WU-SN-TMC Admin Core

WU-SN-TMC 管理核心

• 批准号: 10685419
• 负责人: Li Ding
• 金额: $ 26.55万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10685419
• 关键词: Advisory Committees; Atlases; Biological; Biological Markers; Bone Marrow; Breast; Budgets; Cell Aging; Clinical; Collaborations; Colon; Communication; Companions; Data; Data Analyses; Data Coordinating Center; Deposition; Development; Elements; Ensure; Environment; Fostering; Foundations; Funding; Generations; Goals; Human; Image; Infrastructure; Institution; Leadership; Liver; Maps; Mission; Monitor; Oncology; Patients; Pilot Projects; Positioning Attribute; Preparation; Progress Reports; Proteomics; Quality Control; Recording of previous events; Records; Research; Research Personnel; Resolution; Resources; Role; Scholarship; Science; Services; Site Visit; Technology; The Cancer Genome Atlas; Tissue atlas; Tissues; Translating; United States National Institutes of Health; Universities; Washington; Work; data sharing; experience; innovation; meetings; member; multidisciplinary; operation; outreach; patient advocacy group; patient derived xenograft model; programs; repository; senescence; success; synergism; technology development; timeline; tissue mapping; tumor; web site

Administrative Core Project Summary/Abstract Administrative Core will provide executive oversight and administrative support for the construction of atlases of cellular senescence for bone marrow, breast, colon, and liver tissue types by the Washington University Cellular Senescence Tissue Mapping Center (WU-SN-TMC). We will also provide fiscal oversight and infrastructure for communications across the three Cores, namely Biospecimen Core (BC), Biological Analysis Core (BAC), and Data Analysis Core (DAC), and for scientific collaborations within the Cellular Senescence Network (SenNet) and other companion NIH initiatives. The Administrative Core will administer a Pilot Project program to draw on the best emerging scientific ideas and technologies to understand the biological mechanisms governing senescence and advance the mission of the WU-SN-TMC and the entire SenNet. The Administrative Core leadership team has a long history of participating in, and taking leadership roles within, NIH-sponsored, multi-institutional networks; we will build on these experiences to work closely with the Consortium Organization and Data Coordination Center (CODCC), technology development projects, and other Tissue Mapping Centers (TMCs) to ensure the overall success of WU-SN-TMC and NIH SenNet program.

行政核心项目摘要/摘要 行政核心将为地图集的建设提供行政监督和行政支持 华盛顿大学对骨髓、乳腺、结肠和肝脏组织类型的细胞衰老的研究 细胞衰老组织图谱中心（WU-SN-TMC）。我们还将提供财政监督和 跨三个核心的通信基础设施，即生物样本核心 (BC)、生物分析 核心 (BAC) 和数据分析核心 (DAC)，以及细胞衰老领域的科学合作 网络 (SenNet) 和其他 NIH 配套举措。行政核心将管理一个试点项目 计划利用最好的新兴科学思想和技术来了解生物 管理衰老的机制并推进 WU-SN-TMC 和整个 SenNet 的使命。这 行政核心领导团队在参与并发挥领导作用方面有着悠久的历史， NIH 赞助的多机构网络；我们将在这些经验的基础上与 联盟组织和数据协调中心（CODCC）、技术开发项目以及 其他组织作图中心 (TMC)，以确保 WU-SN-TMC 和 NIH SenNet 的整体成功 程序。