prepared to continue our robust participation in the NRN by contributing our team’s special strengths in clinical research methodology, collaborating as collegial and productive partners in ongoing studies, and introducing innovative new protocols to advance the scientific mission of the NICHD NRN in the next award cycle.

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