The Signal Transduction in the Immune System Conference

项目总结/摘要 此申请寻求FASEB夏季研究会议（SRC）的部分资金， 免疫系统中的转导”，将于2023年6月11日至15日在加利福尼亚州棕榈泉举行。的总目标 这次会议将提供一个关于信号机制的最新进展的全面调查 参与健康和疾病中免疫细胞的反应。2023年的会议将是第11届 这次FASEB会议的召开。原定于2021年6月举行，但已推迟 由于新型冠状病毒大流行，这个特殊的FASEB会议历史上吸引了 学术界和工业界的广泛兴趣，因为杰出的发言者名册，削减 边缘性质的工作提出，以及相关的许多介绍免疫疾病。 此外，由于大多数主流免疫学会议不提供信号的深入关注， 转导机制，这个专门的FASEB会议吸引了免疫信号领域的领导者 世界范围内的转导，以及新的研究人员和学生。2023年会议的主题包括 天然免疫细胞感应，白细胞粘附和迁移，淋巴细胞信号，信号和效应 功能，以及健康和疾病中的免疫信号。我们预计，这些主题将吸引广泛的 在基础和转化领域都有大量的研究人员。虽然会议有一个定期的骨干 与会者和发言者，我们已经确保新的想法和研究领域将在2021年解决， 邀请了12位新的演讲者（共35位）。我们还优先考虑妇女的代表性（45%的 代表性不足的少数群体（在受邀发言者中）。此外，所有会议将有 简短演讲的空间（将从摘要中选择）。2023年会议的新成员是两个闪电 培训班，学员共20次1分钟的演讲，以突出他们的海报展示 （摘自摘要）。短期会谈将优先考虑新的研究人员，博士后研究员， 学生来自PI不在场的团体。这将确保会议的主题和发言者的多样性。 会议会议的总体目标是：（1）对最近的 控制先天性和适应性免疫系统的信号通路的进展; 2）汇集 不同的科学家群体在所有职业阶段（包括博士后研究员和学生）的两个 在一个激励和支持的气氛中，包括正式介绍和非正式讨论; 3)为受训人员和早期职业科学家提供机会，向更广泛的 4）通过广泛的研究，推动免疫系统分子机制的研究， 传播信息和最近的突破。我们预计，这次会议将在 过去的会议在影响免疫系统信号研究方向方面的成功。

PROJECT SUMMARY/ABSTRACT This application seeks partial funding for a FASEB Summer Research Conference (SRC) on "Signal Transduction in the Immune System", to be held June 11-15, 2023 in Palm Springs, CA. The overall goal of this conference is to provide a comprehensive survey of recent advances regarding the signaling mechanisms involved in the response of immune cells in both health and disease. The meeting in 2023 will be the 11th occurrence of this FASEB conference. It was originally scheduled in June 2021 but has been postponed multiple times due to the COVID pandemic. This particular FASEB conference has historically attracted widespread interest from both academia and industry because of the outstanding speaker rosters, the cutting edge nature of the work presented, and the relevance of many presentations to immunologic diseases. Additionally, since most mainstream immunology meetings do not provide an in-depth focus on signal transduction mechanisms, this dedicated FASEB conference has attracted leaders in immune signal transduction worldwide, as well as new investigators and students. Topics for the 2023 conference include innate immune cell sensing, leukocyte adhesion and migration, lymphocyte signaling, signaling and effector function, and immune signaling in health and disease. We anticipate that these topics will appeal to a broad swath of researchers in both basic and translational areas. Although the conference has a backbone of regular attendees and speakers, we have ensured that new ideas and research areas will be addressed in 2021 by featuring 12 new invited speakers (out of 35). We have also prioritized representation of women (45% of speakers) and underrepresented minorities (among the invited speakers. In addition, all sessions will have space for short talks (which will be selected from abstracts). New to the 2023 conference are two Lightning Sessions with a total of twenty 1-minute talks from trainees to highlight their poster session presentations (selected from abstracts). Priority for short talks will be given to new investigators, post-doctoral fellows, and students from groups in which PIs are not presenting. This will ensure a diversity of topics and speakers at the meeting. The overall objectives of the meeting are: 1) To provide a critical and intensive overview of the recent advances in signaling pathways controlling the innate and adaptive immune systems; 2) To bring together a diverse group of scientists across all career stages (including postdoctoral fellows and students) of both genders, in a stimulating and supportive atmosphere involving formal presentations and informal discussions; 3) To provide opportunities for trainees and early-career scientists to present their research to a broader scientific community; and 4) To advance research on molecular mechanisms in the immune system by broadly disseminating information and recent breakthroughs. We anticipate that this conference will build upon the success of past conferences in influencing the direction of signaling research in the immune system.